AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass
Journal Article
Shah, M., Kola, B., Bataveljic, A., Arnett, T. R., Viollet, B., Saxon, L., …Chenu, C. AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass. BONE, 47(2), 309-319. https://doi.org/10.1016/j.bone.2010.04.596
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The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice
Journal Article
Gohin, S., Carriero, A., Chenu, C., Pitsillides, A. A., Arnett, T. R., & Marenzana, M. (in press). The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice. Cell Biochemistry and Function, 34(2), 52-62. https://doi.org/10.1002/cbf.3164
Expression of Semaphorin-3A and its receptors in endochondral ossification: Potential role in skeletal development and innervation
Journal Article
Gomez, C., Burt-Pichat, B., Mallein-Gerin, F., Merle, B., Delmas, P. D., Skerry, T. M., …Chenu, C. Expression of Semaphorin-3A and its receptors in endochondral ossification: Potential role in skeletal development and innervation. Developmental Dynamics, 234(2), 303-403. https://doi.org/10.1002/dvdy.20512
Sympathetic nervous system does not mediate the load-induced cortical new bone formation
Journal Article
De Souza, R. L., Pitsillides, A. A., Lanyon, L. E., Skerry, T. M., & Chenu, C. Sympathetic nervous system does not mediate the load-induced cortical new bone formation. Journal of Bone and Mineral Research, 20(12), 2159-2168. https://doi.org/10.1359/JBMR.050812
Dramatic decrease of innervation density in bone after ovariectomy
Journal Article
Burt-Pichat, B., Lafage-Proust, M. H., Duboeuf, F., Laroche, N., Itzstein, C., Vico, L., …Chenu, C. Dramatic decrease of innervation density in bone after ovariectomy. Endocrinology, 146(1), 503-510. https://doi.org/10.1210/en.2004-0884
NMDA glutamate receptors are expressed by osteoclast precursors and involved in the regulation of osteoclastogenesis
Journal Article
Merle, B., Itzstein, C., Delmas, P. D., & Chenu, C. NMDA glutamate receptors are expressed by osteoclast precursors and involved in the regulation of osteoclastogenesis. Journal of Cellular Biochemistry, 90(2), 424-436. https://doi.org/10.1002/jcb.10625
Osteoclast spreading kinetics are correlated with an oscillatory activation of a calcium-dependent potassium current
Journal Article
Espinosa, L., Paret, L., Ojeda, C., Tourneur, Y., Delmas, P. D., & Chenu, C. Osteoclast spreading kinetics are correlated with an oscillatory activation of a calcium-dependent potassium current. Journal of Cell Science, 115(19), 3837-3848. https://doi.org/10.1242/jcs.00062
Sympathetic nervous system and bone adaptive response to its mechanical environment
Journal Article
Marenzana, M., & Chenu, C. Sympathetic nervous system and bone adaptive response to its mechanical environmentWhile bone adaptive response to its mechanical environment was considered to be controlled locally by cytokines and systemic hormones, some recent work suggests that it could also be neuronally regulated. Bone is indeed very densely innervated and ma... Read More about Sympathetic nervous system and bone adaptive response to its mechanical environment.
Absence of mechanical loading in utero influences bone mass and architecture but not innervation in Myod-Myf5-deficient mice
Journal Article
Gomez, C., David, V., Peet, N. M., Vico, L., Chenu, C., Malaval, L., & Skerry, T. M. Absence of mechanical loading in utero influences bone mass and architecture but not innervation in Myod-Myf5-deficient mice. Journal of Anatomy, 210(3), 259-271. https://doi.org/10.1111/j.1469-7580.2007.00698.x
Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice
Journal Article
Nunes, A. F., Liz, M. A., Franquinho, F., Teixeira, L., Sousa, V., Chenu, C., …Sousa, M. M. Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice. FEBS Journal, 277(1), 263-275. https://doi.org/10.1111/j.1742-4658.2009.07482.x
Mice lacking AMP-activated protein kinase alpha 1 catalytic subunit have increased bone remodeling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment.
Journal Article
Jeyabalan, J., Shah, M., Viollet, B., Roux, J. P., Chavassieux, P., Korbonits, M., & Chenu, C. Mice lacking AMP-activated protein kinase alpha 1 catalytic subunit have increased bone remodeling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment. Journal of Endocrinology, 214(3), 349-358. https://doi.org/10.1530/JOE-12-0184
AMP-activated protein kinase pathway and bone metabolism
Journal Article
Jeyabalan, J., Shah, M., Viollet, B., & Chenu, C. AMP-activated protein kinase pathway and bone metabolism. Journal of Endocrinology, 212(3), 277-290. https://doi.org/10.1530/joe-11-0306
Mammalian Sulf1 RNA alternative splicing and its significance to tumour growth regulation
Journal Article
Gill, R. B. S., Day, A., Barstow, A., Zaman, G., Chenu, C., & Dhoot, G. K. Mammalian Sulf1 RNA alternative splicing and its significance to tumour growth regulation. https://doi.org/10.1007/s13277-012-0423-2
The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing
Journal Article
Jeyabalan, J., Viollet, B., Smitham, P., Ellis, S. A., Zaman, G., Bardin, C., …Chenu, C. The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing. Osteoporosis International, 24(10), 2659. https://doi.org/10.1007/s00198-013-2371-0
Nervous system and bone mechanoregulation
Journal Article
Chenu, C. Nervous system and bone mechanoregulation. Osteoporosis International, 25, S475-+