All Outputs (165)

Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation (2018)
Journal Article
Martinez, M., Gehring, R., Mochel, J. P., Pade, D., & Pelligand, L. (2018). Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation. Journal of Veterinary Pharmacology and Therapeutics, 41(4), E-68. https://doi.org/10.1111/jvp.12666

During the 2017 Biennial meeting, the American Academy of Veterinary Pharmacology and Therapeutics hosted a 1‐day session on the influence of population variability on dose‐exposure‐response relationships. In Part I, we highlighted some of the source... Read More about Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation.

Outcome and prognostic factors in medically treated canine prostatic carcinomas: A multi-institutional study (2018)
Journal Article
Ravicini, S., Baines, S. J., Taylor, A., Amores-Fuster, I., Mason, S. L., & Treggiari, E. (2018). Outcome and prognostic factors in medically treated canine prostatic carcinomas: A multi-institutional study. Veterinary and Comparative Oncology, 16(4), 450-458. https://doi.org/10.1111/vco.12400

Literature describing medical treatment of canine prostatic carcinoma (PC) is sparse. The aims of this study were to assess outcomes, including time to progression (TTP) and median survival time (MST), of canine PC treated with non‐steroidal anti‐inf... Read More about Outcome and prognostic factors in medically treated canine prostatic carcinomas: A multi-institutional study.

Somatosensory and motor evoked potentials in dogs with chronic severe thoracolumbar spinal cord injury (2018)
Journal Article
Zu, H. Z., Jeffery, N. D., & Granger, N. (2018). Somatosensory and motor evoked potentials in dogs with chronic severe thoracolumbar spinal cord injury. https://doi.org/10.1016/j.tvjl.2018.05.007

ome dogs that become paraplegic after severe spinal cord injury regain ambulation on the pelvic limbs despite permanent loss of pelvic limb sensation, a phenomenon termed ‘spinal walking’. Plastic changes in spinal cord circuitry are thought to media... Read More about Somatosensory and motor evoked potentials in dogs with chronic severe thoracolumbar spinal cord injury.

Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments (2018)
Journal Article
O'Brien, E. J. O., & Smith, R. K. W. (2018). Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments. https://doi.org/10.1111/vru.12628

Tendon/ligament mineralization is recognized in horses but information regarding its clinical significance is limited. The aims of this observational study were to report the structures most commonly affected by ultrasonographically detectable minera... Read More about Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments.

Validity and application of immunoturbidimetric and enzyme-linked immunosorbent assays for the measurement of adiponectin concentration in ponies (2018)
Journal Article
Menzies-Gow, N. J., Knowles, E. J., Rogers, I., & Rendle, D. I. (2018). Validity and application of immunoturbidimetric and enzyme-linked immunosorbent assays for the measurement of adiponectin concentration in ponies. Equine Veterinary Journal, 51(1), 33-37. https://doi.org/10.1111/evj.12960

Autologous Stem Cells in Achilles Tendinopathy (ASCAT): protocol for a phase IIA, single-centre, proof-of-concept study (2018)
Journal Article
Goldberg, A. J., Zaidi, R., Brooking, D., Kim, L., Korda, M., Masci, L., …Smith, R. K. W. (2018). Autologous Stem Cells in Achilles Tendinopathy (ASCAT): protocol for a phase IIA, single-centre, proof-of-concept study. BMJ Open, 8(5), https://doi.org/10.1136/bmjopen-2018-021600

C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints? (2018)
Journal Article
Brocal, J., De Decker, S., José-López, R., Manzanilla, E. G., Penderis, J., Stalin, C., …Gutierrez-Quintana, R. (2018). C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints?. Journal of Anatomy, https://doi.org/10.1111/joa.12822

The number of cervical vertebrae in mammals is almost constant at seven, regardless of their neck length, implying that there is selection against variation in this number. Homebox (Hox) genes are involved in this evolutionary mammalian conservation,... Read More about C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints?.

Does ‘hacking’ surface type affect equine forelimb foot placement, movement symmetry or hoof impact deceleration during ridden walk and trot exercise (2018)
Journal Article
Barstow, A., Bailey, J., Campbell, J., Harris, C., Weller, R., & Pfau, T. (2018). Does ‘hacking’ surface type affect equine forelimb foot placement, movement symmetry or hoof impact deceleration during ridden walk and trot exercise. Equine Veterinary Journal, https://doi.org/10.1111/evj.12952

Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy (2018)
Journal Article
Spalla, I., Payne, J. R., Borgeat, K. A., Fuentes, V. L., & Connolly, D. J. (2018). Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy. Journal of Veterinary Cardiology, 20(3), 154-164. https://doi.org/10.1016/j.jvc.2018.04.005

Hypertrophic cardiomyopathy (HCM) has a variable prognosis; left atrial size, presence of clinical signs and left ventricular systolic function have been shown to predict outcomes. Mitral annular plane systolic excursion (MAPSE) and tricuspid annular... Read More about Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy.

Use of ultrasonography to confirm epidural catheter position in a cat (2018)
Journal Article
Machin, H., Merlin, T., & Viscasillas, J. (2018). Use of ultrasonography to confirm epidural catheter position in a cat. Veterinary Anaesthesia and Analgesia, https://doi.org/10.1016/j.vaa.2018.03.012

Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures (2018)
Journal Article
Osagie-Clouard, L., Kaufmann, J., Blunn, G., Coathup, M., Pendegrass, C., Meeson, R. L., …Moazen, M. (2018). Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures. Journal of Orthopaedic Research, https://doi.org/10.1002/jor.24034

The use of external fixators allows for the direct investigation of newly formed interfragmentary bone, and the radiographic evaluation of the fracture. We validated the results of a finite element model with the in vitro stiffness' of two widely use... Read More about Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures.

Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013 (2018)
Journal Article
O'Neill, D. G., Baral, L., Church, D. B., Brodbelt, D. C., & Packer, R. M. A. (2018). Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013. Canine Genetics and Epidemiology, 5(3), https://doi.org/10.1186/s40575-018-0057-9

Approach to canine paroxysmal dyskinesias (2018)
Journal Article
Posporis, C., Wyatt, S., & Wessmann, A. (2018). Approach to canine paroxysmal dyskinesias. Companion Animal, 23(5), https://doi.org/10.12968/coan.2018.23.5.276

The term ‘paroxysmal dyskinesia’ (PD) describes a manifestation of involuntary movement or muscle tone, which by definition is episodic in nature and self-limiting. The PDs remain poorly understood and frequently under-recognised conditions in vete... Read More about Approach to canine paroxysmal dyskinesias.

Postoperative survival and early complications after intracranial surgery in dogs (2018)
Journal Article
Forward, A. K., Volk, H. A., & De Decker, S. (2018). Postoperative survival and early complications after intracranial surgery in dogs. Vector-Borne and Zoonotic Diseases, 47(4), 549-554. https://doi.org/10.1111/vsu.12785

Objective To describe survival and early postoperative outcome after intracranial surgery in dogs. Study design Retrospective case series. Animals Fifty client-owned dogs that underwent intracranial surgery. Methods Records were searched... Read More about Postoperative survival and early complications after intracranial surgery in dogs.

Quantification of the effect of instrumentation error in objective gait assessment in the horse on hindlimb symmetry parameters (2018)
Journal Article
Serra Bragança, F., Rhodin, M., Wiestner, T., Hernlund, E., Pfau, T., Van Weeren, P. R., & Weishaupt, M. A. (2018). Quantification of the effect of instrumentation error in objective gait assessment in the horse on hindlimb symmetry parameters. Equine Veterinary Journal, 50(3), 370-376. https://doi.org/10.1111/evj.12766

Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease (2018)
Journal Article
Van Den Broek, D. H. N., Chang, Y. M., Elliott, J., & Jepson, R. E. (2018). Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease. Journal of Veterinary Internal Medicine, 32(4), 1359-1371. https://doi.org/10.1111/jvim.15141

Preliminary assessment of cognitive impairments in canine idiopathic epilepsy (2018)
Journal Article
Winter, J., Packer, R. M. A., & Volk, H. A. (2018). Preliminary assessment of cognitive impairments in canine idiopathic epilepsy. Veterinary Record, https://doi.org/10.1136/vr.104603

In humans, epilepsy can induce or accelerate cognitive impairment (CI). There is emerging evidence of CI in dogs with idiopathic epilepsy (IE) from recent epidemiological studies. The aim of our study was to assess CI in dogs with IE using two tests... Read More about Preliminary assessment of cognitive impairments in canine idiopathic epilepsy.

A study of the pharmacokinetics and thromboxane inhibitory activity of a single intramuscular dose of carprofen as a means to establish its potential use as an analgesic drug in white rhinoceros (2018)
Journal Article
Leiberich, M., Krebber, R., Hewetson, M., Marais, J., & Naidoo, V. (2018). A study of the pharmacokinetics and thromboxane inhibitory activity of a single intramuscular dose of carprofen as a means to establish its potential use as an analgesic drug in white rhinoceros. Journal of Veterinary Pharmacology and Therapeutics, 41(4), 605-613. https://doi.org/10.1111/jvp.12508

The alleviation of pain and prevention of suffering are key aspects of animal welfare. Unfortunately, analgesic drugs are not available for all species. White rhinoceros (Ceratotherium simum), representing one of such species, which survive poaching... Read More about A study of the pharmacokinetics and thromboxane inhibitory activity of a single intramuscular dose of carprofen as a means to establish its potential use as an analgesic drug in white rhinoceros.

Pathological classification of equine recurrent laryngeal neuropathy (2018)
Journal Article
Draper, A. C. E., & Piercy, R. J. (2018). Pathological classification of equine recurrent laryngeal neuropathy. Journal of Veterinary Internal Medicine, 32(4), 1397-1409. https://doi.org/10.1111/jvim.15142

Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left‐sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle p... Read More about Pathological classification of equine recurrent laryngeal neuropathy.

International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study (2018)
Journal Article
Fox, P. R., Keene, B. W., Lamb, K., Schober, K. A., Chetboul, V., Fuentes, V. L., …Ohara, V. Y. T. (2018). International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study. Journal of Veterinary Internal Medicine, 32(3), 930-943. https://doi.org/10.1111/jvim.15122