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All Outputs (38)

Analysis of NOD1, NOD2, TLR1, TLR2, TLR4, TLR5, TLR6 and TLR9 genes in anal furunculosis of German shepherd dogs
Journal Article
House, A. K., Binns, M. M., Gregory, S. P., & Catchpole, B. Analysis of NOD1, NOD2, TLR1, TLR2, TLR4, TLR5, TLR6 and TLR9 genes in anal furunculosis of German shepherd dogs. Tissue Antigens, 73(3), 250-254. https://doi.org/10.1111/j.1399-0039.2008.01190.x

Anal furunculosis (AF) primarily affects German shepherd dogs (GSD) and is characterised by inflammation and ulceration of the perianal tissues with development of cutaneous sinuses or rectocutaneous fistulae. Investigation of pattern recognition rec... Read More about Analysis of NOD1, NOD2, TLR1, TLR2, TLR4, TLR5, TLR6 and TLR9 genes in anal furunculosis of German shepherd dogs.

Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
Journal Article
Dutton, L. C., Dudhia, J., Catchpole, B., Hodhkiss-Geere, H., Werling, D., & Connolly, D. J. (in press). Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor. https://doi.org/10.1038/s41598-018-31569-1

derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focusse... Read More about Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor.

Pattern-recognition receptor mRNA expression and function in canine monocyte/macrophages and relevance to canine anal furunuclosis
Journal Article
House, A. K., Gregory, S. P., & Catchpole, B. Pattern-recognition receptor mRNA expression and function in canine monocyte/macrophages and relevance to canine anal furunuclosis. Veterinary Immunology and Immunopathology, 124(3-4), 230-240. https://doi.org/10.1016/j.vetimm.2008.03.012

Pattern-recognition receptors (PRRs) are important components of the innate immune system, enabling early detection of infection. Defective PRR function has been implicated in several infectious and immune-mediated diseases of human beings. including... Read More about Pattern-recognition receptor mRNA expression and function in canine monocyte/macrophages and relevance to canine anal furunuclosis.

Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations
Journal Article
Davison, L. J., Walding, B. R., Herrtage, M. E., & Catchpole, B. Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations. Journal of Veterinary Internal Medicine, 22(6), 1317-1325. https://doi.org/10.1111/j.1939-1676.2008.0194.x

Background: Anti-insulin antibodies (AIA) occur in diabetic dogs after insulin therapy, although their clinical significance is unclear. Hypothesis: Treatment of diabetic dogs with heterologous insulin is more likely to stimulate production of AIA th... Read More about Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations.

Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy
Journal Article
Tivers, M. S., Catchpole, B., Gregory, S. P., & House, A. K. Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy. Veterinary Immunology and Immunopathology, 125(1/2), 31-36. https://doi.org/10.1016/j.vetimm.2008.04.018

German Shepherd Dogs have an increased incidence of anal furunculosis (AF), which is a disease characterized by inflammation and ulceration of the perianal tissues. Ciclosporin, an immunosuppressive drug, has been successfully used to treat AF, sugge... Read More about Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy.