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All Outputs (452)

Developing teaching to improve the wellbeing of future vets (2017)
Journal Article
Armitage-Chan, E. (2017). Developing teaching to improve the wellbeing of future vets. Veterinary Record, 181(1), https://doi.org/10.1136/vr.j3109

Some people are under the impression that developing the educational experience of students at the Royal Veterinary College doesn't make you a ‘real vet’. Here, Elizabeth Armitage-Chan explains how her role helps future vets gain in confidence and co... Read More about Developing teaching to improve the wellbeing of future vets.

Phenotypic heterogeneity of peripheral monocytes in healthy dogs (2017)
Journal Article
Gibbons, N., Goulart, M. R., Chang, Y. M., Efstathiou, K., Purcell, R., Wu, Y., …Garden, O. A. (2017). Phenotypic heterogeneity of peripheral monocytes in healthy dogs. Veterinary Immunology and Immunopathology, 190, 26-30. https://doi.org/10.1016/j.vetimm.2017.06.007

Monocytes are key cells of the innate immune system. Their phenotypic and functional roles have been investigated in humans, mice and other animals, such as the rat, pig and cow. To date, detailed phenotypic analysis of monocytes has not been underta... Read More about Phenotypic heterogeneity of peripheral monocytes in healthy dogs.

A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling (2017)
Journal Article
Gatliff, J., East, D. A., Singh, A., Alvarez, M. S., Frison, M., Matic, I., …Campanella, M. (2017). A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling. https://doi.org/10.1038/cddis.2017.186

The 18 kDa translocator protein TSPO localizes on the outer mitochondrial membrane (OMM). Systematically overexpressed at sites of neuroinflammation it is adopted as a biomarker of brain conditions. TSPO inhibits the autophagic removal of mitochondri... Read More about A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling.

Morphology and the gradient of a symmetric potential predicts gait transitions of dogs (2017)
Journal Article
Wilshin, S. D., Haynes, G. C., Porteous, J., Koditschek, D., Revzen, S., & Spence, A. J. (2017). Morphology and the gradient of a symmetric potential predicts gait transitions of dogs. Biological Cybernetics, 111(3-4), 269-277. https://doi.org/10.1007/s00422-017-0721-2

Gaits and gait transitions play a central role in the movement of animals. Symmetry is thought to govern the structure of the nervous system, and constrain the limb motions of quadrupeds. We quantify the symmetry of dog gaits with respect to combinat... Read More about Morphology and the gradient of a symmetric potential predicts gait transitions of dogs.

Variants in the 3'UTR of the ovine Acetyl-Coenzyme A Acyltransferase 2 gene are associated with dairy traits and exhibit differential allelic expression (2017)
Journal Article
Miltiadou, D., Hager-Theodorides, A., Symeou, S., Constantinou, C., Psifidi, A., Banos, G., & Tzamaloukas, O. (2017). Variants in the 3'UTR of the ovine Acetyl-Coenzyme A Acyltransferase 2 gene are associated with dairy traits and exhibit differential allelic expression. Journal of Dairy Science, 100(8), 6285-6297. https://doi.org/10.3168/jds.2016-12326

The acetyl-CoA acyltransferase 2 (ACAA2) gene encodes an enzyme of the thiolase family that is involved in mitochondrial fatty acid elongation and degradation by catalyzing the last step of the respective β-oxidation pathway. The increased energy nee... Read More about Variants in the 3'UTR of the ovine Acetyl-Coenzyme A Acyltransferase 2 gene are associated with dairy traits and exhibit differential allelic expression.

Combination of magnesium sulphate and ropivacaine epidural analgesia for hip arthroplasty in dogs (2017)
Journal Article
Lardonea, E., Peironea, B., & Adami, C. (2017). Combination of magnesium sulphate and ropivacaine epidural analgesia for hip arthroplasty in dogs. Veterinary Anaesthesia and Analgesia, 44(5), 1227-1235. https://doi.org/10.1016/j.vaa.2016.11.016

The aim of this study was to determine whether lumbosacral epidural administration of magnesium sulphate added to ropivacaine prolongs and improves perioperative analgesia, without adverse effects on motor block duration or hind limb neurologica... Read More about Combination of magnesium sulphate and ropivacaine epidural analgesia for hip arthroplasty in dogs.

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study (2017)
Journal Article
Noyce, A. J., Kia, D. A., Hemani, G., Nicolas, A., Price, T. R., De Pablo-Fernandez, E., …Wood, N. W. (2017). Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. PLoS Medicine, 14(6), https://doi.org/10.1371/journal.pmed.1002314

Both positive and negative associations between higher body mass index (BMI) and Parkinson disease (PD) have been reported in observational studies, but it has been difficult to establish causality because of the possibility of residual confounding o... Read More about Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.