All Outputs (112)

The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control
Journal Article
Zieger, U., Marston, D. A., Sharma, R., Chikweto, A., Tiwari, K., Sayyid, M., Louison, B., Goharriz, H., Voller, K., Breed, A. C., Werling, D., Fooks, A. R., & Horton, D. L. (in press). The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control. PLoS Neglected Tropical Diseases, 8(10), e3251. https://doi.org/10.1371/journal.pntd.0003251

In Grenada, West Indies, rabies is endemic, and is thought to be maintained in a wildlife host, the small Indian mongoose (Herpestes auropunctatus) with occasional spillover into other hosts. Therefore, the present study was undertaken to improve und... Read More about The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control.

Lack of Genetic Diversity in Newly Sequenced Porcine Circovirus Type 1 Strains Isolated 20 Years Apart
Journal Article
Tombacz, K., Patterson, R., Grierson, S. S., & Werling, D. (in press). Lack of Genetic Diversity in Newly Sequenced Porcine Circovirus Type 1 Strains Isolated 20 Years Apart. Genome Announcements, 2(2), e00156-14. https://doi.org/10.1128/genomeA.00156-14

The complete genome sequences of a porcine circovirus type 1 (PCV1) strain isolated in 1990 and one isolated in 2011 were obtained and compared to the sequences of other available PCV1 isolates. Phylogenetic analyses revealed very low genetic diversi... Read More about Lack of Genetic Diversity in Newly Sequenced Porcine Circovirus Type 1 Strains Isolated 20 Years Apart.

Correlation of cell surface marker expression with African swine fever virus infection
Journal Article
Lithgow, P., Takamatsu, H. H., Werling, D., Dixon, L., & Chapman, D. Correlation of cell surface marker expression with African swine fever virus infection. Veterinary Microbiology, 168(2-4), 413-419. https://doi.org/10.1016/j.vetmic.2013.12.001

Functional characterisation of bovine TLR5 indicates species-specific recognition of flagellin
Journal Article
Metcalfe, H. J., La Ragione, R. M., Smith, D. G. E., & Werling, D. Functional characterisation of bovine TLR5 indicates species-specific recognition of flagellin. Veterinary Immunology and Immunopathology, 157(3-4), 197-205. https://doi.org/10.1016/j.vetimm.2013.12.006

Replacement of two aminoacids in the bovine Toll-like receptor 5 TIR domain with their human counterparts partially restores functional response to flagellin
Journal Article
Osvaldova, A., Woodman, S., Patterson, N. J., Offord, V., Mwangi, D., Gibson, A. J., Matiasovic, J., & Werling, D. Replacement of two aminoacids in the bovine Toll-like receptor 5 TIR domain with their human counterparts partially restores functional response to flagellin. Developmental and Comparative Immunology, 47(1), 90-94. https://doi.org/10.1016/j.dci.2014.07.002

Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium
Journal Article
Schmitz, S., Henrich, M., Neiger, R., Werling, D., & Allenspach, K. Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium. Scandinavian Journal of Immunology, https://doi.org/10.1111/sji.12186

Of creatures great and small: the advantages of farm animal models in immunology research
Journal Article
Gibson, A. J., Coffey, T., & Werling, D. Of creatures great and small: the advantages of farm animal models in immunology research. Frontiers in Immunology, 4, 124. https://doi.org/10.3389/fimmu.2013.00124

LRRfinder2.0: A webserver for the prediction of leucine-rich repeats.
Journal Article
Offord, V., & Werling, D. LRRfinder2.0: A webserver for the prediction of leucine-rich repeats. Innate Immunity, 19(4), 398-402. https://doi.org/10.1177/1753425912465661

To con protection: TIR-domain containing proteins (Tcp) and innate immune evasion.
Journal Article
Patterson, N. J., & Werling, D. To con protection: TIR-domain containing proteins (Tcp) and innate immune evasion. Veterinary Immunology and Immunopathology, 155(3), 149-154. https://doi.org/10.1016/j.vetimm.2013.06.017

Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs
Journal Article
Schmitz, S., Henrich, M., Neiger, R., Werling, D., & Allenspach, K. Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs. Veterinary Immunology and Immunopathology, 153(1-2), 170-174. https://doi.org/10.1016/j.vetimm.2013.02.014

Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs
Journal Article
Schmitz, S., Hill, S., Werling, D., & Allenspach, K. Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs. Veterinary Immunology and Immunopathology, 151(1-2), 168-172. https://doi.org/10.1016/j.vetimm.2012.10.009

Effectiveness of porcine circovirus type 2 vaccination in reducing the severity of post-weaning multisystemic wasting syndrome in pigs
Journal Article
Velasova, M., Alarcon, P., Werling, D., Nevel, M., & Wieland, B. Effectiveness of porcine circovirus type 2 vaccination in reducing the severity of post-weaning multisystemic wasting syndrome in pigs. https://doi.org/10.1016/j.tvjl.2013.05.043

Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1
Journal Article
Willcocks, S., Offord, V., Seyfert, H. M., Coffey, T., & Werling, D. Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1. Journal of Leukocyte Biology, 94(3), 449-58. https://doi.org/10.1189/jlb.0812390

Inhibition of cytosolic phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin
Journal Article
Last, V., Williams, A., & Werling, D. (in press). Inhibition of cytosolic phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin. BMC Neuroscience, 13(1), https://doi.org/10.1186/1471-2202-13-106

Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages
Journal Article
Burr, S., Thomas, C. J., Brownlie, J., Offord, V., Coffey, T. J., & Werling, D. Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages. Veterinary Immunology and Immunopathology, 150(1-2), 123-127. https://doi.org/10.1016/j.vetimm.2012.08.009

Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease
Journal Article
Dakin, S. G., Dudhia, J., Werling, N. J., Werling, D., Abayasekara, D. R. E., & Smith, R. K. W. Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease. PLoS ONE, 7(11), e48978. https://doi.org/10.1371/journal.pone.0048978

Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair
Journal Article
Dakin, S. G., Werling, D., Hibbert, A., Abayasekara, D. R. E., Young, N. J., Smith, R. K. W., & Dudhia, J. Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS ONE, 7(2), e32333. https://doi.org/10.1371/journal.pone.0032333

Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response
Journal Article
Gibson, A. J., Miah, S., Griebel, P., Brownlie, J., & Werling, D. Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response. Developmental and Comparative Immunology, 36(2), 332-341. https://doi.org/10.1016/j.dci.2011.05.002

TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin
Journal Article
Kathrani, A., Holder, A. L., Catchpole, B., Alvarez, L., Simpson, K., Werling, D., & Allenspach, K. TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin. PLoS ONE, 7(1), e30117. https://doi.org/10.1371/journal.pone.0030117

Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex
Journal Article
Pagano, S., Satta, N., Werling, D., Offord, V., DeMoerloose, P., Charbonney, E., Hochstrasser, D., Roux-Lombard, P., & Vuilleumier, N. Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex. Journal of Internal Medicine, 272(4), 344-357. https://doi.org/10.1111/j.1365-2796.2012.02530.x