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All Outputs (119)

Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model (2025)
Journal Article
Binks, S., Crawford, A., Ives, E., Davison, L., Fox, H., Fower, A., Kaczmarska, A., Woodhall, M., Waters, P., Handel, A., Irani, S., Quintana, R. G., Chowdhury, F., Eriksson, S., & Pakozdy, A. (2025). Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model. Brain, Behavior, and Immunity, https://doi.org/10.1016/j.bbi.2025.02.018

Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs (2025)
Journal Article
O'Neill, D., Becker, S. D., Frosini, S.-M., Stapleton, L. E., Hughes, D. M., & Brodbelt, D. C. (2025). Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs. PLoS ONE, 20(2), e0318734. https://doi.org/10.1371/journal.pone.0318734

Standard bodyweights are an essential component of calculations that summarise many
population-level measures in companion animals, including the defined daily doses for
veterinary species (DDDVet) reporting antimicrobial usage. Standard species bo... Read More about Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs.

Evaluation of a nanoparticle influenza vaccine in the pig model (2025)
Journal Article
van Diemen, P., Lean, F., Ramsay, A., Mollett, B., Byrne, A., Núñez, A., Herbert, E., Moin, S., Crank, M., Graham, B., Kanekiyo, M., & Everett, H. (2025). Evaluation of a nanoparticle influenza vaccine in the pig model. Vaccine, 49, https://doi.org/10.1016/j.vaccine.2025.126844

Influenza A virus (IAV) infection causes substantial disease burden and vaccines capable of conferring broad immunity are lacking, necessitating frequent reformulation of seasonal vaccines. The purpose of this study was to evaluate the immunogenicity... Read More about Evaluation of a nanoparticle influenza vaccine in the pig model.

Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood (2025)
Journal Article
Merritt, B. L., O’Neill, D. G., Brand, C. L., Belshaw, Z., Dale, F. C., Pegram, C. L., & Packer, R. M. A. (in press). Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood. PLoS ONE, 20(2), e0316166. https://doi.org/10.1371/journal.pone.0316166

The owner-dog relationship is a critical component of sustained dog ownership. Increased understanding of risk factors for weak owner-dog relationships can identify owner-dog dyads at higher risk of poor welfare outcomes, including dog relinquishment... Read More about Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood.

Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis (2025)
Journal Article
Wallace, M., Falcone, S., Castillo, D., Williams, T., & Davison, L. (2025). Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis. Gene, 149314. https://doi.org/10.1016/j.gene.2025.149314

Abstract
Stomatocytosis is a rare spectrum of red blood cell (RBC) disorders. In humans, stomatocytosis is typically caused by genetic changes in specific ion exchange and transport genes. Stomatocytosis has been identified in dogs, however the unde... Read More about Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis.

Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax (2025)
Journal Article
Jones, C., Klever, J., Cordella, A., Fouriez-Lablee, V., Watton, T., & Llabres-Diaz, F. (2025). Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax. Veterinary Radiology and Ultrasound, 66(2), https://doi.org/10.1111/vru.70011

Aberrant right subclavian arteries (ARSAs) are a form of vascular ring anomaly (VRA) in dogs and the most common VRA in people. To date, there has been no large-scale study on ARSA in dogs and their potential clinical significance. For part one, a si... Read More about Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax.

Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics (2025)
Journal Article
Hopkinson, M., & Pitsillides, A. (2025). Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics. International Journal of Experimental Pathology, 106(2), https://doi.org/10.1111/iep.12525

Contributions made by the dystrophin-associated glycoprotein complex (DGC) to cell-cell and cell-extracellular matrix (ECM) interactions are vital in development, homeostasis and pathobiology. This review explores how DGC functions may extend to skel... Read More about Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics.

Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon (2025)
Journal Article
Beaumont, R. E., Smith, E. J., David, C., Paterson, Y. Z., Faull, E., & Guest, D. J. (2025). Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon. Cells & Development, https://doi.org/10.1016/j.cdev.2025.204003

Tendon injuries are a common problem in humans and horses. There is a high re-injury rate in both species due to the poor regeneration of adult tendon and the resulting formation of scar tissue. In contrast, fetal tendon injuries undergo scarless reg... Read More about Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon.

Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi (2025)
Journal Article
Larrosa-Godall, M., Ang, J., Leftwich, P., Gonzalez, E., Shackleford, L., Nevard, K., Noad, R., Anderson, M., & Alphey, L. (2025). Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi. Parasites and Vectors, 18(1), https://doi.org/10.1186/s13071-025-06688-0

BackgroundAnopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are... Read More about Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi.

Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens (2025)
Journal Article
Mead, A., Hughes, A., Azzariti, S., Toutain, P.-L., & Pelligand, L. (2025). Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13500

This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae, and Pasteurella multocida. In vitro time-kill assays and... Read More about Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens.

Climate change and campylobacteriosis from chicken meat: the changing risk factors and their importance (2025)
Journal Article
Queenan, K., & Haesler, B. (in press). Climate change and campylobacteriosis from chicken meat: the changing risk factors and their importance. Food Control, https://doi.org/10.1016/j.foodcont.2025.111193

Global consumption of chicken meat is currently the highest consumed meat per capita, and it continues to rise. Campylobacteriosis is one of the most reported gastrointestinal conditions, typically associated with chicken meat consumption. Cases are... Read More about Climate change and campylobacteriosis from chicken meat: the changing risk factors and their importance.

Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting (2025)
Journal Article
Figuereo, S., Mohamed, S., Takele, D., Sheikh, A., Abera, S., Mohamed, A., Lubogo, M., Abukar, H., Karanja, M., Bangura, S., Fayad, A., Adam, A., Osman, A., & Malik, S. (2025). Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting. Journal of epidemiology and global health, 15(1), https://doi.org/10.1007/s44197-025-00350-9

IntroductionEven before the COVID-19 pandemic, Somalia's national laboratory services had insufficient diagnostic capacities. We describe how the country moved rapidly from no testing capability to molecular testing and genomic sequencing for severe... Read More about Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting.

Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022) (2025)
Journal Article
Gaudio, E., Lipscomb, V. J., Cantatore, M., Blacklock, K., Gosling, M., Jack, M., Charlesworth, T., & Shales, C. J. (2025). Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022). Journal of Small Animal Practice, n/a(n/a), https://doi.org/10.1111/jsap.13830

Objectives To report clinical presentation, short-term outcome and complications of tracheal resection and anastomosis in dogs and cats. Materials and Methods Clinical records of pets treated with tracheal resection and anastomosis in seven UK-based... Read More about Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022).

Engaging communities in health promotion through community-based primary care and participatory research during the COVID-19 pandemic in Bolivia (2025)
Journal Article
Leyns, C., Ascarrunz, C., Rasguido, S., Rodriguez, P., Eid, D., & Guitian, J. (2025). Engaging communities in health promotion through community-based primary care and participatory research during the COVID-19 pandemic in Bolivia. Archives of Medical Research, 56(3), https://doi.org/10.1016/j.arcmed.2024.103154

Background. Most people in low- and middle-income countries work in the informal sector and lack social protection. In Bolivia, the unified family, community, and intercultural health model established universal health coverage for informal workers a... Read More about Engaging communities in health promotion through community-based primary care and participatory research during the COVID-19 pandemic in Bolivia.

β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy (2025)
Journal Article
Huo, Y., Shen, T., Feng, T., Li, M., Zhao, W., Loor, J., Aernouts, B., Psifidi, A., & Xu, C. (2025). β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy. Journal of Animal Science and Biotechnology, 16(1), https://doi.org/10.1186/s40104-024-01143-z

BackgroundIn perinatal dairy cows, ketosis is a prevalent metabolic disorder that lowers milk output and performance. Mitochondrial dysfunction and chronic inflammation in mammary tissue are linked to elevated blood ketone levels, particularly beta-h... Read More about β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.

Impact of commercial gut health interventions on caecal metagenome and broiler performance (2025)
Journal Article
Pangga, G., Star-Shirko, B., Psifidi, A., Xia, D., Corcionivoschi, N., Kelly, C., Hughes, C., Lavery, U., Richmond, A., Ijaz, U., & Gundogdu, O. (2025). Impact of commercial gut health interventions on caecal metagenome and broiler performance. Microbiome, 13(1), https://doi.org/10.1186/s40168-024-02012-7

BackgroundMaintaining gut health is a persistent and unresolved challenge in the poultry industry. Given the critical role of gut health in chicken performance and welfare, there is a pressing need to identify effective gut health intervention (GHI)... Read More about Impact of commercial gut health interventions on caecal metagenome and broiler performance.

Beagles kept as companion animals in the UK – demography, disorders and mortality (2025)
Journal Article
O'Neill, D., Schiksnis, M. R., Brodbelt, D. C., Church, D. B., Goldberg, S., & Engdahl, K. S. (2025). Beagles kept as companion animals in the UK – demography, disorders and mortality. Companion Animal Health and Genetics, 12(1), https://doi.org/10.1186/s40575-024-00140-9

Background Beagles are a popular companion animal dog breed and are generally stated to be a healthy breed.
This VetCompass study aimed to report the demography, common disorders and mortality of Beagles under primary
veterinary care in the UK. Ano... Read More about Beagles kept as companion animals in the UK – demography, disorders and mortality.

Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure (2025)
Journal Article
Tripathi, A., Jaiswal, A., Kumar, D., Pandit, R., Blake, D., Tomley, F., Joshi, M., Joshi, C., & Dubey, S. (2025). Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure. International Journal of Antimicrobial Agents, 65(3), https://doi.org/10.1016/j.ijantimicag.2025.107452

Background: Global demand for food has driven expansion and intensification of livestock production, particularly in developing nations where antibiotic use is often routine. Waste from poultry production, including manure, is commonly utilized as fe... Read More about Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure.