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Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor (2021)
Journal Article
Pang, K. T., Ghim, M., Liu, C., Tay, H. M., Fhu, C. W., Chia, R. N., …Wang, X. (2021). Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor. Frontiers in Cell and Developmental Biology, 9, https://doi.org/10.3389/fcell.2021.706143

Elevated serum concentrations of leucine-rich α-2-glycoprotein (LRG1) have been reported in patients with inflammatory, autoimmune, and cardiovascular diseases. This study aims to investigate the role of LRG1 in endothelial activation. LRG1 in endoth... Read More about Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor.

Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus (2021)
Journal Article
Leite, R. F., Gonçalves, J. L., Buanz, A., Febraro, C., Craig, D., Van Winden, S., …Santos, M. V. (in press). Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus. Journal of Dairy Science, https://doi.org/10.3168/jdsc.2021-0114

Polyhexamethylene biguanide (PHMB) nanoparticles (NP) developed for this study presented antimicrobial activity against mastitis-causing Staphylococcus aureus at lower concentrations than PHMB alone, chlorhexidine digluconate, povidone-iodine, and so... Read More about Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus.

A new LC/MS method for specific determination of human systemic exposure to bisphenol A, F and S through their metabolites: Application to cord blood samples (2021)
Journal Article
Gély, C., Huesca, A., Picard-Hagen, N., Toutain, P., Berrebi, A., Gauderat, G., …Lacroix, M. (2021). A new LC/MS method for specific determination of human systemic exposure to bisphenol A, F and S through their metabolites: Application to cord blood samples. Environment International, 151, 106429. https://doi.org/10.1016/j.envint.2021.106429

Changing Veterinary Attitudes towards Delivering Biosecurity Advice to Beef Farmers (2021)
Journal Article
Howarth, B. E., & van Winden, S. (2021). Changing Veterinary Attitudes towards Delivering Biosecurity Advice to Beef Farmers. Animals, 11(7), 1969. https://doi.org/10.3390/ani11071969

Biosecurity advice is an important way veterinarians can help farmers to reduce disease burdens on their farms. Many different factors are at play when delivering this advice, one being veterinary competence and their communication skills. This study... Read More about Changing Veterinary Attitudes towards Delivering Biosecurity Advice to Beef Farmers.

Pharmacokinetics of colistin in the gastrointestinal tract of poultry following dosing via drinking water, and the bactericidal impact on enteric E. coli. (2021)
Journal Article
Mead, A., Richez, P., Azzariti, S., & Pelligand, L. (2021). Pharmacokinetics of colistin in the gastrointestinal tract of poultry following dosing via drinking water, and the bactericidal impact on enteric E. coli. Frontiers in Veterinary Science,

Colistin, a last line antibiotic of major importance in veterinary medicine and critical importance in human medicine, is authorised to treat gastrointestinal (enteric) infections caused by non-invasive E. coli in multiple veterinary species includin... Read More about Pharmacokinetics of colistin in the gastrointestinal tract of poultry following dosing via drinking water, and the bactericidal impact on enteric E. coli..

Vetreccr R1 Text Final AL 27May21 (2021)
Journal Article
Loeffler, A., Boone, J., Boone, J., Fountain, K., Williams, J., Lloyd, D. H., …Loeffler, A. (in press). Vetreccr R1 Text Final AL 27May21. Veterinary Record,

Pinnae are vital structures for echolocation and survival in many species of bats. Pinnal lesions have been described as common in captive bats, but information on specific diseases affecting the pinnae is scarce. A collection of histological section... Read More about Vetreccr R1 Text Final AL 27May21.

Building an ecologically founded disease risk prioritization framework for migratory wildlife species based on contact with livestock (2021)
Journal Article
Khanyari, M., Robinson, S., E., M., Singh N. J., Brown, T., Salemgareyev, A., …Kock, R. (in press). Building an ecologically founded disease risk prioritization framework for migratory wildlife species based on contact with livestock. Journal of Applied Ecology, 00, 1-16. https://doi.org/10.1111/1365-2664.13937

Coccidiosis, caused by Eimeria species parasites, remains a major threat to poultry production, undermining economic performance and compromising welfare. The recent characterization of three new Eimeria species that infect chickens has highlighted t... Read More about Building an ecologically founded disease risk prioritization framework for migratory wildlife species based on contact with livestock.

The use of ondansetron for the treatment of nausea in dogs with vestibular syndrome (2021)
Journal Article
Foth, S., Meller, S., Kenward, H., Elliott, J., Pelligand, L., & Volk, H. (2021). The use of ondansetron for the treatment of nausea in dogs with vestibular syndrome. BMC Veterinary Research, 17(1), https://doi.org/10.1186/s12917-021-02931-9

Background Vestibular syndrome is often accompanied by nausea. Drugs currently approved for its treatment have been developed to stop vomiting but not nausea. The efficacy of 5-HT3 receptor antagonists to reduce nausea has been described for chemothe... Read More about The use of ondansetron for the treatment of nausea in dogs with vestibular syndrome.

Challenges to exotic disease preparedness in Great Britain: the frontline veterinarian's perspective (2021)
Journal Article
Cardwell, J., Spence, K., Rosanowski, S., & Slater, J. (2021). Challenges to exotic disease preparedness in Great Britain: the frontline veterinarian's perspective. Equine Veterinary Journal,

Background: Exotic diseases pose a significant risk to horse health and welfare. Several stakeholder groups, including primary care veterinarians, share responsibility for maintaining freedom from pathogens that cause exotic diseases. However, little... Read More about Challenges to exotic disease preparedness in Great Britain: the frontline veterinarian's perspective.

Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits (2021)
Journal Article
Sweet-Jones, J., Lenis, V. P., Yurchenko, A. A., Yudin, N. S., Swain, M., & Larkin, D. M. (2021). Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits. Frontiers in Genetics, 12, https://doi.org/10.3389/fgene.2021.612492

Background: Advances in genetic tools applied to livestock breeding has prompted research into the previously neglected breeds adapted to harsh local environments. One such group is the Welsh mountain sheep breeds, which can be farmed at altitudes of... Read More about Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits.

Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken (2021)
Journal Article
Abeyesinghe, S., Abeyesinghe, S., Chancellor, N., Hernandez Moore, D., Chang, Y., Pearce, J., …Nicol, C. (2021). Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken. animal, 15(7), Article 100261. https://doi.org/10.1016/j.animal.2021.100261

Broiler chickens are prone to a range of complex health and welfare issues. To support informed selection of welfare traits whilst minimising impact on production efficiency and to address a major gap in understanding, we systematically explored asso... Read More about Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken.

Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis (2021)
Journal Article
Cheng, Z., Buggiotti, L., Salavati, M., Marchitelli, C., Palma-Vera, S., Wylie, A., …GplusE Consortium. (in press). Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis. Molecular Biology Reports,

Bovine mastitis is an inflammatory disease of the mammary gland, which is classified as subclinical or clinical. Circulating neutrophils are recruited to the udder to help combat infection. We compared the transcriptomic profiles in circulating leuko... Read More about Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis.

The plate-to-rod transition in trabecular bone loss is elusive (2021)
Journal Article
Felder, A. A., Monzem, S., De Souza, R., Javaheri, B., Mills, D., Boyde, A., & Doube, M. (2021). The plate-to-rod transition in trabecular bone loss is elusive. Royal Society Open Science, 8(6), 201401. https://doi.org/10.1098/rsos.201401

Changes in trabecular micro-architecture are key to our understanding of osteoporosis. Previous work focusing on structure model index (SMI) measurements have concluded that disease progression entails a shift from plates to rods in trabecular bone,... Read More about The plate-to-rod transition in trabecular bone loss is elusive.

An ethical framework for the use of horses in competitive sport: theory and function (2021)
Journal Article
Campbell, M. (2021). An ethical framework for the use of horses in competitive sport: theory and function. Animals, https://doi.org/10.3390/ani11061725

Growing ethical concern about equestrian sport is reflected in publications by regulatory authorities, animal charities, and the lay press; and in government debate and social media. However, attempts by regulators and stakeholders to address ethica... Read More about An ethical framework for the use of horses in competitive sport: theory and function.

The evolutionary biomechanics of locomotor function in giant land animals (2021)
Journal Article
Hutchinson, J. (2021). The evolutionary biomechanics of locomotor function in giant land animals. Journal of Experimental Biology, https://doi.org/10.1242/jeb.217463

Giant land vertebrates have evolved more than 30 times, notably in dinosaurs and mammals. The evolutionary and biomechanical perspectives considered here unify data from extant and extinct species, assessing current theory regarding how the locomotor... Read More about The evolutionary biomechanics of locomotor function in giant land animals.