E J Laws
25-Hydroxy vitamin D3 serum concentration in dogs with acute polyradiculoneuritis compared to matched controls
Laws, E J; Kathrani, A; Harcourt-Brown, T R; Granger, N; Rose, J H
Authors
A Kathrani
T R Harcourt-Brown
N Granger
J H Rose
Abstract
Objectives
To determine if dogs with acute polyradiculoneuritis have lower serum 25-hydroxy vitamin D3 concentration compared to a control group of dogs with idiopathic epilepsy.
Materials and Methods
Retrospective case–control study of 21 dogs with acute canine polyradiculoneuritis and 21 control dogs with idiopathic epilepsy matched for year and season of presentation from a referral hospital population in the UK. Serum concentration of 25-hydroxy vitamin D3 was compared between groups using Student's t-test.
Results
Dogs with acute canine polyradiculoneuritis had significantly lower (P=0·033) serum 25-hydroxy vitamin D3 concentration (87·1?nmol/L ±55·4?nmol/L) compared to a control group with idiopathic epilepsy (113?nmol/L ±66·3?nmol/L).
Clinical Significance
The cause and clinical significance of the altered vitamin D status in dogs with acute polyradiculoneuritis are not clear and require further investigation. Our findings pave the way for improved understanding of acute canine polyradiculoneuritis and, potentially, improved clinical management, if a causal role for 25-hydroxy vitamin D3 is defined
Citation
Laws, E. J., Kathrani, A., Harcourt-Brown, T. R., Granger, N., & Rose, J. H. (2018). 25-Hydroxy vitamin D3 serum concentration in dogs with acute polyradiculoneuritis compared to matched controls. Journal of Small Animal Practice, 59(4), 222-227. https://doi.org/10.1111/jsap.12791
Journal Article Type | Article |
---|---|
Publication Date | Apr 1, 2018 |
Deposit Date | Dec 15, 2017 |
Journal | JOURNAL OF SMALL ANIMAL PRACTICE |
Print ISSN | 0022-4510 |
Electronic ISSN | 1748-5827 |
Publisher | Wiley |
Volume | 59 |
Issue | 4 |
Pages | 222-227 |
DOI | https://doi.org/10.1111/jsap.12791 |
Public URL | https://rvc-repository.worktribe.com/output/1387856 |
Downloadable Citations
About RVC Repository
Administrator e-mail: publicationsrepos@rvc.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search