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All Outputs (208)

Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management (2025)
Journal Article
O'Neill, D., Mustikka, M. P., Brodbelt, D. C., Church, D. B., & Vaattovaara, V. (2025). Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management. Herpetological Conservation and Biology, 20(6), e0326526. https://doi.org/10.1371/journal.pone.0326526

Introduction Natural eyelid conformation is essential for normal function and health of the ocular surface. However, many modern dog types are deliberately bred for abnormal eyelid conformation associated with severe health and welfare issues. This s... Read More about Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management.

Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs (2025)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y.-M., Boswood, A., Wilshaw, J., Reep, C. A. T., Balling, S., Sahota, J., Church, D. B., & O’Neill, D. G. (2025). Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs. PLoS ONE, 20(6), e0325695. https://doi.org/10.1371/journal.pone.0325695

Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019 (2025)
Journal Article
Waite, O., O'Neill, D. G., Wright, E., Gostelow, R., Jepson, R. E., & Brodbelt, D. C. (2025). Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019. Herpetological Conservation and Biology, 39(4), e70161. https://doi.org/10.1111/jvim.70161

Background: Diabetes mellitus (DM) is a common endocrinopathy in cats. General population epidemiology and mortality
studies on DM are lacking.
Objectives: Describe the incidence, prevalence, risk factors, and mortality for DM in cats under primary... Read More about Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019.

Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK (2025)
Journal Article
O'Neill, D., Prisk, L. J., Brodbelt, D. C., Church, D. B., & Allerton, F. (2025). Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK. PLoS ONE, 20(6), e0324203. https://doi.org/10.1371/journal.pone.0324203

Background
Acute diarrhoea is a common canine veterinary presentation in the UK. This study
aimed to report the incidence, demographic risk factors and clinical management for
acute diarrhoea diagnosed under primary veterinary care in the UK in 20... Read More about Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK.

Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice (2025)
Journal Article
Taylor, C., Barry, G. J., O’Neill, D. G., Guillén, A., Price, P. P., Labadie, J., & Brodbelt, D. C. (2025). Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice. PLoS ONE, 20(6), e0316066. https://doi.org/10.1371/journal.pone.0316066

Visceral haemangiosarcoma is considered clinically aggressive in dogs, with perceived
poor prognosis often leading to euthanasia at presentation. This study aimed
to determine survival times and prognostic factors in dogs with haemangiosarcoma
und... Read More about Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice.

Dental disease in rabbits under UK primary veterinary care: Clinical management and associated welfare impacts (2025)
Journal Article
Jackson, M., O'Neill, D., Hedley, J., Brodbelt, D., & Burn, C. (2025). Dental disease in rabbits under UK primary veterinary care: Clinical management and associated welfare impacts. Veterinary Record, https://doi.org/10.1002/vetr.5326

Background: Dental disease is painful and highly prevalent in companion rabbits, but current veterinary management techniques and clinical welfare implications are little described.
Methods: Anonymised VetCompass clinical records were manually revi... Read More about Dental disease in rabbits under UK primary veterinary care: Clinical management and associated welfare impacts.

Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs (2025)
Journal Article
O'Neill, D., Becker, S. D., Frosini, S.-M., Stapleton, L. E., Hughes, D. M., & Brodbelt, D. C. (2025). Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs. PLoS ONE, 20(2), e0318734. https://doi.org/10.1371/journal.pone.0318734

Standard bodyweights are an essential component of calculations that summarise many
population-level measures in companion animals, including the defined daily doses for
veterinary species (DDDVet) reporting antimicrobial usage. Standard species bo... Read More about Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs.

Beagles kept as companion animals in the UK – demography, disorders and mortality (2025)
Journal Article
O'Neill, D., Schiksnis, M. R., Brodbelt, D. C., Church, D. B., Goldberg, S., & Engdahl, K. S. (2025). Beagles kept as companion animals in the UK – demography, disorders and mortality. Companion Animal Health and Genetics, 12(1), https://doi.org/10.1186/s40575-024-00140-9

Background Beagles are a popular companion animal dog breed and are generally stated to be a healthy breed.
This VetCompass study aimed to report the demography, common disorders and mortality of Beagles under primary
veterinary care in the UK. Ano... Read More about Beagles kept as companion animals in the UK – demography, disorders and mortality.

Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study (2024)
Journal Article
O'Neill, D., Williams, A., Brodbelt, D. C., Church, D. B., & Hedley, J. (2024). Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study. Herpetological Conservation and Biology, https://doi.org/10.1002/vetr.4396

Abstract Background Domestic rabbit breeds vary substantially from the wild rabbit body type. However, little is known about how the conformation of pet rabbits influences their health. Methods Data were extracted from VetCompass anonymised clinical... Read More about Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study.

Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study (2024)
Journal Article
O'Neill, D., Diaz-Ordaz, K., Pegram, C., Brodbelt, D. C., Chang, Y.-M., Hall, J. L., & Church, D. B. (2024). Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study. Herpetological Conservation and Biology, 19(7), e0305526. https://doi.org/10.1371/journal.pone.0305526

There is growing evidence supporting clinically important associations between age at neutering in bitches and subsequent urinary incontinence (UI), although much of this evidence to date is considered weak. Target trial emulation is an innovative ap... Read More about Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study.

Life tables of annual life expectancy and risk factors for mortality in cats in the UK (2024)
Journal Article
O'Neill, D., Kendy Tzu-yun, T., Dave C, B., & David B, C. (2024). Life tables of annual life expectancy and risk factors for mortality in cats in the UK. Herpetological Conservation and Biology, 26(5), 1098612X241234556. https://doi.org/10.1177/1098612x241234556

ObjectivesThe aims of the present study were to generate the first life tables for the UK companion cat population overall as well as broken down by sex and breed status, and to quantify associations between mortality and traits such as sex, neuter s... Read More about Life tables of annual life expectancy and risk factors for mortality in cats in the UK.

The epidemiology of tick infestation in dog breeds in the UK (2024)
Journal Article
O'Neill, D., Komutrattananon, R., Hartley, A., Brodbelt, D., & Church, D. (2024). The epidemiology of tick infestation in dog breeds in the UK. Herpetological Conservation and Biology, https://doi.org/10.1111/jsap.13727

Objectives: The purpose of this study is to report the prevalence and risk factors for tick infestation in
dogs in the UK based on anonymised electronic patient records.
Materials and Methods: Clinical records of dogs under veterinary care in 2016... Read More about The epidemiology of tick infestation in dog breeds in the UK.

Demography, commonly diagnosed disorders and mortality of guinea pigs under primary veterinary care in the UK in 2019—A VetCompass study (2024)
Journal Article
O'Neill, D., Taffinder, J. L., Brodbelt, D. C., & Baldrey, V. (2024). Demography, commonly diagnosed disorders and mortality of guinea pigs under primary veterinary care in the UK in 2019—A VetCompass study. PLoS ONE, 19(3), https://doi.org/10.1371/journal.pone.0299464

Introduction
Guinea pigs are popular as domestic pets but there is limited information on the health of the
wider pet population. This study aimed to report demography, commonly diagnosed disorders
and mortality of guinea pigs under UK primary vet... Read More about Demography, commonly diagnosed disorders and mortality of guinea pigs under primary veterinary care in the UK in 2019—A VetCompass study.

Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes? (2024)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y.-M., von Hekkel, A. F., Wu, C.-H., Church, D. B., & O’Neill, D. G. (2024). Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes?. Preventive Veterinary Medicine, 106165. https://doi.org/10.1016/j.prevetmed.2024.106165

Target trial emulation applies design principles from randomised controlled trials to the analysis of observational data for causal inference and is increasingly used within human epidemiology. Using anonymised veterinary clinical data from the VetCo... Read More about Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes?.

Dental disease in companion rabbits under UK primary veterinary care: frequency and risk factors (2024)
Journal Article
Jackson, M., Burn, C., Hedley, J., Brodbelt, D., & O'Neill, D. (2024). Dental disease in companion rabbits under UK primary veterinary care: frequency and risk factors. Veterinary Record, https://doi.org/10.1002/vetr.3993

Background-
Some prior evidence has suggested rabbits with lop ear and brachycephalic skull conformations have higher dental disease risk. This retrospective cohort study reports the frequency and conformational risk factors for primary-care veterin... Read More about Dental disease in companion rabbits under UK primary veterinary care: frequency and risk factors.

Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK (2024)
Journal Article
O'Neill, D., Brodbelt, D., Church, D., & Dale, F. (2024). Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK. Herpetological Conservation and Biology, 11(1), 2. https://doi.org/10.1186/s40575-023-00135-y

Background Shih Tzus are a popular dog breed in the UK although there is relatively little reported information
on their health. This study aimed to characterise the demography, common disorders and mortality of Shih Tzus
under primary veterinary c... Read More about Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK.

A study of the impact of the COVID-19 pandemic on equine veterinary care in the UK (2023)
Journal Article
Allen, S., O'Neill, D., Cardwell, J., Verheyen, K., & Brodbelt, D. (2023). A study of the impact of the COVID-19 pandemic on equine veterinary care in the UK. Vet Record Open, 10(2), https://doi.org/10.1002/vro2.74

BackgroundDuring the COVID-19 pandemic, equine health care in the UK may have been adversely affected due to mandated changes in the delivery of veterinary healthcare and the potential for reduced health-seeking behaviour.MethodsElectronic patient re... Read More about A study of the impact of the COVID-19 pandemic on equine veterinary care in the UK.