All Outputs (3)

Hormonal Regulation of Glucocorticoid Inactivation and Reactivation in aT3-1 and LßT2 Gonadotroph Cells (2019)
Journal Article
Michael, A. E., Thurston, L. M., & Fowkes, R. C. (2019). Hormonal Regulation of Glucocorticoid Inactivation and Reactivation in aT3-1 and LßT2 Gonadotroph Cells. Biology, 8(4), 81. https://doi.org/10.3390/biology8040081

The regulation of reproductive function by glucocorticoids occurs at all levels of the hypothalamo-pituitary-gonadal axis. Within the pituitary, glucocorticoids have been shown to directly alter gene expression in gonadotrophs, indicating that these... Read More about Hormonal Regulation of Glucocorticoid Inactivation and Reactivation in aT3-1 and LßT2 Gonadotroph Cells.

What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol (2019)
Journal Article
Packer, R. M. A., Davies, A. M., Volk, H. A., Puckett, H. L., Hobbs, S. L., & Fowkes, R. C. (2019). What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol. PLoS ONE, 14(5), e0216000. https://doi.org/10.1371/journal.pone.0216000

Hair is an emerging biological matrix in which to measure chronic HPA axis activity, offering a longer term view into an animal’s life. We explored effects of exogenous (e.g. lifestyle, medications, social environment) and endogenous (e.g. disease, b... Read More about What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol.

Pituitary pathology and gene expression in acromegalic cats (2019)
Journal Article
Scudder, C. J., Mirczuk, S. M., Richardson, K. M., Crossley, V. J., Regan, J. T. C., Gostelow, R., Forcada, Y., Hazuchova, K., Harrington, N., McGonnell, I. M., Church, D. B., Kenny, P. J., Korbonits, M., Fowkes, R. C., & Niessen, S. J. M. (2019). Pituitary pathology and gene expression in acromegalic cats. Journal of the Endocrine Society, 3(1), 181-200. https://doi.org/10.1210/js.2018-00226

The prevalence of growth hormone secreting pituitary tumours in domestic cats (Felis catus) is ten times greater than in humans. The predominant inhibitory receptors of growth hormone-secreting pituitary tumours are somatostatin receptors (SSTRs) and... Read More about Pituitary pathology and gene expression in acromegalic cats.