Browse

Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists (2021)
Journal Article
Jones, G., Volk, H., & Packer, R. (in press). Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16144

Background: Epilepsy is the most common chronic neurological disease in dogs that impacts the quality of life (QoL) of affected dogs and their owners. Canine epilepsy research is expanding internationally, but where best to focus limited research tim... Read More about Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists.

Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells (2021)
Journal Article
Regan, J., Mirczuk, S., Scudder, C., Stacey, E., Khan, S., Powles, T., …Fowkes, R. (2021). Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells. Cells, https://doi.org/10.3390/cells10020398

C-type natriuretic peptide (CNP) is the major natriuretic peptide of the central nervous system and acts via its selective guanylyl cyclase-B (GC-B) receptor to regulate cGMP production in neurons, astrocytes and endothelial cells. CNP is implicated... Read More about Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells.

Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors (2021)
Journal Article
Mirczuk, S., Scudder, C., Read, J., Crossley, V., Regan, J., Richardson, K., …Fowkes, R. (2021). Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors. International Journal of Molecular Sciences, -. https://doi.org/10.3390/ijms22031076

Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP; NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes; loss-of-function mutations cause achondroplasia, whereas gain-of-function mut... Read More about Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors.