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TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia-Ischemia (2018)
Journal Article
Kichev, A., Baburamani, A. A., Vontell, R., Gressens, P., Burkly, L., Thornton, C., & Hagberg, H. (2018). TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia-Ischemia. Frontiers in Neurology, 9(230), https://doi.org/10.3389/fneur.2018.00230

Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a multifunctional cytokine member of the TNF family. TWEAK binds to its only known receptor, Fn14, enabling it to activate downstream signaling processes in response to tissue inju... Read More about TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia-Ischemia.

Canine NAPEPLD-associated models of human myelin disorders (2018)
Journal Article
Minor, K. M., Letko, A., Becker, D., Drogemuller, M., Mandigers, P. J. J., Bellekom, S. R., …Drogemuller, C. (2018). Canine NAPEPLD-associated models of human myelin disorders. https://doi.org/10.1038/s41598-018-23938-7

Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to... Read More about Canine NAPEPLD-associated models of human myelin disorders.

A randomized, blinded, prospective clinical trial of postoperative rehabilitation in dogs after surgical decompression of acute thoracolumbar intervertebral disc herniation (2018)
Journal Article
Zidan, N., Sims, C., Fenn, J., Williams, K., Griffith, E., Early, P. J., …Olby, N. J. (2018). A randomized, blinded, prospective clinical trial of postoperative rehabilitation in dogs after surgical decompression of acute thoracolumbar intervertebral disc herniation. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15086

The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk? (2018)
Journal Article
Rosanowski, S. M., Banica, M., Ellis, E., Farrow, E., Harwood, C., Jordan, B., …Blake, D. P. (2018). The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk?. Parasitology Research, 117(5), 1663-1667. https://doi.org/10.1007/s00436-018-5857-z

Surveillance was conducted to investigate the occurrence of protozoan parasites of the genus Cryptosporidium in dogs newly admitted to a dog rehoming charity in London, Great Britain. Voided faecal samples were collected from all new admissions betwe... Read More about The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk?.

What has changed in canine pyoderma? A narrative review (2018)
Journal Article
Loeffler, A., & Lloyd, D. H. (2018). What has changed in canine pyoderma? A narrative review. https://doi.org/10.1016/j.tvjl.2018.04.002

Canine pyoderma is a common presentation in small animal practice and frequently leads to prescription of systemic antimicrobial agents. A good foundation of knowledge on pyoderma was established during the 1970s and 1980s, when treatment of infectio... Read More about What has changed in canine pyoderma? A narrative review.

Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life (2018)
Journal Article
Van Hoek, I., Payne, J. R., Feugier, A., & Connolly, D. J. (2018). Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life. https://doi.org/10.1016/j.vas.2018.03.002

Abstract A high degree of accuracy is required when using echocardiography to diagnose hypertrophic cardiomyopathy (HCM) in cats, as variation in measurements of 0.5 mm may affect classification of individuals as ‘abnormal’. This study in adult cats... Read More about Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life.

A physical model suggests that hip-localized balance sense in birds improves state estimation in perching: implications for bipedal robots (2018)
Journal Article
Urbina-Meléndez, D., Jalaleddini, K., Daley, M. A., & Valero-Cuevas, F. J. (2018). A physical model suggests that hip-localized balance sense in birds improves state estimation in perching: implications for bipedal robots. Frontiers in Robotics and AI, 5(38), https://doi.org/10.3389/frobt.2018.00038

In addition to a vestibular system, birds uniquely have a balance-sensing organ within the pelvis, called the lumbosacral organ (LSO). The LSO is well developed in terrestrial birds, possibly to facilitate balance control in perching and terrestrial... Read More about A physical model suggests that hip-localized balance sense in birds improves state estimation in perching: implications for bipedal robots.

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni (2018)
Journal Article
Viana, M., Faust, C. L., Haydon, D. T., Webster, J. P., & Lamberton, P. H. L. (2018). The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni. Evolutionary Applications, 11(3), 488-500. https://doi.org/10.1111/eva.12558

Natural selection acts on all organisms, including parasites, to maximize reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment. Schistosomiasis control programmes rely on mass drug admi... Read More about The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni.

25-Hydroxy vitamin D3 serum concentration in dogs with acute polyradiculoneuritis compared to matched controls (2018)
Journal Article
Laws, E. J., Kathrani, A., Harcourt-Brown, T. R., Granger, N., & Rose, J. H. (2018). 25-Hydroxy vitamin D3 serum concentration in dogs with acute polyradiculoneuritis compared to matched controls. Journal of Small Animal Practice, 59(4), 222-227. https://doi.org/10.1111/jsap.12791

Objectives To determine if dogs with acute polyradiculoneuritis have lower serum 25-hydroxy vitamin D3 concentration compared to a control group of dogs with idiopathic epilepsy. Materials and Methods Retrospective case–control study of 21 dogs... Read More about 25-Hydroxy vitamin D3 serum concentration in dogs with acute polyradiculoneuritis compared to matched controls.

Sperm preparation through Sephadex™ filtration improves in vitro fertilization rate of buffalo oocytes (2018)
Journal Article
Husna, A. U., Azam, A., Qadeer, S., Awan, M. A., Nasreen, S., Shahzad, Q., …Akhter, S. (2018). Sperm preparation through Sephadex™ filtration improves in vitro fertilization rate of buffalo oocytes. Reproduction in Domestic Animals, 53(2), 377-384. https://doi.org/10.1111/rda.13117

Routinely, swim-up method is used to separate high-quality sperm; however, long processing time and close cell-to-cell contact during the centrifugation step are inevitable elements of oxidative stress to sperm. The objective was to evaluate Sephadex... Read More about Sperm preparation through Sephadex™ filtration improves in vitro fertilization rate of buffalo oocytes.

Pericardial effusion associated with systemic inflammatory disease in seven dogs (January 2006 – January 2012) (2018)
Journal Article
Covey, H. L., & Connolly, D. J. (2018). Pericardial effusion associated with systemic inflammatory disease in seven dogs (January 2006 – January 2012). Journal of Veterinary Cardiology, 20(2), 123-128. https://doi.org/10.1016/j.jvc.2017.11.002

Pericardial effusion (PE) is reported in dogs as a consequence of neoplasia, primary cardiac disease or as an idiopathic condition. We describe seven dogs with systemic inflammatory disease, PE without tamponade and increased cardiac troponin I conce... Read More about Pericardial effusion associated with systemic inflammatory disease in seven dogs (January 2006 – January 2012).

Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms (2018)
Journal Article
Patel, J. J., Zhu, D., Opdebeeck, B., D'Haese, P., Millán, J. L., Bourne, L. E., …Orriss, I. R. (2018). Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms. Journal of Cellular Physiology, 233(4), 3230-3243. https://doi.org/10.1002/jcp.26166

Arterial medial calcification (AMC) is thought to share some outward similarities to skeletal mineralization and has been associated with the transdifferentiation of vascular smooth muscle cells (VSMCs) to an osteoblast‐like phenotype. ATP and UTP ha... Read More about Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms.

Trade patterns facilitating highly pathogenic avian influenza virus dissemination in the free-grazing layer duck system in Vietnam (2018)
Journal Article
Meyer, A., Dinh, T. X., Han, T. A., Do, D. V., Nhu, T. V., Pham, L. T., …Vergne, T. (2018). Trade patterns facilitating highly pathogenic avian influenza virus dissemination in the free-grazing layer duck system in Vietnam. Transboundary and Emerging Diseases, 65(2), 408-419. https://doi.org/10.1111/tbed.12697

Highly pathogenic avian influenza (HPAI) viruses continue to threaten smallholder poultry producers in several South‐east Asian countries, including Vietnam. In particular, the free‐grazing duck system has been repeatedly highlighted as a major risk... Read More about Trade patterns facilitating highly pathogenic avian influenza virus dissemination in the free-grazing layer duck system in Vietnam.

Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa (2018)
Journal Article
Borlase, A., Webster, J. P., & Rudge, J. W. (2018). Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa. Evolutionary Applications, 11(4), 501-515. https://doi.org/10.1111/eva.12529

Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control. Evidence for hybridizations and introgressions... Read More about Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa.

Nourishing dogs and cats through their twilight years (2018)
Journal Article
Lumbis, R. H. (2018). Nourishing dogs and cats through their twilight years. Veterinary Nurse, 9(2), 75-82

Ageing dogs and cats represent a significant proportion of the canine and feline population. Factors attributed to increasing longevity in these species include improved veterinary health care; nutrition; and a healthier lifestyle. Lifespan is also r... Read More about Nourishing dogs and cats through their twilight years.

Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9 (2018)
Journal Article
Koo, T., Lu-Nguyen, N. B., Malerba, A., Kim, E., Kim, D., Cappellari, O., …Kim, J. (2018). Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9. Molecular Therapy, https://doi.org/10.1016/j.ymthe.2018.03.018

Duchenne muscular dystrophy (DMD) is a fatal, X-linked muscle wasting disease caused by mutations in the DMD gene. In 51% of DMD cases, a reading frame is disrupted because of deletion of several exons. Here, we show that CjCas9 derived from Campylob... Read More about Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9.

Clinical presentation and magnetic resonance imaging findings in 11 dogs with eosinophilic meningoencephalitis of unknown aetiology (2018)
Journal Article
Cardy, T. J. A., & Cornelius, I. (2018). Clinical presentation and magnetic resonance imaging findings in 11 dogs with eosinophilic meningoencephalitis of unknown aetiology. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.12837

Eleven dogs were included with a median age of 22·0 months (range 7·6 to 92·0 months). Nine breeds were represented. Neurological abnormalities included obtundation (n=10), menace response deficits (n=9), proprioceptive deficits (n=7), ataxia (n=7) a... Read More about Clinical presentation and magnetic resonance imaging findings in 11 dogs with eosinophilic meningoencephalitis of unknown aetiology.