Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage

West, E; Osborne, C; Nolan, W; Bate, C

doi:10.3390/biology4020367

All Outputs (2)

Glimepiride protects neurons against amyloid-beta-induced synapse damage (2016)
Journal Article
Osborne, C., West, E., Nolan, W., McHale-Owen, H., Williams, A., & Bate, C. (2016). Glimepiride protects neurons against amyloid-beta-induced synapse damage. Neuropharmacology, 101, 225-236. https://doi.org/10.1016/j.neuropharm.2015.09.030

Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage
Journal Article
West, E., Osborne, C., Nolan, W., & Bate, C. (in press). Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage. Biology, 4(2), 367-82. https://doi.org/10.3390/biology4020367

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) and the loss of synapses. Aggregation of the cellular prion protein (PrPC) by Aβ oligomers induced synapse damage in cultured neur... Read More about Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage.