The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice
(2016)
Journal Article
Kartha, N., Shen, L., Maskin, C., Wallace, M., & Schimenti, J. C. (2016). The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice. Genetics, 203(4), 1601-1611. https://doi.org/10.1534/genetics.115.184879
Human cancer genome studies have identified the SWI/SNF chromatin remodeling complex member ARID1A as one of the most frequently altered genes in several tumor types. Its role as an ovarian tumor suppressor has been supported in compound knockout mic... Read More about The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice.