Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185

Holder, A L; Jones, G; Soutter, F; Palmer, D B; Aspinall, R; Catchpole, B

doi:10.1016/j.dci.2017.12.008

Occurrence of preterm calving in Great Britain and associations with milk production and reproductive performance in dairy cattle (2018)
Journal Article
Damaso, A. F., Velasova, M., Van Winden, S. C. L., Chang, Y. M., & Guitian, J. (2018). Occurrence of preterm calving in Great Britain and associations with milk production and reproductive performance in dairy cattle. Veterinary Record Open, 5, e000221. https://doi.org/10.1136/vetreco-2017-000221

This study describes the occurrence of preterm calving in Great Britain and evaluates its associations with subsequent milk production and reproductive performances and survival on farm of dairy cows. A total of 53 British dairy farms and 5759 animal... Read More about Occurrence of preterm calving in Great Britain and associations with milk production and reproductive performance in dairy cattle.

Effect of melatonin supplementation in the long-term preservation of the sheep ovaries at different temperatures and subsequent in vitro embryo production (2018)
Journal Article
Goodarzi, A., Zare Shahneh, A., Kohram, H., Sadeghi, M., Moazenizadeh, M. H., Fouladi-Nashta, A. A., & Dadashpour Davachi, N. (2018). Effect of melatonin supplementation in the long-term preservation of the sheep ovaries at different temperatures and subsequent in vitro embryo production. Theriogenology, 106, 265-270. https://doi.org/10.1016/j.theriogenology.2017.10.009

Investigations in the past decades have shown that oocytes developmental competence following in vitro fertilization is greatly influenced by an interval between isolation of the ovaries immediately after death/slaughter and oocytes recovery from the... Read More about Effect of melatonin supplementation in the long-term preservation of the sheep ovaries at different temperatures and subsequent in vitro embryo production.

Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo (2018)
Journal Article
Nair, S., Sobotka, K. S., Joshi, P., Gressens, P., Fleiss, B., Thornton, C., …Hagberg, H. (2018). Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo. Glia, https://doi.org/10.1002/glia.23587

Accumulating evidence suggests that changes in the metabolic signature of microglia underlie their response to inflammation. We sought to increase our knowledge of how pro‐inflammatory stimuli induce metabolic changes. Primary microglia exposed to li... Read More about Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo.

Mitochondrial calcium imbalance in Parkinson's disease (2018)
Journal Article
Ludtmann, M. H. R., & Abramov, A. Y. (2018). Mitochondrial calcium imbalance in Parkinson's disease. Neuroscience Letters, 663, 8690. https://doi.org/10.1016/j.neulet.2017.08.044

Multiple factors are involved in the mechanism(s) of neuronal loss in neurodegenerative disorders whilst mitochondria are thought to play a central role in neurodegeneration of Parkinson’s disease. Mitochondria are vital to cellular functions by supp... Read More about Mitochondrial calcium imbalance in Parkinson's disease.

Hip joint articular soft tissues of non-dinosaurian Dinosauromorpha and early Dinosauria: evolutionary and biomechanical implications for Saurischia (2018)
Journal Article
Tsai, H. P., Middleton, K. M., Hutchinson, J. R., & Holliday, C. M. (2018). Hip joint articular soft tissues of non-dinosaurian Dinosauromorpha and early Dinosauria: evolutionary and biomechanical implications for Saurischia. Journal of Vertebrate Paleontology, 38(1), https://doi.org/10.1080/02724634.2017.1427593

Dinosauromorphs evolved a wide diversity of hind limb skeletal morphologies, suggesting highly divergent articular soft tissue anatomies. However, poor preservation of articular soft tissues in fossils has hampered any follow-on functional inferences... Read More about Hip joint articular soft tissues of non-dinosaurian Dinosauromorpha and early Dinosauria: evolutionary and biomechanical implications for Saurischia.

Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae) (2018)
Journal Article
Michaels, C. J., Das, S., Chang, Y. M., & Tapley, B. (2018). Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae)

Aquatic predators must forage for prey in a complex three-dimensional environment where the availability of different prey types with different spatial niches may vary. Aquatic predators have evolved a number of ways in which they may respond to this... Read More about Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae).

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists (2018)
Journal Article
Mabilleau, G., Pereira, M., & Chenu, C. (2018). Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists. Journal of Endocrinology, 236, R29-R42. https://doi.org/10.1530/JOE-17-0278

Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications. In addition, some anti-diabetic therapies for T2DM can have notable detrimental skeletal effect... Read More about Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists.

Plasma adrenocorticotropic hormone (ACTH) concentrations in ponies measured by two different assays suggests seasonal cross reactivity or interference (2018)
Journal Article
Knowles, E. J., Moreton-Clack, M. C., Shaw, S., Harris, P. A., Elliott, J., & Menzies-Gow, N. J. (2018). Plasma adrenocorticotropic hormone (ACTH) concentrations in ponies measured by two different assays suggests seasonal cross reactivity or interference. Equine Veterinary Journal, 50(5), 672-677. https://doi.org/10.1111/evj.12797

Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185 (2018)
Journal Article
Holder, A. L., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R., & Catchpole, B. (2018). Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185. Developmental and Comparative Immunology, 81, 244-251. https://doi.org/10.1016/j.dci.2017.12.008

Interleukin-7 (IL-7) and its receptor (IL-7R) are essential for T cell development in the thymus, and changes in the IL-7/IL-7R pathway have been implicated in age-associated thymic involution which results in a reduction of naïve T cell output. The... Read More about Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185.

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