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Time lapse: A glimpse into prehistoric genomics (2019)
Journal Article
Griffin, D. K., Larkin, D. M., & O'Connor, R. E. (2019). Time lapse: A glimpse into prehistoric genomics. European Journal of Medical Genetics, https://doi.org/10.1016/j.ejmg.2019.03.004

For the purpose of this review, ‘time-lapse’ refers to the reconstruction of ancestral (in this case dinosaur) karyotypes using genome assemblies of extant species. Such reconstructions are only usually possible when genomes are assembled to ‘chromos... Read More about Time lapse: A glimpse into prehistoric genomics.

Functional Electrical Stimulation following nerve injury in a Large Animal Model (2019)
Journal Article
Cercone, M., Jarvis, J., Ducharme, N., Perkins, J. D. M., Piercy, R. J., Willand, M., …Cheetham, J. (2019). Functional Electrical Stimulation following nerve injury in a Large Animal Model. Muscle & Nerve, 59(6), 717-725. https://doi.org/10.1002/mus.26460

Introduction: Controversy exists over the effects of functional electrical stimulation (FES) on reinnervation. We hypothesized that intramuscular FES would not delay reinnervation after recurrent laryngeal nerve (RLn) axonotmesis. Methods: RLn cryo‐i... Read More about Functional Electrical Stimulation following nerve injury in a Large Animal Model.

Vascular white matter lesions negatively correlate with brain metastases in malignant melanoma - results from a retrospective comparative analysis (2019)
Journal Article
Berk, B. A., Hering, K., Kortmann, R., Hoffmann, K., Ziemer, M., & Seidel, C. (2019). Vascular white matter lesions negatively correlate with brain metastases in malignant melanoma - results from a retrospective comparative analysis. Clinical Neurology and Neurosurgery, 180, 117-121. https://doi.org/10.1016/j.clineuro.2019.03.016

Brain metastasis (BM) is a major complication of different cancers. There is increasing evidence for influence of vascular factors on BM in patients with non-small cell lung cancer (NSCLC). It is not known if the same is true for other tumors that mi... Read More about Vascular white matter lesions negatively correlate with brain metastases in malignant melanoma - results from a retrospective comparative analysis.

Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations (2019)
Journal Article
Igoshin, A. V., Yurchenko, A. A., Belonogova, N. M., Petrovsky, D. V., Aitnazarov, R. B., Soloshenko, V. A., …Larkin, D. M. (2019). Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations. BMC Genomics, 20(Suppl 1), https://doi.org/10.1186/s12863-019-0725-0

Design of new highly productive livestock breeds, well-adapted to local climatic conditions is one of the aims of modern agriculture and breeding. The genetics underlying economically important traits in cattle are widely studied, whereas our knowled... Read More about Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations.

Fate of CMY-2-encoding plasmids introduced into the human fecal microbiota by exogenous Escherichia coli (2019)
Journal Article
Anjum, M., Madsen, J. S., Nesme, J., Jana, B., Wiese, M., Jasinskyte, D., …Guardabassi, L. (2019). Fate of CMY-2-encoding plasmids introduced into the human fecal microbiota by exogenous Escherichia coli. Antimicrobial Agents and Chemotherapy, 63(5), https://doi.org/10.1128/AAC.02528-18

The gut is a hot spot for transfer of antibiotic resistance genes from ingested exogenous bacteria to the indigenous microbiota. The objective of this study was to determine the fate of two nearly identical blaCMY-2-harboring plasmids introduced into... Read More about Fate of CMY-2-encoding plasmids introduced into the human fecal microbiota by exogenous Escherichia coli.

Species identity dominates over environment in shaping the microbiota of small mammals (2019)
Journal Article
Knowles, S. C. L., Eccles, R. M., & Baltrunaite, L. (2019). Species identity dominates over environment in shaping the microbiota of small mammals. Ecology Letters, 22(5), 826-837. https://doi.org/10.1111/ele.13240

The mammalian gut microbiota is considered pivotal to host fitness, yet the determinants of community composition remain poorly understood. Laboratory studies show that environmental factors, particularly diet, are important, while comparative work e... Read More about Species identity dominates over environment in shaping the microbiota of small mammals.

Survey of surgical specialists’ content preferences in radiology reports for extrahepatic portosystemic shunts (2019)
Journal Article
Plested, M. J., & Drees, R. (2019). Survey of surgical specialists’ content preferences in radiology reports for extrahepatic portosystemic shunts. https://doi.org/10.1111/vru.12730

The aim of this prospective, survey study was to assess the opinions of specialist surgeons as to the preferred content, nomenclature, and classification of extrahepatic portosystemic shunts for inclusion in radiology reports. A link to an online sur... Read More about Survey of surgical specialists’ content preferences in radiology reports for extrahepatic portosystemic shunts.

The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan (2019)
Journal Article
Neves, M. I., Malkawi, I., Walker, M., Alaboudi, A., Abu-Basha, E., Blake, D. P., …Crotta, M. (2019). The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan. Epidemiology and Infection, 147, E134. https://doi.org/10.1017/S0950268818003308

Campylobacter is the leading cause of foodborne bacterial gastroenteritis in humans worldwide, often associated with the consumption of undercooked poultry. In Jordan, the majority of broiler chicken production occurs in semi-commercial farms, where... Read More about The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan.

Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation (2019)
Journal Article
Mahmoud, M., Evans, I. M., Mehta, V., Pellet-Many, C., Paliashvili, K., & Zachary, I. (2019). Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation. https://doi.org/10.1152/ajpcell.00405.2018

Neuropilin 1 (NRP1) is important for neuronal and cardiovascular development due to its role in conveying class 3 semaphorin and vascular endothelial growth factor signaling, respectively. NRP1 is expressed in smooth muscle cells (SMCs) and mediates... Read More about Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation.

Relating neuromuscular control to functional anatomy of limb muscles in extant archosaurs (2019)
Journal Article
Cuff, A. R., Daley, M. A., Michel, K. B., Allen, V. R., Lamas, L. P., Adami, C., …Hutchinson, J. R. (2019). Relating neuromuscular control to functional anatomy of limb muscles in extant archosaurs. Journal of Morphology, 280(5), 666-680. https://doi.org/10.1002/jmor.20973

Electromyography (EMG) is used to understand muscle activity patterns in animals. Understanding how much variation exists in muscle activity patterns in homologous muscles across animal clades during similar behaviours is important for evaluating the... Read More about Relating neuromuscular control to functional anatomy of limb muscles in extant archosaurs.

Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice (2019)
Journal Article
Reade, S., Williams, J. M., Aggio, R., Duckworth, C. A., Mahalhal, A., Hough, R., …Probert, C. S. (2019). Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice. FASEB Journal, 33(3), 3129-3136. https://doi.org/10.1096/fj.201800076RR

Metabolomics studies have the potential to discover biomarkers. Fecal volatile organic compounds (VOCs) have been found to differ in patients with inflammatory bowel disease and irritable bowel syndrome. Murine models of colitis offer an alternative... Read More about Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice.

What are Employers Looking for in New Veterinary Graduates? A Content Analysis of UK Veterinary Job Advertisements (2019)
Journal Article
Perrin, H. C. (2019). What are Employers Looking for in New Veterinary Graduates? A Content Analysis of UK Veterinary Job Advertisements. Journal of Veterinary Medical Education, 46(1), 21-27. https://doi.org/10.3138/jvme.0317-045r

As veterinary educators, we have a responsibility to ensure that our graduates are prepared for working life. Veterinary practices, like any other businesses, rely on good employees, and the implications of a poor match between newly employed veterin... Read More about What are Employers Looking for in New Veterinary Graduates? A Content Analysis of UK Veterinary Job Advertisements.

From the raw bar to the bench: Bivalves as models for human health (2019)
Journal Article
Fernández Robledo, J. A., Yadavalli, R., Allam, B., Pales Espinosa, E., Gerdol, M., Greco, S., …Metzger, M. J. (2019). From the raw bar to the bench: Bivalves as models for human health. Developmental and Comparative Immunology, 92, 260-282. https://doi.org/10.1016/j.dci.2018.11.020

Bivalves, from raw oysters to steamed clams, are popular choices among seafood lovers and once limited to the coastal areas. The rapid growth of the aquaculture industry and improvement in the preservation and transport of seafood have enabled them t... Read More about From the raw bar to the bench: Bivalves as models for human health.

Use of atracurium and its reversal with neostigmine in 14 pet rabbits undergoing ophthalmic surgery: a retrospective study (2019)
Journal Article
Adami, C., Sanchez, R. F., & Monticelli, P. (2019). Use of atracurium and its reversal with neostigmine in 14 pet rabbits undergoing ophthalmic surgery: a retrospective study. Veterinary Record, 184(14), https://doi.org/10.1136/vr.105266

The objective of this retrospective study was to report the clinical use of atracurium and its reversal with neostigmine in pet rabbits. The medical records of 14 rabbits undergoing anaesthesia for ophthalmic surgery were located through a search of... Read More about Use of atracurium and its reversal with neostigmine in 14 pet rabbits undergoing ophthalmic surgery: a retrospective study.

CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment (2019)
Journal Article
Tirella, A., Kloc-Muniak, K., Good, L., Ridden, J., Ashford, M., Puri, S., & Tirelli, N. (2019). CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment. International Journal of Pharmaceutics, 561, 114-123. https://doi.org/10.1016/j.ijpharm.2019.02.032

KRAS is a small GTPase that regulates cell proliferation and survival. In tumors, the KRAS gene is mutated, and leading to unregulated tumor growth. Despite the recognized importance of KRAS in cancer, attempts to develop small molecule inhibitors ha... Read More about CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment.

Comparison of the diagnostic value of symmetric dimethylarginine, cystatin C, and creatinine for detection of decreased glomerular filtration rate in dogs (2019)
Journal Article
Pelander, L., Häggström, J., Larsson, A., Syme, H. M., Elliott, J., Heiene, R., & Ljungvall, I. (2019). Comparison of the diagnostic value of symmetric dimethylarginine, cystatin C, and creatinine for detection of decreased glomerular filtration rate in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15445

Mycobacterium avium paratuberculosis infection of calves – The impact of dam infection status (2019)
Journal Article
Patterson, S., Bond, K., Green, M., Van Winden, S. C. L., & Guitian, J. (2019). Mycobacterium avium paratuberculosis infection of calves – The impact of dam infection status. Preventive Veterinary Medicine, https://doi.org/10.1016/j.prevetmed.2019.02.009

Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic condition of dairy cattle, and is endemic in the UK. Lack of understanding of the relative importance of different transmission routes reduces the impact of co... Read More about Mycobacterium avium paratuberculosis infection of calves – The impact of dam infection status.

Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results (2019)
Journal Article
Hughes, J. R., Szladovits, B., & Drees, R. (2019). Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results. https://doi.org/10.1111/vru.12717

Canine mast cell tumor staging is commonly performed using abdominal ultrasonography and fine‐needle aspiration cytology of masses, lymph nodes, and hepatic and splenic parenchyma. Computed tomography is used for abdominal, thoracic, or whole body im... Read More about Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results.