All Outputs (3)

A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence (2020)
Journal Article
Surakhy, M., Wallace, M., Bond, E., Grochola, L. F., Perez, H., Di Giovannantonio, M., …Bond, G. L. (2020). A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence. British Journal of Cancer, 122(8), 1231-1241. https://doi.org/10.1038/s41416-020-0764-3

Venous identity requires BMP signalling through ALK3 (2019)
Journal Article
Neal, A., Nornes, S., Payne, S., Wallace, M. D., Fritzsche, M., Louphrasitthiphol, P., …De Val, S. (2019). Venous identity requires BMP signalling through ALK3. Nature Communications, 10(1), https://doi.org/10.1038/s41467-019-08315-w

Venous endothelial cells are molecularly and functionally distinct from their arterial counterparts. Although veins are often considered the default endothelial state, genetic manipulations can modulate both acquisition and loss of venous fate, sugge... Read More about Venous identity requires BMP signalling through ALK3.

The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice (2016)
Journal Article
Kartha, N., Shen, L., Maskin, C., Wallace, M., & Schimenti, J. C. (2016). The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice. Genetics, 203(4), 1601-1611. https://doi.org/10.1534/genetics.115.184879

Human cancer genome studies have identified the SWI/SNF chromatin remodeling complex member ARID1A as one of the most frequently altered genes in several tumor types. Its role as an ovarian tumor suppressor has been supported in compound knockout mic... Read More about The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice.