A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals
(2023)
Journal Article
Gerri, C., McCarthy, A., Scott, G., Regin, M., Stamatiadis, P., Brumm, S., Simon, C., Lee, J., Montesinos, C., Hassitt, C., Hockenhull, S., Hampshire, D., Elder, K., Snell, P., Christie, L., Fouladi-Nashta, A., Van de Velde, H., & Niakan, K. (2023). A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals. Development, 150(8), https://doi.org/10.1242/dev.201112
Our understanding of the molecular events driving cell specification in early mammalian development relies mainly on mouse studies, and it remains unclear whether these mechanisms are conserved across mammals, including humans. We have shown that the... Read More about A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals.