All Outputs (12)

Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection (2021)
Journal Article
Al-Neama, R., Bown, K., Blake, D., & Birtles, R. (2021). Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection. Parasitology, 148(5), 623-629. https://doi.org/10.1017/S0031182021000044

Coccidiosis caused by Eimeria species is a well-recognized disease of livestock. Enteric Eimeria infections are common, but disease usually only manifests when infection intensity is abnormally high. Campylobacter species are important zoonotic enter... Read More about Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection.

Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria (2021)
Journal Article
Nzelu, I., Kwaga, J., Kabir, J., Lawal, I., Beazley, C., Evans, L., & Blake, D. (2021). Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria. PLoS Neglected Tropical Diseases, 15(6), https://doi.org/10.1371/journal.pntd.0009458

Toxoplasma gondii parasites present strong but geographically varied signatures of population structure. Populations sampled from Europe and North America have commonly been defined by over-representation of a small number of clonal types, in contras... Read More about Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria.

Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines (2021)
Journal Article
Bremner, A., Kim, S., Morris, K., Nolan, M., Borowska, D., Wu, Z., Tomley, F., Blake, D., Hawken, R., Kaiser, P., & Vervelde, L. (2021). Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines. Frontiers in Immunology, 12, https://doi.org/10.3389/fimmu.2021.653085

Eimeria maxima is a common cause of coccidiosis in chickens, a disease that has a huge economic impact on poultry production. Knowledge of immunity to E. maxima and the specific mechanisms that contribute to differing levels of resistance observed be... Read More about Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines.

Genetic diversity within the 18S rRNA and actin locus of Cryptosporidium scrofarum (Apicomplexa: Cryptosporidiidae) infecting domestic pigs (Sus scrofa domesticus) of India (2021)
Journal Article
Sharma, D., Singh, N., Singh, H., Rath, S., & Blake, D. (2021). Genetic diversity within the 18S rRNA and actin locus of Cryptosporidium scrofarum (Apicomplexa: Cryptosporidiidae) infecting domestic pigs (Sus scrofa domesticus) of India. Veterinarski Arhiv, 91(3), 269-276. https://doi.org/10.24099/vet.arhiv.0674

The genetic diversity was studied of Cryptosporidium scrofarum (syn Cryptosporidium pig genotype II) of domestic pigs (Sus scrofa domesticus) from Punjab, India. Nested PCR amplification targeting the 18S rRNA and actin gene loci from Cryptosporidium... Read More about Genetic diversity within the 18S rRNA and actin locus of Cryptosporidium scrofarum (Apicomplexa: Cryptosporidiidae) infecting domestic pigs (Sus scrofa domesticus) of India.

Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2 (2021)
Journal Article
Attree, E., Sanchez-Arsuaga, G., Jones, M., Xia, D., -Hernandez, M., Blake, D., & Tomley, F. (2021). Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, https://doi.org/10.1186/s43170-021-00056-5

Coccidiosis is a potentially severe enteritis caused by species of obligate intracellular parasites of the genus Eimeria. These parasites cause significant economic losses to the poultry industry, predominantly due to compromised efficiency of produc... Read More about Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2.

Enhancing the value of meat inspection records for broiler health and welfare surveillance: longitudinal detection of relational patterns (2021)
Journal Article
Buzdugan, S., Alarcon, P., Huntington, B., Rushton, J., Blake, D., & Guitian, J. (in press). Enhancing the value of meat inspection records for broiler health and welfare surveillance: longitudinal detection of relational patterns. BMC Veterinary Research, https://doi.org/10.1186/s12917-021-02970-2

Background. Abattoir data are under-used for surveillance. Nationwide surveillance could benefit from using data on meat inspection findings, but several limitations need to be overcome. At the producer level, interpretation of meat inspection findin... Read More about Enhancing the value of meat inspection records for broiler health and welfare surveillance: longitudinal detection of relational patterns.

Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria (2021)
Journal Article
Nzelu, I., Kwaga, J., Kabir, J., Lawal, I., Beazley, C., Evans, L., & Blake, D. (2021). Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria. PLoS Neglected Tropical Diseases, https://doi.org/10.1371/journal.pntd.0009458

Toxoplasma gondii parasites present strong but geographically varied signatures of population structure. Populations sampled from Europe and North America have commonly been defined by over-representation of a small number of clonal types, in contras... Read More about Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria.

Spotlight on avian pathology: Eimeria and the disease coccidiosis (2021)
Journal Article
Blake, D. P., Marugan-Hernandez, V., & Tomley, F. M. (in press). Spotlight on avian pathology: Eimeria and the disease coccidiosis. Avian Pathology, https://doi.org/10.1080/03079457.2021.1912288

More than 72 billion chickens were produced globally in 2019, emphasising their major contribution to the production of protein for human consumption. Production systems for chickens are increasingly moving towards drug-free and/or extensive programm... Read More about Spotlight on avian pathology: Eimeria and the disease coccidiosis.

The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family (2021)
Journal Article
Ramly, N. Z., Dix, S. R., Ruzheinikov, S. N., Sedelnikova, S. E., Baker, P. J., Chow, Y.-P., Tomley, F. M., Blake, D. P., Wan, K.-L., Nathan, S., & Rice, D. W. (2021). The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family. Communications Biology, 4(1), Article 376. https://doi.org/10.1038/s42003-021-01904-w

In infections by apicomplexan parasites including Plasmodium, Toxoplasma gondii, and Eimeria, interactions with the host are mediated by numerous proteins including families of membrane-anchored cysteine-rich surface antigens (SAGs) and SAG-related s... Read More about The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family.

Genetic and biological characterisation of three cryptic Eimeria operational taxonomic units that infect chickens (Gallus gallus domesticus) (2021)
Journal Article
Blake, D., Blake, D., Vrba, V., Xia, D., Xia, D., Tomley, F., Danladi Jatau, I., Spiro, S., Nolan, M. J., Underwood, G., & Tomley, F. (2021). Genetic and biological characterisation of three cryptic Eimeria operational taxonomic units that infect chickens (Gallus gallus domesticus). International Journal for Parasitology,

More than 68 billion chickens were produced globally in 2018, emphasising their major contribution to the production of protein for human consumption, and the importance of their pathogens. Protozoan Eimeria species are the most economically signific... Read More about Genetic and biological characterisation of three cryptic Eimeria operational taxonomic units that infect chickens (Gallus gallus domesticus).

Molecular identification of Sarcocystis wobeseri-like parasites in a new intermediate host species, the white-tailed sea eagle (Haliaeetus albicilla) (2021)
Journal Article
Shadbolt, T., Pocknell, A., Sainsbury, A., Egerton-Read, S., & Blake, D. P. (2021). Molecular identification of Sarcocystis wobeseri-like parasites in a new intermediate host species, the white-tailed sea eagle (Haliaeetus albicilla). Parasitology Research, https://doi.org/10.1007/s00436-021-07103-0

A reintroduced white-tailed sea eagle (Haliaeetus albicilla) in moderate body condition was found dead and submitted for post-mortem examination. There were no signs of disease on gross pathological examination. Histopathological examination however... Read More about Molecular identification of Sarcocystis wobeseri-like parasites in a new intermediate host species, the white-tailed sea eagle (Haliaeetus albicilla).

Impact of Eimeria tenella oocyst dose on parasite replication, lesion score and cytokine transcription in the caeca in three breeds of commercial layer chickens (2021)
Journal Article
Soutter, F., Werling, D., Kim, S., Pastor-Fernández, I., Marugan-Hernandez, V., Tomley, F., & Blake, D. (in press). Impact of Eimeria tenella oocyst dose on parasite replication, lesion score and cytokine transcription in the caeca in three breeds of commercial layer chickens. Frontiers in Veterinary Science,

Eimeria species parasites infect the gastrointestinal tract of chickens, causing disease and impacting on production. The poultry industry relies on anticoccidial drugs and live vaccines to control Eimeria and there is a need for novel, scalable alte... Read More about Impact of Eimeria tenella oocyst dose on parasite replication, lesion score and cytokine transcription in the caeca in three breeds of commercial layer chickens.