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All Outputs (10)

Evaluation of subchondral bone cysts in canine elbows with radiographic osteoarthritis secondary to elbow dysplasia (2023)
Journal Article
Jones, G., Gosby, M., May, E., & Meeson, R. (2023). Evaluation of subchondral bone cysts in canine elbows with radiographic osteoarthritis secondary to elbow dysplasia. Veterinary Surgery, https://doi.org/10.1111/vsu.14047

Objective: To investigate whether subchondral bone cysts (SBCs) were present in dogs with radiographic elbow osteoarthritis (OA) and to investigate their relationship with radiographic OA severity.Study design: Retrospective cross-sectional study.Sam... Read More about Evaluation of subchondral bone cysts in canine elbows with radiographic osteoarthritis secondary to elbow dysplasia.

A case series of 37 surgically managed, paraplegic, deep pain negative, French bulldogs with thoracolumbar intervertebral disc extrusion from two English referral centres (2023)
Journal Article
Jones, G., Cherubini, G., Llabres-Diaz, F., Caine, A., & De Stefani, A. (in press). A case series of 37 surgically managed, paraplegic, deep pain negative, French bulldogs with thoracolumbar intervertebral disc extrusion from two English referral centres. Veterinary Record Open, https://doi.org/10.1002/vro2.61

Background: Thoracolumbar intervertebral disc extrusions (TL-IVDE) are a common spinal disorder in dogs, especially within chondrodystrophic breeds. Loss of deep nociception is a well-documented negative prognostic indicator in dogs with TL-IVDE, wi... Read More about A case series of 37 surgically managed, paraplegic, deep pain negative, French bulldogs with thoracolumbar intervertebral disc extrusion from two English referral centres.

A new method for segmentation and analysis of bone callus in rodent fracture models using micro-CT (2022)
Journal Article
Hopkinson, M., Jones, G., Evans, L., Gohin, S., Magnusdottir, R., Salmon, P., …Pitsillides, A. (2022). A new method for segmentation and analysis of bone callus in rodent fracture models using micro-CT. Journal of Orthopaedic Research, https://doi.org/10.1002/jor.25507

Fracture burden has created a need to better understand bone repair processes under different pathophysiological states. Evaluation of structural and material properties of the mineralized callus, which is integral to restoring biomechanical stabilit... Read More about A new method for segmentation and analysis of bone callus in rodent fracture models using micro-CT.

Moving beyond the limits of detection: the past, the present, and the future of diagnostic imaging in canine osteoarthritis (2022)
Journal Article
Jones, G., Pitsillidies, A., & Meeson, R. (2022). Moving beyond the limits of detection: the past, the present, and the future of diagnostic imaging in canine osteoarthritis. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2022.789898

Osteoarthritis (OA) is the most common orthopaedic condition in dogs, characterised as chronic, painful end-point of a synovial joint with limited therapeutic options other than palliative pain control or surgical salvage. Since the 1970s, radiograph... Read More about Moving beyond the limits of detection: the past, the present, and the future of diagnostic imaging in canine osteoarthritis.

Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs (2022)
Journal Article
Fentem, R., de Stefani, A., Quintana, R., Alcoverro, E., Jones, G., Amengual-Batle, P., & Goncalves, R. (2022). Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16353

Background Status epilepticus (SE) is an emergency associated with serious consequences for both patient and owner. Data regarding risk factors for short-term mortality or recurrence in dogs with SE is limited. Objective Identify risk factors associa... Read More about Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs.

Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists (2021)
Journal Article
Jones, G., Volk, H., & Packer, R. (in press). Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16144

Background: Epilepsy is the most common chronic neurological disease in dogs that impacts the quality of life (QoL) of affected dogs and their owners. Canine epilepsy research is expanding internationally, but where best to focus limited research tim... Read More about Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists.

Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185 (2018)
Journal Article
Holder, A. L., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R., & Catchpole, B. (2018). Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185. Developmental and Comparative Immunology, 81, 244-251. https://doi.org/10.1016/j.dci.2017.12.008

Interleukin-7 (IL-7) and its receptor (IL-7R) are essential for T cell development in the thymus, and changes in the IL-7/IL-7R pathway have been implicated in age-associated thymic involution which results in a reduction of naïve T cell output. The... Read More about Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185.