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Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa (2022)
Journal Article
Papoutsopoulou, S., Tang, J., Elramli, A. H., Williams, J. M., Gupta, N., Ikuomola, F. I., …Pritchard, D. M. (2022). Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa. American Journal of Physiology - Gastrointestinal and Liver Physiology, 323(4), G306-G317. https://doi.org/10.1152/ajpgi.00037.2022

Background & aims: The alternative (non-canonical) nuclear factor-kB (NF-kB) signalling pathway predominantly regulates the function of the p52/RelB heterodimer. Germline Nfkb2 deficiency in mice leads to loss of p100/p52 protein and offers protectio... Read More about Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa.

Interleukin-10 Deficiency Impacts on TNF-Induced NFκB Regulated Responses In Vivo (2022)
Journal Article
Papoutsopoulou, S., Pollock, L., Williams, J. M., Abdul-Mahdi, M. M. L. F., Dobbash, R., Duckworth, C. A., & Campbell, B. J. (in press). Interleukin-10 Deficiency Impacts on TNF-Induced NFκB Regulated Responses In Vivo. Biology, 11(10), 1377. https://doi.org/10.3390/biology11101377

Interleukin-10 (IL-10) is an anti-inflammatory cytokine that has a major protective role against intestinal inflammation. We recently revealed that intestinal epithelial cells in vitro regulate NFκB-driven transcriptional responses to TNF via an auto... Read More about Interleukin-10 Deficiency Impacts on TNF-Induced NFκB Regulated Responses In Vivo.

Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with Eimeria (2022)
Journal Article
Williams, J., Blake, D., & Xia, D. (2022). Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with Eimeria. Avian Pathology, https://doi.org/10.1080/03079457.2022.2076581

Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with Eimeria