All Outputs (124)

Comparison of standardised versus non-standardised methods for testing the in vitro potency of oxytetracycline against mannheimia haemolytica and pasteurella multocida (2016)
Journal Article
Lees, P., Illambas, J., Pelligand, L., & Toutain, P. L. (2016). Comparison of standardised versus non-standardised methods for testing the in vitro potency of oxytetracycline against mannheimia haemolytica and pasteurella multocida. https://doi.org/10.1016/j.tvjl.2016.11.006

Activity of florfenicol for Actinobacillus pleuropneumoniae and Pasteurella multocida using standardised versus non-standardised methodology (2016)
Journal Article
Dorey, L., Hobson, S., & Lees, P. (2016). Activity of florfenicol for Actinobacillus pleuropneumoniae and Pasteurella multocida using standardised versus non-standardised methodology. https://doi.org/10.1016/j.tvjl.2016.11.004

Veterinary Medicine Needs New Green Antimicrobial Drugs (2016)
Journal Article
Toutain, P. L., Ferran, A. A., Bousquet-Mélou, A., Pelligand, L., & Lees, P. (2016). Veterinary Medicine Needs New Green Antimicrobial Drugs. Frontiers in Microbiology, 7, 1196. https://doi.org/10.3389/fmicb.2016.01196

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney (2015)
Journal Article
Pelligand, L., Suemanotham, N., King, J. N., Seewald, W., Syme, H. M., Smith, K. C., Lees, P., & Elliott, J. (2015). Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC Veterinary Research, 11(296), https://doi.org/10.1186/s12917-015-0598-z

Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation (2014)
Journal Article
Pelligand, L., King, J. N., Hormazabal, V., Toutain, P. L., Elliott, J., & Lees, P. (2014). Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation. Journal of Veterinary Pharmacology and Therapeutics, 37(4), 354-366. https://doi.org/10.1111/jvp.12107

Robenacoxib and ketoprofen are acidic nonsteroidal anti‐inflammatory drugs (NSAIDs). Both are licensed for once daily administration in the cat, despite having short blood half‐lives. This study reports the pharmacokinetic/pharmacodynamic (PK/PD) mod... Read More about Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation.

Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves (2013)
Journal Article
Brentnall, C., Cheng, Z. R., McKellar, Q. A., & Lees, P. (2013). Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves. Journal of Veterinary Pharmacology and Therapeutics, 36(4), 320-328. https://doi.org/10.1111/jvp.12000

A tissue cage model of inflammation in calves was used to determine the pharmacokinetic and pharmacodynamic properties of individual carprofen enantiomers, following the administration of the racemate. RS(±) carprofen was administered subcutaneously... Read More about Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves.

Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in goats
Journal Article
Sidhu, P. K., Landoni, M. F., Aliabadi, F. S., & Lees, P. Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in goats. https://doi.org/10.1016/j.tvjl.2009.02.009

Safety of oral robenacoxib in the cat
Journal Article
King, J. N., Hotz, R., Reagan, E. L., Roth, D. R., Seewald, W., & Lees, P. Safety of oral robenacoxib in the cat. Journal of Veterinary Pharmacology and Therapeutics, 35(3), 290-300. https://doi.org/10.1111/j.1365-2885.2011.01320.x

PK-PD integration and modeling of marbofloxacin in sheep
Journal Article
Sidhu, P. K., Landoni, M. F., Aliabadi, F. S., & Lees, P. PK-PD integration and modeling of marbofloxacin in sheep. Research in Veterinary Science, 88(1), 134-141. https://doi.org/10.1016/j.rvsc.2009.05.013

Analgesic and anti-inflammatory actions of robenacoxib in acute joint inflammation in dog
Journal Article
Schmid, V. B., Spreng, D. E., Seewald, W., Jung, M., Lees, P., & King, J. N. Analgesic and anti-inflammatory actions of robenacoxib in acute joint inflammation in dog. Journal of Veterinary Pharmacology and Therapeutics, 33(2), 118-131. https://doi.org/10.1111/j.1365-2885.2009.01117.x

In vitro and ex vivo inhibition of COX isoforms by robenacoxib in the cat: a comparative study
Journal Article
Schmid, V. B., Seewald, W., Lees, P., & King, J. N. In vitro and ex vivo inhibition of COX isoforms by robenacoxib in the cat: a comparative study. Journal of Veterinary Pharmacology and Therapeutics, 33(5), 444-452. https://doi.org/10.1111/j.1365-2885.2010.01166.x

INTEGRATION OF PHARMACOKINETIC AND PHARMACODYNAMIC DATA FOR FLORFENICOL IN CALVES
Presentation / Conference Contribution
Potter, T. J., Illambas, J., Sidhu, P. K., Rassouli, A., Rycroft, A. N., & Lees, P. INTEGRATION OF PHARMACOKINETIC AND PHARMACODYNAMIC DATA FOR FLORFENICOL IN CALVES

In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: A comparative study
Journal Article
King, J. N., Rudaz, C., Borer, L., Jung, M., Seewald, W., & Lees, P. In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: A comparative study. Research in Veterinary Science, 88(3), 497-506. https://doi.org/10.1016/j.rvsc.2009.11.002

Determination of a dosage regimen of colistin by pharmacokinetic/pharmacodynamic integration and modeling for treatment of GIT disease in pigs
Journal Article
Guyonnet, J., Manco, B., Baduel, L., Kaltsatos, V., Aliabadi, M. H. S., & Lees, P. Determination of a dosage regimen of colistin by pharmacokinetic/pharmacodynamic integration and modeling for treatment of GIT disease in pigs. Research in Veterinary Science, 88(2), 307-314. https://doi.org/10.1016/j.rvsc.2009.09.001

From Materia Medica to veterinary pharmacology and therapeutics. Introduction
Book Chapter
Cunningham, F. M., Elliott, J., & Lees, P. From Materia Medica to veterinary pharmacology and therapeutics. Introduction. . https://doi.org/10.1007/978-3-642-10324-7_1

Comparative and Veterinary Pharmacology Introduction
Book Chapter
Cunningham, F. M., Elliott, J., & Lees, P. Comparative and Veterinary Pharmacology Introduction. . https://doi.org/10.1007/978-3-642-10324-7_1

Age-related differences in prostaglandin E-2 synthesis by equine cartilage explants and synoviocytes
Journal Article
Briston, L., Dudhia, J., & Lees, P. Age-related differences in prostaglandin E-2 synthesis by equine cartilage explants and synoviocytes. Journal of Veterinary Pharmacology and Therapeutics, 33(3), 268-276. https://doi.org/10.1111/j.1365-2885.2009.01131.x

Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in calves
Journal Article
Sidhu, P. K., Landoni, M. F., Aliabadi, M. H. S., Toutain, P. L., & Lees, P. Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in calves. Journal of Veterinary Pharmacology and Therapeutics, 34(4), 376-387. https://doi.org/10.1111/j.1365-2885.2010.01247.x

Determination of minimum inhibitory and minimum bactericidal concentrations of tiamulin against field isolates of Actinobacillus pleuropneumoniae
Journal Article
Pridmore, A., Burch, D., & Lees, P. Determination of minimum inhibitory and minimum bactericidal concentrations of tiamulin against field isolates of Actinobacillus pleuropneumoniae. Veterinary Microbiology, 151(3-4), 409-412. https://doi.org/10.1016/j.vetmic.2011.03.016

Pharmacokinetics and bioequivalence in the pig of two ivermectin feed formulations
Journal Article
Lees, P., Cheng, Z. R., Chambers, M., Speirs, G., Hennessy, D., & Abbott, E. M. Pharmacokinetics and bioequivalence in the pig of two ivermectin feed formulations. Journal of Veterinary Pharmacology and Therapeutics, 36(4), 350-357. https://doi.org/10.1111/j.1365-2885.2012.01428.x