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A multicenter randomized controlled trial of effect of medium-chain triglyceride dietary supplementation on epilepsy in dogs (2020)
Journal Article
Berk, B. A., Law, T. H., Packer, R. M. A., Wessmann, A., Bathen-Nöthen, A., Jokinen, T. S., Knebel, A., Tipold, A., Pelligand, L., Meads, Z., & Volk, H. A. (2020). A multicenter randomized controlled trial of effect of medium-chain triglyceride dietary supplementation on epilepsy in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15756

Dysautonomia in 53 cats and dogs: retrospective review of clinical data and outcome (2020)
Journal Article
Clarke, K. E., Sorrell, S., Breheny, C., Jepson, R. E., Adamantos, S., Milne, E. M., & Gunn-moore, D. (2020). Dysautonomia in 53 cats and dogs: retrospective review of clinical data and outcome. Veterinary Record, https://doi.org/10.1136/vr.105258

The aim of this study was to perform a retrospective multicentre review of clinical data relating to cats and dogs diagnosed with dysautonomia and to evaluate their outcome.

Use of nociceptive threshold testing in cats in experimental and clinical settings: a qualitative review (2020)
Journal Article
Adami, C., & Spadavecchia, C. (2020). Use of nociceptive threshold testing in cats in experimental and clinical settings: a qualitative review. Veterinary Anaesthesia and Analgesia, https://doi.org/10.1016/j.vaa.2019.12.009

The objective of this work was to review the scientific articles on the use of nociceptive threshold testing (NTT) in cats, and to summarise the clinical and experimental applications in this species.

Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study (2020)
Journal Article
Boswood, A., Gordon, S. G., Häggström, J., Vanselow, M., Wess, G., Stepien, R. L., Oyama, M. A., Keene, B. W., Bonagura, J., MacDonald, K. A., Patteson, M., Smith, S., Fox, P. R., Sanderson, K., Woolley, R., Szatmári, V., Menaut, P., Church, W. M., O'Sullivan, M. L., Jaudon, J.-P., …Watson, P. (2020). Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15753

The Evaluation of pimobendan in dogs with cardiomegaly caused by preclinical myxomatous mitral valve disease (EPIC) study monitored dogs with myxomatous mitral valve disease (MMVD) as they developed congestive heart failure (CHF).

Surgical management of a sinonasal angiomatous polyp and associated cyst involving the paranasal sinuses and nasal cavity via standing axial rhinotomy (2020)
Journal Article
Rowley, K. J., Fiske-Jackson, A. R., Williams, J. M., Jones, A. L., & Townsend, N. B. (2020). Surgical management of a sinonasal angiomatous polyp and associated cyst involving the paranasal sinuses and nasal cavity via standing axial rhinotomy. Equine Veterinary Education, https://doi.org/10.1111/eve.13261

This case report describes the successful surgical management of a sinonasal angiomatous polyp involving the dorsal conchal bullae, dorsal conchal sinus, ventral conchal sinus, ventral conchal bullae and ventral conchal recess of the left nasal cavit... Read More about Surgical management of a sinonasal angiomatous polyp and associated cyst involving the paranasal sinuses and nasal cavity via standing axial rhinotomy.

Development of a Cartilage Oligomeric Matrix Protein Neo-Epitope Assay for the Detection of Intra-Thecal Tendon Disease (2020)
Journal Article
Smith, R. K. W., Önnerfjord, P., Holmgren, K., di Grado, S., & Dudhia, J. (2020). Development of a Cartilage Oligomeric Matrix Protein Neo-Epitope Assay for the Detection of Intra-Thecal Tendon Disease. International Journal of Molecular Sciences, 21(6), 2155. https://doi.org/10.3390/ijms21062155

The diagnosis of tendon injury relies on clinical signs and diagnostic imaging but imaging is subjective and does not always correlate with clinical signs. A molecular marker would potentially offer a sensitive and specific diagnostic tool that could... Read More about Development of a Cartilage Oligomeric Matrix Protein Neo-Epitope Assay for the Detection of Intra-Thecal Tendon Disease.

Histopathological and immunohistochemical evaluation of cellular response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch for tendon repair (2020)
Journal Article
Rashid, M., Dudhia, J., Dakin, S. G., Snelling, S. J. B., De Godoy, R., Mouthuy, P.-A., Smith, R. K. W., Morrey, M., & Carr, A. J. (2020). Histopathological and immunohistochemical evaluation of cellular response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch for tendon repair. Scientific Reports, 10(1), https://doi.org/10.1038/s41598-020-61725-5

We investigated endogenous tissue response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch intended for tendon repair. A sheep tendon injury model characterised by a natural history of consistent failure of healing was... Read More about Histopathological and immunohistochemical evaluation of cellular response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch for tendon repair.

MicroCT optimisation for imaging fascicular anatomy in peripheral nerves (2020)
Journal Article
Thompson, N., Ravagli, E., Mastitskaya, S., Iacoviello, F., Aristovich, K., Perkins, J. D. M., Shearing, P. R., & Holder, D. (2020). MicroCT optimisation for imaging fascicular anatomy in peripheral nerves. Journal of Neuroscience Methods, 108652. https://doi.org/10.1016/j.jneumeth.2020.108652

Due to the lack of understanding of the fascicular organisation, vagus nerve stimulation (VNS) leads to unwanted off-target effects. Micro-computed tomography (microCT) can be used to trace fascicles from periphery and image fascicular anatomy.
In t... Read More about MicroCT optimisation for imaging fascicular anatomy in peripheral nerves.

Clinicopathological characteristics and prognostic factors for canine multicentric non‐indolent T‐cell lymphoma: 107 cases (2020)
Journal Article
Purzycka, K., Peters, L. M., Desmas, I., Davies, O., Chang, Y. M., & Lara‐Garcia, A. (2020). Clinicopathological characteristics and prognostic factors for canine multicentric non‐indolent T‐cell lymphoma: 107 cases. Veterinary and Comparative Oncology, https://doi.org/10.1111/vco.12589

Canine lymphoma, as the most common haematopoietic malignancy, encompasses a group of heterogeneous diseases and even within the T-cell immunophenotype, differences in clinical presentation and responses to treatment exist. The aim of this retrospect... Read More about Clinicopathological characteristics and prognostic factors for canine multicentric non‐indolent T‐cell lymphoma: 107 cases.

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation (2020)
Journal Article
Wu, Y., Chang, Y. M., Polton, G., Stell, A. J., Szladovits, B., Macfarlane, M., Peters, L. M., Priestnall, S. L., Bacon, N. J., Kow, K., Stewart, S., Sharma, E., Goulart, M. R., Gribben, J., Xia, D., & Garden, O. A. (2020). Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00307

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A... Read More about Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation.

Prospective evaluation of the utility of cross‐matching prior to first transfusion in cats: 101 cases (2020)
Journal Article
Humm, K. R., & Chan, D. L. (2020). Prospective evaluation of the utility of cross‐matching prior to first transfusion in cats: 101 cases. Journal of Small Animal Practice, 61(5), 285-291. https://doi.org/10.1111/jsap.13124

Objectives

To: (1) assess the frequency of crossmatch incompatibility in naïve feline blood transfusion recipients using two crossmatching methods, (2) measure the effect of crossmatch incompatibility on change in packed cell volume following tran... Read More about Prospective evaluation of the utility of cross‐matching prior to first transfusion in cats: 101 cases.

Quantitative lameness assessment in the horse based on upper body movement symmetry: The effect of different filtering techniques on the quantification of motion symmetry (2020)
Journal Article
Serra Bragança, F. M., Roepstorff, C., Rhodin, M., Pfau, T., Van Weeren, P. R., & Roepstorff, L. (2020). Quantitative lameness assessment in the horse based on upper body movement symmetry: The effect of different filtering techniques on the quantification of motion symmetry. Biomolecular NMR Assignments, 57, https://doi.org/10.1016/j.bspc.2019.101674

Quantitative gait analysis in horses is rapidly gaining importance, both clinically and in research. The number of available systems is increasing, but the methods of signal analysis differ between systems and research groups. Our objectives are to d... Read More about Quantitative lameness assessment in the horse based on upper body movement symmetry: The effect of different filtering techniques on the quantification of motion symmetry.

Malassezia Yeasts in Veterinary Dermatology: An Updated Overview (2020)
Journal Article
Guillot, J., & Bond, R. (2020). Malassezia Yeasts in Veterinary Dermatology: An Updated Overview. Frontiers in Cellular and Infection Microbiology, 10(79), https://doi.org/10.3389/fcimb.2020.00079

Lipophilic yeasts of the genus Malassezia are important skin commensals and opportunistic skin pathogens in a variety of animals. The species M. pachydermatis was first isolated from the skin of a captive Indian rhinoceros with an exfoliative dermati... Read More about Malassezia Yeasts in Veterinary Dermatology: An Updated Overview.

Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro (2020)
Journal Article
Kafarnik, C., McClellan, A., Dziasko, M., Daniels, J. T., & Guest, D. J. (2020). Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro. Stem Cells and Development, 29(7), https://doi.org/10.1089/scd.2019.0163

The objective of this study was to determine whether corneal stromal cells (CSCs) from the limbal and central corneal stroma in dogs have multipotent mesenchymal stem/stromal cell (MSC) properties, and whether this cell population can be differentiat... Read More about Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro.

Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure (2020)
Journal Article
Dargue, R., Zia, R., Lau, C., Nicholls, A. W., Dare, T. O., Lee, K. C. L., Jalan, R., Coen, M., & Wilson, I. D. (2020). Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure. Toxicological Sciences, https://doi.org/10.1093/toxsci/kfaa023

The metabolic fate, toxicity and effects on endogenous metabolism of paracetamol (acetaminophen, APAP) in 22 female Landrace cross large white pigs were evaluated in a model of acute liver failure (ALF). Anaesthetized pigs were initially dosed at 250... Read More about Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure.

Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK (2020)
Journal Article
O'Neill, D. G., Brodbelt, D. C., Hodge, R., Church, D. B., & Meeson, R. L. (2020). Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK. https://doi.org/10.1186/s40575-020-0080-5

Conditions affecting the elbow joint are a common cause of lameness in dogs. Primary-care veterinary clinical data are now recognised as a valuable research resource. Using data from the VetCompass Programme, this study aimed to report the frequency... Read More about Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK.