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All Outputs (7)

Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013) (2017)
Journal Article
Rosanowski, S. M., Chang, Y. M., Stirk, A. J., & Verheyen, K. L. P. (2017). Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013). Preventive Veterinary Medicine, 148, 58-65. https://doi.org/10.1016/j.prevetmed.2017.10.003

The incidence of race-day injuries in Great Britain (GB) is higher on all-weather (AW) surfaces than on turf. However, to date no studies have focused on identifying risk factors for injury specific to AW racing. Therefore, the objective of the curre... Read More about Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013).

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.

Phenotypic heterogeneity of peripheral monocytes in healthy dogs (2017)
Journal Article
Gibbons, N., Goulart, M. R., Chang, Y. M., Efstathiou, K., Purcell, R., Wu, Y., …Garden, O. A. (2017). Phenotypic heterogeneity of peripheral monocytes in healthy dogs. Veterinary Immunology and Immunopathology, 190, 26-30. https://doi.org/10.1016/j.vetimm.2017.06.007

Monocytes are key cells of the innate immune system. Their phenotypic and functional roles have been investigated in humans, mice and other animals, such as the rat, pig and cow. To date, detailed phenotypic analysis of monocytes has not been underta... Read More about Phenotypic heterogeneity of peripheral monocytes in healthy dogs.

Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes (2017)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Volk, H. A., & Pelligand, L. (2017). Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes. Veterinary Anaesthesia and Analgesia, 44(3), 600-614. https://doi.org/10.1016/j.vaa.2016.09.004

Objective

To study feasibility and test-retest repeatability of a sensory threshold examination protocol (STEP) and report quantitative sensory threshold distributions in healthy dogs.

Study design

Prospective, observational, cohort study.... Read More about Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes.

Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers (2017)
Journal Article
Mahendran, S. A., Huxley, J. N., Chang, Y. M., Burnell, M., Barrett, D. C., Whay, H. R., …Bell, N. J. (2017). Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers. https://doi.org/10.1016/j.tvjl.2017.01.011

The objective of this study was to assess both independent and combined effects of routine foot trimming of heifers at 3 weeks pre-calving and 100 days post calving on the first lactation lameness and lactation productivity. A total of 419 pre-calvin... Read More about Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers.