A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease

Jiang, Jiahao; Hiron, Thomas K.; Agbaedeng, Thomas; Malhotra, Yashaswat; Drydale, Edward; Bancroft, James; Ng, Esther; Reschen, Michael E.; Davison, Lucy J.; O’Callaghan, Chris A.

doi:10.1161/circresaha.123.324172

All Outputs (4)

Transcriptomic analysis reveals a critical role for activating Gsα mutations in spontaneous feline hyperthyroidism (2024)
Journal Article
Hiron, T. K., Aguiar, J., Williams, J. M., Falcone, S., Norman, P. A., Elliott, J., Fowkes, R. C., Syme, H. M., & Davison, L. J. (in press). Transcriptomic analysis reveals a critical role for activating Gsα mutations in spontaneous feline hyperthyroidism. Scientific Reports, 14(1), https://doi.org/10.1038/s41598-024-79564-z

Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes (2024)
Journal Article
Hill, T. G., Gao, R., Benrick, A., Kothegala, L., Rorsman, N., Santos, C., Acreman, S., Briant, L. J., Dou, H., Gandasi, N. R., Guida, C., Haythorne, E., Wallace, M., Knudsen, J. G., Miranda, C., Tolö, J., Clark, A., Davison, L., Størling, J., Tarasov, A., …Zhang, Q. (2024). Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes. Nature Metabolism, https://doi.org/10.1038/s42255-024-01139-z

Exocrine pancreatic inflammation in canine diabetes mellitus – an active offender? (2024)
Journal Article
Johnson-Pitt, A., Catchpole, B., & Davison, L. J. (in press). Exocrine pancreatic inflammation in canine diabetes mellitus – an active offender?. The Veterinary Journal, 106241. https://doi.org/10.1016/j.tvjl.2024.106241

A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease (2024)
Journal Article
Jiang, J., Hiron, T. K., Agbaedeng, T., Malhotra, Y., Drydale, E., Bancroft, J., Ng, E., Reschen, M. E., Davison, L. J., & O’Callaghan, C. A. (2024). A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease. Circulation Research, 135(1), 6-25. https://doi.org/10.1161/circresaha.123.324172

BACKGROUND:

Coronary artery disease (CAD), the leading cause of death worldwide, is influenced by both environmental and genetic factors. Although over 250 genetic risk loci have been identified through genome-wide association studies, the specifi... Read More about A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease.