All Outputs (153)

The importance of fine-scale predictors of wild boar presence in an isolated population (2022)
Journal Article
Bacigalupo, S. A., Chang, Y.-M., Dixon, L. K., Gubbins, S., Kucharski, A. J., & Drewe, J. A. (2022). The importance of fine-scale predictors of wild boar presence in an isolated population. Methods in Ecology and Evolution, https://doi.org/10.1002/ece3.9031

1. Predicting the likelihood of wildlife presence at potential wildlife-livestock interfaces is challenging. These interfaces are usually relatively small geographical areas where landscapes show large variation over small distances. Models of wildli... Read More about The importance of fine-scale predictors of wild boar presence in an isolated population.

The importance of fine-scale predictors of wild boar habitat use in an isolated population (2022)
Journal Article
Bacigalupo, S. A., Chang, Y.-M., Dixon, L. K., Gubbins, S., & Drewe, J. A. (2022). The importance of fine-scale predictors of wild boar habitat use in an isolated population. Ecology and Evolution, 12, -. https://doi.org/10.1002/ece3.9031

1. Predicting the likelihood of wildlife presence at potential wildlife-livestock interfaces is challenging. These interfaces are usually relatively small geographical areas where landscapes show large variation over small distances. Models of wildli... Read More about The importance of fine-scale predictors of wild boar habitat use in an isolated population.

Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass (2022)
Journal Article
Starybrat, D., Jepson, R., Bristow, P., Peterson, S., Yerramilli, M., Yerramilli, M., Chang, Y.-M., & Cortellini, S. (online). Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass. Journal of Veterinary Emergency and Critical Care,

Objective - Assess the occurrence of acute kidney injury (AKI) in dogs undergoing cardiac surgery under cardiopulmonary bypass (CPB) and explore associations between traditional and novel serum and urinary biomarkers.
Design – Prospective cohort st... Read More about Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.

Machine learning classification methods informing the management of inconclusive reactors at bovine tuberculosis surveillance tests in England (2021)
Journal Article
Romero, M. P., Chang, Y.-M., Brunton, L. A., Parry, J., Prosser, A., Upton, P., & Drewe, J. A. (2021). Machine learning classification methods informing the management of inconclusive reactors at bovine tuberculosis surveillance tests in England. Preventive Veterinary Medicine,

Bovine tuberculosis (bTB) remains one of the most complex, challenging, and costly animal health problems in England. Identifying and promptly removing all infected cattle from affected herds is key to its eradication strategy; the imperfect sensitiv... Read More about Machine learning classification methods informing the management of inconclusive reactors at bovine tuberculosis surveillance tests in England.

Predictors of laminitis development in a cohort of non-laminitic ponies (2021)
Journal Article
Knowles, E., Elliott, J., Harris, P., Chang, R., & Menzies-Gow, N. (2021). Predictors of laminitis development in a cohort of non-laminitic ponies. Equine Veterinary Journal, https://doi.org/10.1111/evj.31_13492

Background: Quantifying the risk of laminitis development requires improvement.
Objectives: To identify the most useful physical examination, metabolic and management factors to predict future laminitis development in client-owned, non-laminitic pon... Read More about Predictors of laminitis development in a cohort of non-laminitic ponies.

Bite Wound Management In Ring-Tailed Lemurs: A Retrospective Study Of Bite Wound Management In Ring-Tailed Lemurs (Lemur Catta) Housed Within Five British Zoos. (2021)
Journal Article
Ceccolini, M., Hedley, J., Chang, Y.-M., & Guthrie, A. (in press). Bite Wound Management In Ring-Tailed Lemurs: A Retrospective Study Of Bite Wound Management In Ring-Tailed Lemurs (Lemur Catta) Housed Within Five British Zoos. Journal of Zoo and Wildlife Medicine,

Captive nonhuman primates frequently experience bite wounds inflicted by conspecifics; however, few studies evaluate wound management in these animals. This study evaluates bite wound management in 35 captive ring-tailed lemurs (RTL, Lemur catta) hel... Read More about Bite Wound Management In Ring-Tailed Lemurs: A Retrospective Study Of Bite Wound Management In Ring-Tailed Lemurs (Lemur Catta) Housed Within Five British Zoos..

Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken (2021)
Journal Article
Abeyesinghe, S., Abeyesinghe, S., Chancellor, N., Hernandez Moore, D., Chang, Y.-M., Pearce, J., Demmers, T., & Nicol, C. (2021). Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken. animal, 15(7), Article 100261. https://doi.org/10.1016/j.animal.2021.100261

Broiler chickens are prone to a range of complex health and welfare issues. To support informed selection of welfare traits whilst minimising impact on production efficiency and to address a major gap in understanding, we systematically explored asso... Read More about Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken.

Changes in retinal vascular diameters in senior and geriatric cats in association with variation in systemic blood pressure (2021)
Journal Article
Enache, A., Dietrich, U., Drury, O., Trucco, E., MacGillivray, T., Syme, H., Elliott, J., & Chang, Y.-M. (2021). Changes in retinal vascular diameters in senior and geriatric cats in association with variation in systemic blood pressure. Journal of Feline Medicine and Surgery,

Objectives Early diagnosis of arterial hypertension is essential to prevent target organ damage. In humans, retinal arteriolar narrowing predicts hypertension. This blinded prospective observational study investigated the retinal vessel diameters amo... Read More about Changes in retinal vascular diameters in senior and geriatric cats in association with variation in systemic blood pressure.

Systematic analysis reveals that colony housing aligns gait profiles and strengthens link between 1 histological and micro-CT bone markers in rat models of osteoarthritis 2 Short running title: Colony housing strengthens osteoarthritis research (2021)
Journal Article
Chang, Y.-M., Menges, S., Westhof, A., Kleinschmidt-Doerr, K., Brenneis, C., Pitsillides, A. A., & Chang, Y.-M. (in press). Systematic analysis reveals that colony housing aligns gait profiles and strengthens link between 1 histological and micro-CT bone markers in rat models of osteoarthritis 2 Short running title: Colony housing strengthens osteoarthritis research. FASEB Journal, -. https://doi.org/10.1096/fj.202002009R

A comparison of the value of two machine learning predictive models to support bovine tuberculosis disease control in England (2021)
Journal Article
Romero, M. P., Pilar Romero, M., Chang, Y.-M., Brunton, L. A., Prosser, A., Upton, P., Rees, E., Tearne, O., Arnold, M., Stevens, K., & Drewe, J. A. (2021). A comparison of the value of two machine learning predictive models to support bovine tuberculosis disease control in England. Preventive Veterinary Medicine,

Nearly a decade into Defra’s current eradication strategy (Defra, 2014, 2011), bovine tuberculosis (bTB) remains a serious animal health problem in England, with c.30,000 cattle slaughtered annually in the fight against this insidious disease. There... Read More about A comparison of the value of two machine learning predictive models to support bovine tuberculosis disease control in England.

Risk factors associated with disturbances of calcium homeostasis after initiation of a phosphate-restricted diet in cats with chronic kidney disease (2020)
Journal Article
Jepson, R., Elliott, J., Geddes, R., Chang, Y.-M., & Tang, P. (2020). Risk factors associated with disturbances of calcium homeostasis after initiation of a phosphate-restricted diet in cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 1-12. https://doi.org/10.1111/jvim.15996

Background

Dietary phosphate restriction improves survival in cats with chronic kidney disease (CKD). However, feeding a phosphate‐restricted diet may disrupt calcium homeostasis leading to hypercalcemia in some cats.

Objectives

To identify... Read More about Risk factors associated with disturbances of calcium homeostasis after initiation of a phosphate-restricted diet in cats with chronic kidney disease.

The Effect of Visitors on the Behavior of Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla) (2020)
Journal Article
Lewis, R. N., Chang, Y. M., Ferguson, A., Lee, T., Clifforde, L., & Abeyesinghe, S. M. (2020). The Effect of Visitors on the Behavior of Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla). Zoo Biology, https://doi.org/10.1002/zoo.21552

Primates, especially apes, are popular with the public, often attracting large crowds. These crowds could cause behavioral change in captive primates, whether positive, neutral, or negative. We examined the impact of visitors on the behavior of six w... Read More about The Effect of Visitors on the Behavior of Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla).

Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’ (2020)
Journal Article
Buzdugan, S. N., Chang, Y. M., Huntington, B., Rushton, J., Guitian, J., Alarcon, P., & Blake, D. P. (2020). Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’. Preventive Veterinary Medicine, 105036. https://doi.org/10.1016/j.prevetmed.2020.105036

Slaughterhouse condemnation of broiler chickens results from identification of polymorphic pathological conditions during meat inspection from arrival and on theslaughter line. While conditions that result in condemnation are multifactorial, identifi... Read More about Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’.

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation (2020)
Journal Article
Wu, Y., Chang, Y. M., Polton, G., Stell, A. J., Szladovits, B., Macfarlane, M., Peters, L. M., Priestnall, S. L., Bacon, N. J., Kow, K., Stewart, S., Sharma, E., Goulart, M. R., Gribben, J., Xia, D., & Garden, O. A. (2020). Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00307

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A... Read More about Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation.

Lasting organ-level bone mechanoadaptation is unrelated to local strain (2020)
Journal Article
Javaheri, B., Razi, H., Gohin, S., Wylie, S., Chang, Y. M., Salmon, P., Lee, P. D., & Pitsillides, A. A. (2020). Lasting organ-level bone mechanoadaptation is unrelated to local strain. Science Advances, 6(10), https://doi.org/10.1126/sciadv.aax8301

Bones adapt to mechanical forces according to strict principles predicting straight shape. Most bones are, however, paradoxically curved. To solve this paradox, we used computed tomography–based, four-dimensional imaging methods and computational ana... Read More about Lasting organ-level bone mechanoadaptation is unrelated to local strain.

Pre-analytical factors affecting whole blood and plasma glucose concentrations in loggerhead sea turtles (Caretta caretta) (2020)
Journal Article
Kunze, P. E., Perrault, J. R., Chang, Y. M., Manire, C. A., Clark, S., & Stacy, N. I. (2020). Pre-analytical factors affecting whole blood and plasma glucose concentrations in loggerhead sea turtles (Caretta caretta). PLoS ONE, 15, https://doi.org/10.1371/journal.pone.0229800

Blood glucose is vital for many physiological pathways and can be quantified by clinical chemistry analyzers and in-house point-of-care (POC) devices. Pre-analytical and analytical factors can influence blood glucose measurements. This project aimed... Read More about Pre-analytical factors affecting whole blood and plasma glucose concentrations in loggerhead sea turtles (Caretta caretta).

Impacts of UVB provision on serum vitamin D3, pigmentation, growth rates and total body mineral content in Mallorcan midwife toad larvae (Alytes muletensis) (2020)
Journal Article
Whatley, C., Tapley, B., Chang, Y. M., Newton-Yowens, J., McKendry, D., & Michaels, C. (2020). Impacts of UVB provision on serum vitamin D3, pigmentation, growth rates and total body mineral content in Mallorcan midwife toad larvae (Alytes muletensis). https://doi.org/10.19227/jzar.v8i1.434

The health of amphibians in captive breeding programmes can be compromised by nutritional metabolic bone disease and secondary hyperparathyroidism, which is a result of poor calcium metabolism or an inverse calcium:phosphorus ratio in the blood. UVB... Read More about Impacts of UVB provision on serum vitamin D3, pigmentation, growth rates and total body mineral content in Mallorcan midwife toad larvae (Alytes muletensis).

Osteoarthritis-related nociceptive behaviour following mechanical joint loading correlates with cartilage damage (2020)
Journal Article
Ter Heegde, F., Luiz, A. P., Santana-Varela, S., Magnusdottir, R., Hopkinson, M., Chang, Y. M., Poulet, B., Fowkes, R. C., Wood, J. N., & Chenu, C. (2020). Osteoarthritis-related nociceptive behaviour following mechanical joint loading correlates with cartilage damage. Osteoarthritis and Cartilage, 28(3), 383-395. https://doi.org/10.1016/j.joca.2019.12.004

In osteoarthritis (OA), the pain-structure relationship remains complex and poorly understood. Here, we used the mechanical joint loading (MJL) model of OA to investigate both knee pathology and nociceptive behaviour.

Association between hyponatremia and neurological dysfunction in hospitalized foals (2019)
Journal Article
Dunkel, B., Dodson, F., Chang, Y. M., & Slovis, N. M. (2019). Association between hyponatremia and neurological dysfunction in hospitalized foals. Journal of Veterinary Emergency and Critical Care, 30(1), 66-73. https://doi.org/10.1111/vec.12906

Hyponatremia and rapid correction of hyponatremia can lead to neurological abnormalities. The objective of the study was to determine whether plasma sodium concentrations (Na+) and speed of correction of hyponatremia are significantly associated with... Read More about Association between hyponatremia and neurological dysfunction in hospitalized foals.

Divergent evolution of terrestrial locomotor abilities in extant Crocodylia (2019)
Journal Article
Hutchinson, J. R., Felkler, D., Houston, K., Chang, Y. M., Brueggen, J., Kledzik, D., & Vliet, K. A. (2019). Divergent evolution of terrestrial locomotor abilities in extant Crocodylia. https://doi.org/10.1038/s41598-019-55768-6

Extant Crocodylia are exceptional because they employ almost the full range of quadrupedal footfall patterns (“gaits”) used by mammals; including asymmetrical gaits such as galloping and bounding. Perhaps this capacity evolved in stem Crocodylomorpha... Read More about Divergent evolution of terrestrial locomotor abilities in extant Crocodylia.