All Outputs (2)

Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton (2024)
Journal Article
Bourne, L., Jayash, S., Michels, L., Hopkinson, M., Guppy, F., Clarkin, C., Gard, P., Brissett, N., & Staines, K. (2024). Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton. Biology of Sex Differences, 15(1), https://doi.org/10.1186/s13293-024-00626-y

Background Prenatal alcohol exposure (PAE) can result in lifelong disabilities known as foetal alcohol spectrum disorder (FASD) and is associated with childhood growth deficiencies and increased bone fracture risk. However, the effects of PAE on the... Read More about Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton.

Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response (2024)
Journal Article
Corsiero, E., Caliste, M., Jagemann, L., Fossati-Jimack, L., Goldmann, K., Cubuk, C., Ghirardi, G., Prediletto, E., Rivellese, F., Alessandri, C., Hopkinson, M., Javaheri, B., Pitsillides, A., Lewis, M., Pitzalis, C., & Bombardieri, M. (2024). Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response. Journal of Clinical Investigation, 134(12), https://doi.org/10.1172/JCI169754

Ectopic lymphoid structures (ELSs) in the rheumatoid synovial joints sustain autoreactivity against locally expressed autoantigens. We recently identified recombinant monoclonal antibodies (RA-rmAbs) derived from single, locally differentiated rheuma... Read More about Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response.