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Epidemiological interactions between urogenital and intestinal human schistosomiasis in the context of praziquantel treatment across three West African countries
Journal Article
Knowles, S. C. L., Webster, B. L., Garba, A., Sacko, M., Diaw, O. T., Fenwick, A., Rollinson, D., & Webster, J. P. (in press). Epidemiological interactions between urogenital and intestinal human schistosomiasis in the context of praziquantel treatment across three West African countries. PLoS Neglected Tropical Diseases, 9(10), https://doi.org/10.1371/journal.pntd.0004019

DEVELOPMENT OF NOVEL MULTIPLEX MICROSATELLITE POLYMERASE CHAIN REACTIONS TO ENABLE HIGH-THROUGHPUT POPULATION GENETIC STUDIES OF SCHISTOSOMA HAEMATOBIUM (VOL 8, 432, 2015)
Journal Article
Webster, B. L., Rabone, M., Pennance, T., Emery, A. M., Allan, F., Gouvras, A., Knopp, S., Garba, A., Hamidou, A. A., Mohammed, K. A., Ame, S. M., Rollinson, D., & Webster, J. P. DEVELOPMENT OF NOVEL MULTIPLEX MICROSATELLITE POLYMERASE CHAIN REACTIONS TO ENABLE HIGH-THROUGHPUT POPULATION GENETIC STUDIES OF SCHISTOSOMA HAEMATOBIUM (VOL 8, 432, 2015). https://doi.org/10.1186/s13071-015-1134-5

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment
Journal Article
Chevalier, F. D., Le Clec’h, W., McDew-White, M., Menon, V., Guzman, M. A., Holloway, S. P., Cao, X., Taylor, A. B., Kinung'Hi, S., Gouvras, A. N., Webster, B. L., Webster, J. P., Emery, A. M., Rollinson, D., Garba Djirmay, A., Al Mashikhi, K. M., Al Yafae, S., Idris, M. A., Moné, H., Mouahid, G., …Anderson, T. J. C. (in press). Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment. PLoS Pathogens, 15(10), https://doi.org/10.1371/journal.ppat.1007881

Do mutations required for adaptation occur de novo, or are they segregating within populations as standing genetic variation? This question is key to understanding adaptive change in nature, and has important practical consequences for the evolution... Read More about Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.

Analysis of the population genetics of Opisthorchis viverrini sensu lato in the Nam Ngum River wetland, Lao PDR, by multilocus enzyme electrophoresis
Journal Article
Kiatsopit, N., Sithithaworn, P., Saijuntha, W., Pitaksakulrat, O., Petney, T. N., Webster, J. P., & Andrews, R. H. Analysis of the population genetics of Opisthorchis viverrini sensu lato in the Nam Ngum River wetland, Lao PDR, by multilocus enzyme electrophoresis. Parasitology Research, 113(8), 2973-2981. https://doi.org/10.1007/s00436-014-3959-9

Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition
Journal Article
French, M. D., Churcher, T. S., Basáñez, M.-G., Norton, A. J., Lwambo, N. J. S., & Webster, J. P. Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition. Acta Tropica, 128(2), 196-205. https://doi.org/10.1016/j.actatropica.2012.03.001

Detecting potential changes in genetic diversity in schistosome populations following chemotherapy with praziquantel (PZQ) is crucial if we are to fully understand the impact of such chemotherapy with respect to the potential emergence of resistance... Read More about Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition.

Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger
Journal Article
Garba, A., Lamine, M. S., Barkire, N., Djibo, A., Sofo, B., Gouvras, A. N., Labbo, R., Sebangou, H., Webster, J. P., Fenwick, A., & Utzinger, J. Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger. Acta Tropica, 128(2), 334-344. https://doi.org/10.1016/j.actatropica.2012.08.008

Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: Implications for epidemiology, evolution and control
Journal Article
Gower, C. M., Gouvras, A. N., Lamberton, P. H. L., Deol, A., Shrivastava, J., Mutombo, P. N., Mbuh, J. V., Norton, A. J., Webster, B. L., Stothard, J. R., Garba, A., Lamine, M. S., Kariuki, C., Lange, C. N., Mkoji, G. M., Kabatereine, N. B., Gabrielli, A. F., Rudge, J. W., Fenwick, A., Sacko, M., …Webster, J. P. Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: Implications for epidemiology, evolution and control. Acta Tropica, 128(2), 261-274. https://doi.org/10.1016/j.actatropica.2012.09.014

A Latent Markov Modelling Approach to the Evaluation of Circulating Cathodic Antigen Strips for Schistosomiasis Diagnosis Pre- and Post-Praziquantel Treatment in Uganda
Journal Article
Koukounari, A., Donnelly, C. A., Moustaki, I., Tukahebwa, E. M., Kabatereine, N. B., Wilson, S., Webster, J. P., Deelder, A. M., Vennervald, B. J., & van Dam, G. J. A Latent Markov Modelling Approach to the Evaluation of Circulating Cathodic Antigen Strips for Schistosomiasis Diagnosis Pre- and Post-Praziquantel Treatment in Uganda. PLoS Computational Biology, 9(12), https://doi.org/10.1371/journal.pcbi.1003402