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All Outputs (6)

Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida. (2025)
Journal Article
Hughes, A., Pelligand, L., Andersson, D., & Mead, A. (2025). Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida. PLoS ONE, https://doi.org/10.1371/journal.pone.0327115

Antimicrobial resistance is a global threat to both human and animal health, and transfer of resistance between these spheres is recognised as a key concern for all species. Selection for resistance at sub-inhibitory antimicrobial concentrations has... Read More about Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida..

Validation and evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers (2025)
Journal Article
Hedges, S., Mompelat, S., Hurtaud-Pessel, D., Blake, D., Fournié, G., & Pelligand, L. (2025). Validation and evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.70000

Persistence of antimicrobial drugs (AMDs) administered to poultry is longer in feathers than in edible tissues. Hence poultry feathers are a suitable matrix to investigate historical exposure contributing to antimicrobial resistance, since current de... Read More about Validation and evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers.

Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing (2025)
Journal Article
Pelligand, L., Toutain, P.-L., Bouquet-Mélou, A., Ferran, A., Roques, B., del Castillo, J., Lees, P., Croubels, S., & Bousquet, E. (2025). Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13511

This meta-analysis provides a population model of doxycycline (DOXY) disposition in pigs for computation of PK/PD cutoff values corresponding to differing modalities of DOXY administration orally in pigs. This analysis enables establishment of specif... Read More about Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing.

Erreurs en anesthésie : enquête et analyse de pratique un jour au bloc opératoire en France (2025)
Journal Article
Fuzier, R., Bordes, J., Basquin, C., Bordes-Demolis, M., Bourgain, J.-L., Campion, S., Fletcher, D., Morau, E., Pelieu, I., Pelligand, L., San Miguel, A., Soufir, L., Untereiner, O., Vacheron, C.-H., Blanié, A., & Picard, J. (online). Erreurs en anesthésie : enquête et analyse de pratique un jour au bloc opératoire en France. Anesthésie & Réanimation, https://doi.org/10.1016/j.anrea.2024.11.003

Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens (2025)
Journal Article
Mead, A., Hughes, A., Azzariti, S., Toutain, P.-L., & Pelligand, L. (2025). Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13500

This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae, and Pasteurella multocida. In vitro time-kill assays and... Read More about Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens.