Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid
Journal Article
Graham, V. S., Lawson, C., Wheeler-Jones, C. P. D., Perona, J. S., Ruiz-Gutierrez, V., & Botham, K. M. Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid. European Journal of Nutrition, 51(3), 301-309. https://doi.org/10.1007/s00394-011-0215-2
All Outputs (85)
C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells
Journal Article
Rautureau, Y., Gowers, I., Wheeler-Jones, C. P. D., & Baxter, G. F. C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells. https://doi.org/10.1111/j.1474-8673.2009.00449.x
Targeting hyaluronan of the endothelial glycocalyx for therapeutic intervention
Journal Article
Wheeler-Jones, C. P. D., Farrar, C. E., & Pitsillides, A. A. Targeting hyaluronan of the endothelial glycocalyx for therapeutic intervention
Endotoxin-induced activation of equine digital vein endothelial cells: Role of p38 MAPK
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Cunningham, F. M., & Elliott, J. Endotoxin-induced activation of equine digital vein endothelial cells: Role of p38 MAPK. Veterinary Immunology and Immunopathology, 129(3-4), 174-180. https://doi.org/10.1016/j.vetimm.2008.11.008
Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Elliott, J., & Cunningham, F. M. Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases. Journal of Veterinary Pharmacology and Therapeutics, 32(2), 189-196. https://doi.org/10.1111/j.1365-2885.2008.01020.xLipopolysaccharide (LPS) can activate equine platelets directly or indirectly, via leukocyte-derived platelet activating factor (PAF). Thromboxane (Tx) production by LPS-stimulated equine platelets requires p38 MAPK and this kinase has been suggested... Read More about Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases.
Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles
Journal Article
De Pascale, C., Graham, V., Fowkes, R. C., Wheeler-Jones, C. P. D., & Botham, K. M. Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles. FEBS Journal, 276(19), 5689-5702. https://doi.org/10.1111/j.1742-4658.2009.07260.x
Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow
Journal Article
Macey, M. G., Wolf, S. I., Wheeler-Jones, C. P. D., & Lawson, C. Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow. Journal of Immunological Methods, 350(1-2), 133-141. https://doi.org/10.1016/j.jim.2009.08.007
Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells
Journal Article
Thompson, I. R., Chand, A. N., Jonas, K. C., Burrin, J. M., Steinhelper, M. E., Wheeler-Jones, C. P. D., McArdle, C. A., & Fowkes, R. C. Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells. Journal of Endocrinology, 203(2), 215-229. https://doi.org/10.1677/joe-09-0189
Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells
Journal Article
Wheeler-Jones, C. P. D., Farrar, C. E., & Garonna, E. Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells. Biochemical Society Transactions, 37, 1179-1183. https://doi.org/10.1042/bst0371179
Mechanical strain and estrogen activate estrogen receptor alpha in bone cells
Journal Article
Jessop, H. L., Sjoberg, M., Cheng, M. Z., Zaman, G., Wheeler-Jones, C. P. D., & Lanyon, L. E. Mechanical strain and estrogen activate estrogen receptor alpha in bone cells. Journal of Bone and Mineral Research, 16(6), 1045-1055. https://doi.org/10.1359/jbmr.2001.16.6.1045
Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium
Journal Article
Houliston, R. A., Pearson, J. D., & Wheeler-Jones, C. P. D. Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium
sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells
Journal Article
Houliston, R. A., & Wheeler-Jones, C. P. D. sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells. Biochemical and Biophysical Research Communications, 287(4), 881-887. https://doi.org/10.1006/bbrc.2001.5681
A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion
Journal Article
Persaud, S. J., Roderigo-Milne, H. M., Squires, P. E., Sugden, D., Wheeler-Jones, C. P. D., Marsh, P. J., Belin, V. D., Luther, M. J., & Jones, P. M. A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion. Diabetes, 51(1), 98-104
Early activation of the p42/p44(MAPK) pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism
Journal Article
Wyatt, A. W., Steinert, J. R., Wheeler-Jones, C. P. D., Morgan, A. J., Sugden, D., Pearson, J. D., Sobrevia, L., & Mann, G. E. Early activation of the p42/p44(MAPK) pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism. FASEB Journal, 16(12), 1584-1594. https://doi.org/10.1096/fj.01-0125com
Differential exocytosis from human endothelial cells evoked by high intracellular Ca2+ concentration
Journal Article
Zupancic, G., Ogden, D., Magnus, C. J., Wheeler-Jones, C. P. D., & Carter, T. D. Differential exocytosis from human endothelial cells evoked by high intracellular Ca2+ concentration. Journal of Physiology, 544(3), 741-755. https://doi.org/10.1113/jphysiol.2002.027490
Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production
Journal Article
Hodges, R. J., Jenkins, R. G., Wheeler-Jones, C. P. D., Copeman, D. M., Bottoms, S. E., Bellingan, G. J., Nanthakumar, C. B., Laurent, G. J., Hart, S. L., Foster, M. L., & McAnulty, R. J. Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production. American Journal of Pathology, 165(5), 1663-1676. https://doi.org/10.1016/S0002-9440%2810%2963423-2
Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific
Journal Article
Dewi, D. A., Abayasekara, D. R. E., & Wheeler-Jones, C. P. D. Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific. Endocrinology, 143(3), 877-888. https://doi.org/10.1210/en.143.3.877
Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells
Journal Article
Houliston, R. A., Keogh, R. J., Sugden, D., Dudhia, J., Carter, T. D., & Wheeler-Jones, C. P. D. Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells. Thrombosis and Haemostasis, 88(2), 321-28
Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas
Journal Article
Keogh, R. J., Houliston, R. A., & Wheeler-Jones, C. P. D. Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas. Biochemical and Biophysical Research Communications, 290(5), 1470-1477. https://doi.org/10.1006/bbrc.2002.6350
Thrombin-stimnlated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases
Journal Article
Keogh, R. J., Houliston, R. A., & Wheeler-Jones, C. P. D. Thrombin-stimnlated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases. Biochemical and Biophysical Research Communications, 294(5), 1001-1008. https://doi.org/10.1016/S0006-291X%2802%2900568-5