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MicroCT optimisation for imaging fascicular anatomy in peripheral nerves

Thompson, N; Ravagli, E; Mastitskaya, S; Iacoviello, F; Aristovich, K; Perkins, J D M; Shearing, P R; Holder, D


N Thompson

E Ravagli

S Mastitskaya

F Iacoviello

K Aristovich

J D M Perkins

P R Shearing

D Holder


Due to the lack of understanding of the fascicular organisation, vagus nerve stimulation (VNS) leads to unwanted off-target effects. Micro-computed tomography (microCT) can be used to trace fascicles from periphery and image fascicular anatomy.
In this study, we present a simple and reproducible method for imaging fascicles in peripheral nerves with iodine staining and microCT for the determination of fascicular anatomy and organisation.


Thompson, N., Ravagli, E., Mastitskaya, S., Iacoviello, F., Aristovich, K., Perkins, J. D. M., …Holder, D. (2020). MicroCT optimisation for imaging fascicular anatomy in peripheral nerves. Journal of Neuroscience Methods, 108652.

Journal Article Type Article
Acceptance Date Feb 25, 2020
Publication Date Mar 13, 2020
Deposit Date Mar 30, 2020
Publicly Available Date Nov 20, 2020
Journal Journal of Neuroscience Methods
Print ISSN 0165-0270
Publisher Elsevier
Peer Reviewed Peer Reviewed
Pages 108652
Public URL


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