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Higher temperature extremes exacerbate negative disease effects in a social mammal (2022)
Journal Article
Paniw, M., Duncan, C., Groenewoud, F., Drewe, J., Manser, M., Ozgul, A., & Clutton-Brock, T. (2022). Higher temperature extremes exacerbate negative disease effects in a social mammal. Nature Climate Change, https://doi.org/10.1038/s41558-022-01284-x

One important but understudied way in which climate change may impact the fitness of individuals and populations is by altering the prevalence of infectious disease outbreaks. This is especially true in social species where endemic diseases are wides... Read More about Higher temperature extremes exacerbate negative disease effects in a social mammal.

Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data (2022)
Journal Article
Walker, M., Freitas, L. T., Halder, J. B., Brack, M., Keiser, J., King, C. H., …Basáñez, M. (in press). Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data. Wellcome Open Research, 7, 5. https://doi.org/10.12688/wellcomeopenres.17468.1

Response properties of optic flow neurons in the accessory optic system of hummingbirds versus zebra finches and pigeons (2022)
Journal Article
Gaede, A., Baliga, V., Smyth, G., Gutierrez-lbanez, C., Altshuler, D., & Wylie, D. (2022). Response properties of optic flow neurons in the accessory optic system of hummingbirds versus zebra finches and pigeons. Journal of Neurophysiology, 127(1), 130-144. https://doi.org/10.1152/jn.00437.2021

Optokinetic responses function to maintain retinal image stabilization by minimizing optic flow that occurs during self-motion. The hovering ability of hummingbirds is an extreme example of this behavior. Optokinetic responses are mediated by directi... Read More about Response properties of optic flow neurons in the accessory optic system of hummingbirds versus zebra finches and pigeons.

Successful Nonsurgical Management of a Traumatic Dens Fracture in a Cat with Clinical and Radiographic Resolution (2022)
Journal Article
von Hekkel, A., Watton, T., Fenn, J., & Phillips, A. (2022). Successful Nonsurgical Management of a Traumatic Dens Fracture in a Cat with Clinical and Radiographic Resolution. Journal of the American Animal Hospital Association, 58(1), 48-53. https://doi.org/10.5326/JAAHA-MS-7192

An adult domestic shorthair presented with obtundation, vestibular ataxia, head tilt, and visible evidence of facial injury following motor vehicle trauma. Plain radiographs and computed tomography imaging revealed a complete minimally displaced tran... Read More about Successful Nonsurgical Management of a Traumatic Dens Fracture in a Cat with Clinical and Radiographic Resolution.

Multifocal cryptococcosis diagnosis by peripheral lymph node aspirates in a cat (2022)
Journal Article
Butterfield, S., Matthias, C., Fenn, J., Szladovits, B., & Crawford, A. (2022). Multifocal cryptococcosis diagnosis by peripheral lymph node aspirates in a cat. Vet Record Case Reports, https://doi.org/10.1002/vrc2.259

A 4-year-old, female, neutered, domestic shorthair cat presented with a 5-day history of progressive inappetence, obtundation, vestibular ataxia and tetraparesis. Neurological examination findings on presentation were consistent with a multifocal loc... Read More about Multifocal cryptococcosis diagnosis by peripheral lymph node aspirates in a cat.

Surveillance of heat-related illness in small animals presenting to veterinary practices in the UK between 2013-2018. (2022)
Journal Article
Hall, E. (2022). Surveillance of heat-related illness in small animals presenting to veterinary practices in the UK between 2013-2018. Open Veterinary Journal, https://doi.org/10.5455/OVJ.2022.v12.i1.2

Background: Heat-related illness (HRI) can affect all companion animals and is likely to become more common as global temperatures rise. The misconception that HRI is primarily a result of dogs being trapped in hot cars, highlights a lack of awarenes... Read More about Surveillance of heat-related illness in small animals presenting to veterinary practices in the UK between 2013-2018..

Effects of Heat Stress on Follicular Physiology in Dairy Cows (2021)
Journal Article
De Rensis, F., Saleri, R., Garcia-Ispierto, I., Scaramuzzi, R., & Lopez-Gatius, F. (2021). Effects of Heat Stress on Follicular Physiology in Dairy Cows. Animals, 11(12), https://doi.org/10.3390/ani11123406

Simple Summary Environmentally induced hyperthermia, also called heat stress (HS), compromises reproductive physiology in mammals. The number of oocytes is fixed after birth and they are stored in the ovary in a quiescent state (at the stage of the f... Read More about Effects of Heat Stress on Follicular Physiology in Dairy Cows.

Towards a Better and Harmonized Education in Antimicrobial Stewardship in European Veterinary Curricula (2021)
Journal Article
PREPARE-VET Working Grp, ESCMID Study Grp Vet Microbiology, ESCMID Study Grp Antimicrobial ste, Espinosa-Gongora, C., Jessen, L., Dyar, O., …Guardabassi, L. (2021). Towards a Better and Harmonized Education in Antimicrobial Stewardship in European Veterinary Curricula. Antibiotics, 10(4), https://doi.org/10.3390/antibiotics10040364

Education in antimicrobial stewardship (AMS) in veterinary medicine is essential to foster responsible antimicrobial use and control of antimicrobial resistance (AMR) in animals. AMS is listed by the EU and international organizations among the basic... Read More about Towards a Better and Harmonized Education in Antimicrobial Stewardship in European Veterinary Curricula.

Effects of pimobendan in cats with hypertrophic cardiomyopathy and recent congestive heart failure: Results of a prospective, double-blind, randomized, nonpivotal, exploratory field study (2021)
Journal Article
Schober, K., Rush, J., Fuentes, V., Glaus, T., Summerfield, N., Wright, K., …Mohren, N. (2021). Effects of pimobendan in cats with hypertrophic cardiomyopathy and recent congestive heart failure: Results of a prospective, double-blind, randomized, nonpivotal, exploratory field study. Journal of Internal Medicine, 35(2), 789-800. https://doi.org/10.1111/jvim.16054

Background The benefits of pimobendan in the treatment of congestive heart failure (CHF) in cats with hypertrophic cardiomyopathy (HCM) have not been evaluated prospectively. Hypothesis/Objectives To investigate the effects of pimobendan in cats with... Read More about Effects of pimobendan in cats with hypertrophic cardiomyopathy and recent congestive heart failure: Results of a prospective, double-blind, randomized, nonpivotal, exploratory field study.

Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community (2021)
Journal Article
Mohamed, Y., Toizumi, M., Uematsu, M., Nguyen, H., Le, L., Takegata, M., …Yoshida, L. (2021). Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-020-79175-4

Conjunctival pneumococcal serotypes among members of a community have not been investigated well. We determined the prevalence and association of Streptococcus pneumoniae in the nasopharynx and conjunctiva among children in a community before pneumoc... Read More about Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community.

Spillover, hybridization, and persistence in schistosome transmission dynamics at the human-animal interface (2021)
Journal Article
Borlase, A., Rudge, J., Leger, E., Diouf, N., Fall, C., Diop, S., …Webster, J. (2021). Spillover, hybridization, and persistence in schistosome transmission dynamics at the human-animal interface. Proceedings of the National Academy of Sciences, 118(41), https://doi.org/10.1073/pnas.2110711118

Zoonotic spillover and hybridization of parasites are major emerging public and veterinary health concerns at the interface of infectious disease biology, evolution, and control. Schistosomiasis is a neglected tropical disease of global importance ca... Read More about Spillover, hybridization, and persistence in schistosome transmission dynamics at the human-animal interface.

Survey Design to Monitor Drug Efficacy for the Control of Soil-Transmitted Helminthiasis and Schistosomiasis (2021)
Journal Article
Coffeng, L., Levecke, B., Hattendorf, J., Walker, M., & Denwood, M. (2021). Survey Design to Monitor Drug Efficacy for the Control of Soil-Transmitted Helminthiasis and Schistosomiasis. Clinical Infectious Diseases, 72, S195-S202. https://doi.org/10.1093/cid/ciab196

Background. Control of soil-transmitted helminthiasis and schistosomiasis relies heavily on regular preventive chemotherapy. Monitoring drug efficacy is crucial to provide early warning of treatment failures. The World Health Organization (WHO) recom... Read More about Survey Design to Monitor Drug Efficacy for the Control of Soil-Transmitted Helminthiasis and Schistosomiasis.

Seroprevalence and associated risk factors of chikungunya, dengue, and Zika in eight districts in Tanzania (2021)
Journal Article
Mwanyika, G., Sindato, C., Rugarabamu, S., Rumisha, S., Karimuribo, E., Misinzo, G., …Mboera, L. (2021). Seroprevalence and associated risk factors of chikungunya, dengue, and Zika in eight districts in Tanzania. International Journal of Infectious Diseases, 111, 271-280. https://doi.org/10.1016/j.ijid.2021.08.040

Background: This study was conducted to determine the seroprevalence and risk factors of chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses in Tanzania. Methods: The study covered the districts of Buhigwe, Kalambo, Kilindi, Kinondoni, Kondoa... Read More about Seroprevalence and associated risk factors of chikungunya, dengue, and Zika in eight districts in Tanzania.

Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon (2021)
Journal Article
Finney, L., Glanville, N., Farne, H., Aniscenko, J., Fenwick, P., Kemp, S., …Singanayagam, A. (2021). Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon. Journal of Allergy and Clinical Immunology, 147(2), 510-+. https://doi.org/10.1016/j.jaci.2020.09.034

Background: The mechanisms underlying altered susceptibility and propensity to severe Coronavirus disease 2019 (COVID-19) disease in at-risk groups such as patients with chronic obstructive pulmonary disease (COPD) are poorly understood. Inhaled cort... Read More about Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon.

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor (2021)
Journal Article
Tan, M., Koussis, K., Withers-Martinez, C., Howell, S., Thomas, J., Hackett, F., …Blackman, M. (2021). Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor. EMBO Journal, 40(11), https://doi.org/10.15252/embj.2020107226

Malaria parasite egress from host erythrocytes (RBCs) is regulated by discharge of a parasite serine protease called SUB1 into the parasitophorous vacuole (PV). There, SUB1 activates a PV-resident cysteine protease called SERA6, enabling host RBC rup... Read More about Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.

Effects of larval rearing substrates on some life-table parameters of Lutzomyia longipalpis sand flies (2021)
Journal Article
Martins, K., Meirelles, M., Mota, T., Abbasi, I., de Queiroz, A., Brodskyn, C., …Warburg, A. (2021). Effects of larval rearing substrates on some life-table parameters of Lutzomyia longipalpis sand flies. PLoS Neglected Tropical Diseases, 15(1), https://doi.org/10.1371/journal.pntd.0009034

Sand flies are the insects responsible for transmitting Leishmania parasites, the causative agents of leishmaniasis in humans. However, the effects of sand fly breeding sites on their biology and ecology remain poorly understood. Herein, we studied h... Read More about Effects of larval rearing substrates on some life-table parameters of Lutzomyia longipalpis sand flies.

Genetic diversity within the 18S rRNA and actin locus of Cryptosporidium scrofarum (Apicomplexa: Cryptosporidiidae) infecting domestic pigs (Sus scrofa domesticus) of India (2021)
Journal Article
Sharma, D., Singh, N., Singh, H., Rath, S., & Blake, D. (2021). Genetic diversity within the 18S rRNA and actin locus of Cryptosporidium scrofarum (Apicomplexa: Cryptosporidiidae) infecting domestic pigs (Sus scrofa domesticus) of India. Veterinarski Arhiv, 91(3), 269-276. https://doi.org/10.24099/vet.arhiv.0674

The genetic diversity was studied of Cryptosporidium scrofarum (syn Cryptosporidium pig genotype II) of domestic pigs (Sus scrofa domesticus) from Punjab, India. Nested PCR amplification targeting the 18S rRNA and actin gene loci from Cryptosporidium... Read More about Genetic diversity within the 18S rRNA and actin locus of Cryptosporidium scrofarum (Apicomplexa: Cryptosporidiidae) infecting domestic pigs (Sus scrofa domesticus) of India.

Transmission Dynamics of African Swine Fever Virus, South Korea, 2019 (2021)
Journal Article
Yoo, D., Kim, Y., Lee, E., Lim, J., Hong, S., Lee, I., …Fournie, G. (2021). Transmission Dynamics of African Swine Fever Virus, South Korea, 2019. Emerging Infectious Disease, 27(7), 1909-1918. https://doi.org/10.3201/eid2707.204230

African swine fever (ASF) is a substantial concern for global food production and security. However, lack of epidemiologic data in affected areas has limited the knowledge of the main drivers of ASF virus (ASFV) transmission. To assess the role of ve... Read More about Transmission Dynamics of African Swine Fever Virus, South Korea, 2019.

Advances in managing pregnancy toxaemia in sheep (2021)
Journal Article
Crilly, J., Phythian, C., & Evans, M. (2021). Advances in managing pregnancy toxaemia in sheep. In Practice, 43(2), 79-94. https://doi.org/10.1002/inpr.17

Background: Ovine pregnancy toxaemia (OPT) is a metabolic disorder of ewes in late pregnancy. Cases are typically seen in ewes carrying multiple fetuses, hence the alternative name of 'twin lamb disease'. The disease has been well known for many year... Read More about Advances in managing pregnancy toxaemia in sheep.

Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection (2021)
Journal Article
Al-Neama, R., Bown, K., Blake, D., & Birtles, R. (2021). Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection. Parasitology, 148(5), 623-629. https://doi.org/10.1017/S0031182021000044

Coccidiosis caused by Eimeria species is a well-recognized disease of livestock. Enteric Eimeria infections are common, but disease usually only manifests when infection intensity is abnormally high. Campylobacter species are important zoonotic enter... Read More about Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection.