James Sweet-Jones
Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits
Sweet-Jones, James; Lenis, Vasileios Panagiotis; Yurchenko, Andrey A.; Yudin, Nikolay S.; Swain, Martin; Larkin, Denis M.
Authors
Vasileios Panagiotis Lenis
Andrey A. Yurchenko
Nikolay S. Yudin
Martin Swain
Denis M. Larkin
Contributors
Denis Larkin
Supervisor
Abstract
Background: Advances in genetic tools applied to livestock breeding has prompted research into the previously neglected breeds adapted to harsh local environments. One such group is the Welsh mountain sheep breeds, which can be farmed at altitudes of 300 m above sea level but are considered to have a low productive value because of their poor wool quality and small carcass size. This is contrary to the lowland breeds which are more suited to wool and meat production qualities, but do not fare well on upland pasture. Herein, medium-density genotyping data from 317 individuals representing 15 Welsh sheep breeds were used alongside the whole-genome resequencing data of 14 breeds from the same set to scan for the signatures of selection and candidate genetic variants using haplotype-and SNP-based approaches.
Citation
Sweet-Jones, J., Lenis, V. P., Yurchenko, A. A., Yudin, N. S., Swain, M., & Larkin, D. M. (2021). Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits. Frontiers in Genetics, 12, https://doi.org/10.3389/fgene.2021.612492
Journal Article Type | Article |
---|---|
Acceptance Date | May 10, 2021 |
Online Publication Date | Jun 18, 2021 |
Publication Date | Jun 18, 2021 |
Deposit Date | Jul 4, 2021 |
Publicly Available Date | Jul 14, 2021 |
Journal | Frontiers in Genetics |
Electronic ISSN | 1664-8021 |
Publisher | Frontiers Media |
Peer Reviewed | Peer Reviewed |
Volume | 12 |
DOI | https://doi.org/10.3389/fgene.2021.612492 |
Keywords | Genetics(clinical); Molecular Medicine; Genetics |
Public URL | https://rvc-repository.worktribe.com/output/1549676 |
Files
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Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/
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