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Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites
Journal Article
Platt, R. N., McDew-White, M., Le Clec'H, W., Chevalier, F. D., Allan, F., Emery, A. M., Garba, A., Hamidou, A. A., Ame, S. M., Webster, J. P., Rollinson, D., Webster, B. L., & Anderson, T. J. C. (in press). Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites. Molecular Biology and Evolution, 36(10), 2127-2142. https://doi.org/10.1093/molbev/msz154

Introgression among parasite species has the potential to transfer traits of biomedical importance across species boundaries. The parasitic blood fluke Schistosoma haematobium causes urogenital schistosomiasis in humans across sub-Saharan Africa. Hyb... Read More about Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites.

Plagiorchis sp. in small mammals of Senegal and the potential emergence of a zoonotic trematodiasis
Journal Article
Catalano, S., Nadler, S. A., Fall, C. B., Marsh, K. J., Léger, E., Sène, M., Priestnall, S. L., Wood, C. L., Diouf, N. D., Bâ, K., & Webster, J. P. (in press). Plagiorchis sp. in small mammals of Senegal and the potential emergence of a zoonotic trematodiasis. International Journal for Parasitology, 8, 164-170. https://doi.org/10.1016/j.ijppaw.2019.02.003

Trematodes of the genus Plagiorchis have a wide geographical distribution and can exploit a variety of hosts. The occurrence and zoonotic potential of Plagiorchis spp. have been characterised across several countries in Asia; in contrast, information... Read More about Plagiorchis sp. in small mammals of Senegal and the potential emergence of a zoonotic trematodiasis.

Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective
Journal Article
Mutombo, P. N., Man, N. W. Y., Nejsum, P., Ricketson, R., Gordon, C. A., Robertson, G., Clements, A. C. A., Chacon-Fonseca, N., Nissapatorn, V., Webster, J. P., & McLaws, M.-L. Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective. https://doi.org/10.1016/bs.apar.2019.02.004

Soil-transmitted helminth (STH) infections represent a major public health problem globally, particularly among socio-economically disadvantaged populations. Detection of STH infections is often challenging, requiring a combination of diagnostic tech... Read More about Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective.

Epidemiological interactions between urogenital and intestinal human schistosomiasis in the context of praziquantel treatment across three West African countries
Journal Article
Knowles, S. C. L., Webster, B. L., Garba, A., Sacko, M., Diaw, O. T., Fenwick, A., Rollinson, D., & Webster, J. P. (in press). Epidemiological interactions between urogenital and intestinal human schistosomiasis in the context of praziquantel treatment across three West African countries. PLoS Neglected Tropical Diseases, 9(10), https://doi.org/10.1371/journal.pntd.0004019

A Latent Markov Modelling Approach to the Evaluation of Circulating Cathodic Antigen Strips for Schistosomiasis Diagnosis Pre- and Post-Praziquantel Treatment in Uganda
Journal Article
Koukounari, A., Donnelly, C. A., Moustaki, I., Tukahebwa, E. M., Kabatereine, N. B., Wilson, S., Webster, J. P., Deelder, A. M., Vennervald, B. J., & van Dam, G. J. A Latent Markov Modelling Approach to the Evaluation of Circulating Cathodic Antigen Strips for Schistosomiasis Diagnosis Pre- and Post-Praziquantel Treatment in Uganda. PLoS Computational Biology, 9(12), https://doi.org/10.1371/journal.pcbi.1003402

Analysis of the population genetics of Opisthorchis viverrini sensu lato in the Nam Ngum River wetland, Lao PDR, by multilocus enzyme electrophoresis
Journal Article
Kiatsopit, N., Sithithaworn, P., Saijuntha, W., Pitaksakulrat, O., Petney, T. N., Webster, J. P., & Andrews, R. H. Analysis of the population genetics of Opisthorchis viverrini sensu lato in the Nam Ngum River wetland, Lao PDR, by multilocus enzyme electrophoresis. Parasitology Research, 113(8), 2973-2981. https://doi.org/10.1007/s00436-014-3959-9

Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition
Journal Article
French, M. D., Churcher, T. S., Basáñez, M.-G., Norton, A. J., Lwambo, N. J. S., & Webster, J. P. Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition. Acta Tropica, 128(2), 196-205. https://doi.org/10.1016/j.actatropica.2012.03.001

Detecting potential changes in genetic diversity in schistosome populations following chemotherapy with praziquantel (PZQ) is crucial if we are to fully understand the impact of such chemotherapy with respect to the potential emergence of resistance... Read More about Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition.

Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger
Journal Article
Garba, A., Lamine, M. S., Barkire, N., Djibo, A., Sofo, B., Gouvras, A. N., Labbo, R., Sebangou, H., Webster, J. P., Fenwick, A., & Utzinger, J. Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger. Acta Tropica, 128(2), 334-344. https://doi.org/10.1016/j.actatropica.2012.08.008