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Preliminary assessment of cognitive impairments in canine idiopathic epilepsy (2018)
Journal Article
Winter, J., Packer, R. M. A., & Volk, H. A. (2018). Preliminary assessment of cognitive impairments in canine idiopathic epilepsy. Veterinary Record, https://doi.org/10.1136/vr.104603

In humans, epilepsy can induce or accelerate cognitive impairment (CI). There is emerging evidence of CI in dogs with idiopathic epilepsy (IE) from recent epidemiological studies. The aim of our study was to assess CI in dogs with IE using two tests... Read More about Preliminary assessment of cognitive impairments in canine idiopathic epilepsy.

Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter (2018)
Journal Article
Read, J. E., Cabrera-Sharp, V., Kitscha, P., Cartwright, J. E., King, P. J., Fowkes, R. C., & De Mestre, A. M. (2018). Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter. Frontiers in Endocrinology, 9, https://doi.org/10.3389/fendo.2018.00195

Equine chorionic gonadotrophin (eCG) is a placental glycoprotein critical for early equine pregnancy and used therapeutically in a number of species to support reproductive activity. The factors in trophoblast that transcriptionally regulate eCGβ-sub... Read More about Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter.

Chromosome Segregation Is Biased by Kinetochore Size (2018)
Journal Article
Drpic, D., Almeida, A. C., Aguiar, P., Renda, F., Damas, J., Lewin, H. A., …Maiato, H. (2018). Chromosome Segregation Is Biased by Kinetochore Size. Current Biology, 28(9), 1344-1365. https://doi.org/10.1016/j.cub.2018.03.023

Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selectio... Read More about Chromosome Segregation Is Biased by Kinetochore Size.

Movement patterns and athletic performance of leopards in the Okavango Delta (2018)
Journal Article
Hubel, T. Y., Golabek, K. A., Rafiq, K., Weldon McNutt, J., & Wilson, A. M. (2018). Movement patterns and athletic performance of leopards in the Okavango Delta. Proceedings of the Royal Society B: Biological Sciences, 285(4), 1017-1027. https://doi.org/10.1098/rspb.2017.2622

Although leopards are the most widespread of all the big cats and are known for their adaptability, they are elusive and little is known in detail about their movement and hunting energetics. We used high-resolution GPS/IMU (inertial measurement unit... Read More about Movement patterns and athletic performance of leopards in the Okavango Delta.

Interaction with macrophages attenuates equine fibroblast-like synoviocyte ADAMTS5 (aggrecanase-2) gene expression following inflammatory stimulation: MACROPHAGES ATTENUATE SYNOVIAL FIBROBLAST RESPONSE (2018)
Journal Article
Morgan, R. E., Clegg, P. D., Hunt, J. A., Innes, J. F., & Tew, S. R. (2018). Interaction with macrophages attenuates equine fibroblast-like synoviocyte ADAMTS5 (aggrecanase-2) gene expression following inflammatory stimulation: MACROPHAGES ATTENUATE SYNOVIAL FIBROBLAST RESPONSE. Journal of Orthopaedic Research, 36(8), 2178-2185. https://doi.org/10.1002/jor.23891

A study of the pharmacokinetics and thromboxane inhibitory activity of a single intramuscular dose of carprofen as a means to establish its potential use as an analgesic drug in white rhinoceros (2018)
Journal Article
Leiberich, M., Krebber, R., Hewetson, M., Marais, J., & Naidoo, V. (2018). A study of the pharmacokinetics and thromboxane inhibitory activity of a single intramuscular dose of carprofen as a means to establish its potential use as an analgesic drug in white rhinoceros. Journal of Veterinary Pharmacology and Therapeutics, 41(4), 605-613. https://doi.org/10.1111/jvp.12508

The alleviation of pain and prevention of suffering are key aspects of animal welfare. Unfortunately, analgesic drugs are not available for all species. White rhinoceros (Ceratotherium simum), representing one of such species, which survive poaching... Read More about A study of the pharmacokinetics and thromboxane inhibitory activity of a single intramuscular dose of carprofen as a means to establish its potential use as an analgesic drug in white rhinoceros.

Pathological classification of equine recurrent laryngeal neuropathy (2018)
Journal Article
Draper, A. C. E., & Piercy, R. J. (2018). Pathological classification of equine recurrent laryngeal neuropathy. Journal of Veterinary Internal Medicine, 32(4), 1397-1409. https://doi.org/10.1111/jvim.15142

Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left‐sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle p... Read More about Pathological classification of equine recurrent laryngeal neuropathy.

The applicability of animal health surveillance systems for post-market monitoring of potential adverse effects of genetically modified (GM) feed (2018)
Journal Article
Vince, L., Kleter, G. A., Kostov, K., Pfeiffer, D. U., & Guitian, J. (2018). The applicability of animal health surveillance systems for post-market monitoring of potential adverse effects of genetically modified (GM) feed. Food and Chemical Toxicology, https://doi.org/10.1016/j.fct.2018.04.034

A facultative post market monitoring of potential health impacts of genetically modified (GM) feedstuffs on livestock consuming these feeds after pre-market risk assessment is under ongoing consideration. Within the IPAFEED database, scientific studi... Read More about The applicability of animal health surveillance systems for post-market monitoring of potential adverse effects of genetically modified (GM) feed.

Risk-based inspection as a cost-effective strategy to reduce human exposure to cysticerci of Taenia saginata in low-prevalence settings (2018)
Journal Article
Prakashbabu, B. C., Marshall, L. R., Crotta, M., Gilbert, W., Johnson, J. C., Alban, L., & Guitian, J. (2018). Risk-based inspection as a cost-effective strategy to reduce human exposure to cysticerci of Taenia saginata in low-prevalence settings. https://doi.org/10.1186/s13071-018-2839-z

Taenia saginata cysticercus is the larval stage of the zoonotic parasite Taenia saginata, with a life-cycle involving both cattle and humans. The public health impact is considered low. The current surveillance system, based on post-mortem inspection... Read More about Risk-based inspection as a cost-effective strategy to reduce human exposure to cysticerci of Taenia saginata in low-prevalence settings.

The phospholipase A2 pathway controls a synaptic cholesterol ester cycle and synapse damage (2018)
Journal Article
Osborne, C., West, E., & Bate, C. (2018). The phospholipase A2 pathway controls a synaptic cholesterol ester cycle and synapse damage. Journal of Cell Science, 131(8), https://doi.org/10.1242/jcs.211789

The cellular prion protein (PrPC) acts as a scaffold protein that organises signalling complexes. In synaptosomes, the aggregation of PrPC by amyloid-β (Aβ) oligomers attracts and activates cytoplasmic phospholipase A2 (cPLA2), leading to synapse deg... Read More about The phospholipase A2 pathway controls a synaptic cholesterol ester cycle and synapse damage.

Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling (2018)
Journal Article
Al-Rashed, F., Calay, D., Lang, M., Thornton, C., Bauer, A., Kiprianos, A., …Mason, J. C. (2018). Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling. https://doi.org/10.1038/s41598-018-24548-z

Although concern remains about the athero-thrombotic risk posed by cyclo-oxygenase (COX)-2-selective inhibitors, recent data implicates rofecoxib, while celecoxib appears equivalent to NSAIDs naproxen and ibuprofen. We investigated the hypothesis tha... Read More about Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling.

Phylogenetic relationships within the Opisthorchis viverrini species complex with specific analysis of O. viverrini sensu lato from Sakon Nakhon, Thailand by mitochondrial and nuclear DNA sequencing (2018)
Journal Article
Pitaksakulrat, O., Webster, B. L., Webster, J. P., Laha, T., Saijuntha, W., Lamberton, P. H. L., …Sithithaworn, P. (2018). Phylogenetic relationships within the Opisthorchis viverrini species complex with specific analysis of O. viverrini sensu lato from Sakon Nakhon, Thailand by mitochondrial and nuclear DNA sequencing. https://doi.org/10.1016/j.meegid.2018.04.022

The liver fluke Opisthorchis viverrini sensu lato causes serious public-health problems in Northeast Thailand and Southeast Asian countries. A hypothesis has been proposed that O. viverrini represents a species complex with varying levels of genetic... Read More about Phylogenetic relationships within the Opisthorchis viverrini species complex with specific analysis of O. viverrini sensu lato from Sakon Nakhon, Thailand by mitochondrial and nuclear DNA sequencing.

Diabetes mellitus remission in a cat with pituitary-dependent hyperadrenocorticism after trilostane treatment (2018)
Journal Article
Muschner, A. C., Varela, F. V., Hazuchova, K., & Niessen, S. J. M. (2018). Diabetes mellitus remission in a cat with pituitary-dependent hyperadrenocorticism after trilostane treatment. Journal of Feline Medicine and Surgery Open Reports, 4(1), https://doi.org/10.1177/2055116918767708

An 8-year-old male neutered Persian cat was presented with polyuria, polydipsia, polyphagia and muscle weakness associated with a 7 month history of diabetes mellitus (DM). The cat had initially been treated with neutral protamine Hagedorn (NPH) insu... Read More about Diabetes mellitus remission in a cat with pituitary-dependent hyperadrenocorticism after trilostane treatment.

International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study (2018)
Journal Article
Fox, P. R., Keene, B. W., Lamb, K., Schober, K. A., Chetboul, V., Fuentes, V. L., …Ohara, V. Y. T. (2018). International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study. Journal of Veterinary Internal Medicine, 32(3), 930-943. https://doi.org/10.1111/jvim.15122

Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers (2018)
Journal Article
Beever, L., Swinbourne, F., Priestnall, S. L., Ter Haar, G., & Brockman, D. J. (2018). Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers. Journal of Small Animal Practice, 60(4), 254-260. https://doi.org/10.1111/jsap.12839

Three West Highland white terriers were presented for investigation of left‐sided para‐aural abscessation. CT revealed chronic otitis media with extensive osseous proliferation surrounding the horizontal and vertical ear canals contiguous with the ex... Read More about Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers.

Eimeria spp. in captive-reared corncrakes (Crex crex): results of GeneScan assay consistent with high prevalence of infection and extra-intestinal life stages (2018)
Journal Article
Serna, H., Pocknell, A., Sainsbury, A. W., Peniche, G., Blake, D. P., & Beckmann, K. M. (2018). Eimeria spp. in captive-reared corncrakes (Crex crex): results of GeneScan assay consistent with high prevalence of infection and extra-intestinal life stages. Avian Pathology, https://doi.org/10.1080/03079457.2018.1451621

Eimeria crecis and Eimeria nenei have been detected in association with enteric disease (‘coccidiosis’) in the corncrake (Crex crex: Family Rallidae, Order Gruiformes). Both parasite species are common in apparently healthy free-living corncrakes, bu... Read More about Eimeria spp. in captive-reared corncrakes (Crex crex): results of GeneScan assay consistent with high prevalence of infection and extra-intestinal life stages.

Local back pressure caused by a training roller during lunging with and without a Pessoa training aid (2018)
Journal Article
Mackechnie-Guire, R., Mackechnie-Guire, E., Bush, R., Fisher, D., Fisher, M., & Weller, R. (2018). Local back pressure caused by a training roller during lunging with and without a Pessoa training aid. Journal of Equine Veterinary Science, 67, 112-117. https://doi.org/10.1016/j.jevs.2018.03.018

Ground schooling (especially lunging) is routinely performed in the rehabilitation and training of horses. Training rollers are commonly used to provide attachment for training aids. The objective of the study was to objectively measure pressures ben... Read More about Local back pressure caused by a training roller during lunging with and without a Pessoa training aid.

Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in weanling foals (2018)
Journal Article
Hewetson, M., Venner, M., Volquardsen, J., Sykes, B., Hallowell, G., Vervuert, I., …Tulamo, R. M. (2018). Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in weanling foals. Acta Veterinaria Scandinavica, 60, 24. https://doi.org/10.1186/s13028-018-0377-5

Equine gastric ulcer syndrome is an important cause of morbidity in weanling foals. Many foals are asymptomatic, and the development of an inexpensive screening test to ensure an early diagnosis is desirable. The objective of this study was to determ... Read More about Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in weanling foals.