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All Outputs (145)

Principles of stem cell therapy in the horse - the science behind the technology
Journal Article
Smith, R. K. W. Principles of stem cell therapy in the horse - the science behind the technology

Tendon and ligament overstrain injuries in the horse are appropriate diseases to consider for stem cell therapy because normal fibrous repair results in reduced functionality, typified by poorer performance and a high rate of re-injury. Exogenously a... Read More about Principles of stem cell therapy in the horse - the science behind the technology.

Stem cell therapy for tendon and ligament injuries in the horse - technique and outcome
Journal Article
Smith, R. K. W. Stem cell therapy for tendon and ligament injuries in the horse - technique and outcome

The technique involves the collection of bone marrow from the sternum in the standing sedated horse, followed by isolation and expansion of the nucleated adherent cell population (containing the MSCs) in the laboratory. After approximately 2-3 weeks,... Read More about Stem cell therapy for tendon and ligament injuries in the horse - technique and outcome.

Diagnostic ultrasound of the limb joints, muscle and bone in horses
Journal Article
Smith, M., & Smith, R. K. W. Diagnostic ultrasound of the limb joints, muscle and bone in horses. In Practice, 30(3), 152-159

DIAGNOSTIC ultrasonography for the musculoskeletal system in the horse was first used in the early 1980s. Initial applications were directed towards the diagnosis of flexor tendon and ligament injuries in the distal limb, but this modality is now com... Read More about Diagnostic ultrasound of the limb joints, muscle and bone in horses.

Regenerative medicine for tendinous and ligamentous injuries of sport horses
Journal Article
Fortier, L. A., & Smith, R. K. W. Regenerative medicine for tendinous and ligamentous injuries of sport horses. https://doi.org/10.1016/j.cveq.2007.11.002

After tendon injury the scar tissue that replaces the damaged tendon results in a substantial risk for reinjury. The goal of regenerative therapies is to restore normal structural architecture and biomechanical function to an injured tissue. Successf... Read More about Regenerative medicine for tendinous and ligamentous injuries of sport horses.

Can exercise modulate the maturation of functionally different immature tendons in the horse?
Journal Article
Kasashima, Y., Takahashi, T., Birch, H. L., Smith, R. K. W., & Goodship, A. E. Can exercise modulate the maturation of functionally different immature tendons in the horse?. Journal of Applied Physiology, 104(2), 416-422. https://doi.org/10.1152/japplphysiol.00379.2007

Tendons can be considered in two functional groups, those contributing to energetics of locomotion and those acting solely to position the limb. The energy-storing tendons in both human and equine athletes have a high frequency of injury with similar... Read More about Can exercise modulate the maturation of functionally different immature tendons in the horse?.

The influence of exercise during growth on ultrasonographic parameters of the superficial digital flexor tendon of young Thoroughbred horses
Journal Article
Moffat, P. A., Firth, E. C., Rogers, C. W., Smith, R. K. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., Mcilwraith, C. W., & Van Weeren, P. R. The influence of exercise during growth on ultrasonographic parameters of the superficial digital flexor tendon of young Thoroughbred horses. Equine Veterinary Journal, 40(2), 136-140. https://doi.org/10.2746/042516408x253109

Reasons for performing study: Conditioning by early training may influence the composition of certain musculoskeletal tissues, but very few data exist on its effect during growth on tendon structure and function.

Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth
Journal Article
Rogers, C. W., Firth, E. C., McIlwraitht, C. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., Smith, R. K. W., & Van Weeren, P. R. Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth. Equine Veterinary Journal, 40(2), 111-118. https://doi.org/10.2746/042516408x268923

Reasons for performing study: No data exist on the intensity of exercise required or on possible harmful effects of increasing exercise in foals over the natural level when free at pasture.

Evaluation of a new strategy to modulate skeletal development in racehorses by imposing track-based exercise during growth: The effects on 2-and 3-year-old racing careers
Journal Article
Rogers, C. W., Firth, E. C., Mcilwraith, C. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., Smith, R. K. W., & Van Weeren, P. R. Evaluation of a new strategy to modulate skeletal development in racehorses by imposing track-based exercise during growth: The effects on 2-and 3-year-old racing careers. Equine Veterinary Journal, 40(2), 119-127. https://doi.org/10.2746/042516408x266088

Reasons for performing study: No data exist on the effects of conditioning exercise at foal age on workload and subsequent clinical injury rate during their 2- and 3-year-old racing careers.

Changes in synovial fluid biomarker concentrations following arthroscopic surgery in horses with osteochondritis dissecans of the distal intermediate ridge of the tibia
Journal Article
Brink, P., Smith, R. K. W., Tverdal, A., & Dolvik, N. I. Changes in synovial fluid biomarker concentrations following arthroscopic surgery in horses with osteochondritis dissecans of the distal intermediate ridge of the tibia. American Journal of Veterinary Research, 76(7), 599-607. https://doi.org/10.2460/ajvr.76.7.599