All Outputs (3)

Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro (2025)
Journal Article
Ritson, M., Xia, D., Wheeler‐Jones, C., & Stolp, H. B. (2025). Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro. Journal of Neurochemistry, 169(6), e70130. https://doi.org/10.1111/jnc.70130

The mechanism by which chronic systemic inflammation contributes to cerebral endothelial dysfunction and neurological disorders is unclear, although endothelial inflammatory signalling is considered a cornerstone of this process. Here, we have perfor... Read More about Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro.

Single-cell transcriptome conservation in a multispecies comparative analysis of fresh and cryopreserved insulinoma cell lines (2025)
Journal Article
Buishand, F. O., Chan, P. Y. K., Xia, D., & Davison, L. J. (2025). Single-cell transcriptome conservation in a multispecies comparative analysis of fresh and cryopreserved insulinoma cell lines. Veterinary Oncology, 2(1), https://doi.org/10.1186/s44356-025-00025-4

Background Insulinoma is the most common pancreatic neuroendocrine tumour in dogs and humans. The understanding of driving factors and critical survival genes in insulinomas is limited and overall survival is poor for canine and human malignant insul... Read More about Single-cell transcriptome conservation in a multispecies comparative analysis of fresh and cryopreserved insulinoma cell lines.

Impact of commercial gut health interventions on caecal metagenome and broiler performance (2025)
Journal Article
Pangga, G., Star-Shirko, B., Psifidi, A., Xia, D., Corcionivoschi, N., Kelly, C., Hughes, C., Lavery, U., Richmond, A., Ijaz, U., & Gundogdu, O. (2025). Impact of commercial gut health interventions on caecal metagenome and broiler performance. Microbiome, 13(1), https://doi.org/10.1186/s40168-024-02012-7

BackgroundMaintaining gut health is a persistent and unresolved challenge in the poultry industry. Given the critical role of gut health in chicken performance and welfare, there is a pressing need to identify effective gut health intervention (GHI)... Read More about Impact of commercial gut health interventions on caecal metagenome and broiler performance.