A V Igoshin
Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations
Igoshin, A V; Yurchenko, A A; Belonogova, N M; Petrovsky, D V; Aitnazarov, R B; Soloshenko, V A; Yudin, N S; Larkin, D M
Authors
A A Yurchenko
N M Belonogova
D V Petrovsky
R B Aitnazarov
V A Soloshenko
N S Yudin
D M Larkin
Abstract
Design of new highly productive livestock breeds, well-adapted to local climatic conditions is one of the aims of modern agriculture and breeding. The genetics underlying economically important traits in cattle are widely studied, whereas our knowledge of the genetic mechanisms of adaptation to local environments is still scarce. To address this issue for cold climates we used an integrated approach for detecting genomic intervals related to body temperature maintenance under acute cold stress. Our approach combined genome-wide association studies (GWAS) and scans for signatures of selection applied to a cattle population (Hereford and Kazakh Whiteheaded beef breeds) bred in Siberia. We utilized the GGP HD150K DNA chip containing 139,376 single nucleotide polymorphism markers.
Citation
Igoshin, A. V., Yurchenko, A. A., Belonogova, N. M., Petrovsky, D. V., Aitnazarov, R. B., Soloshenko, V. A., Yudin, N. S., & Larkin, D. M. (2019). Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations. BMC Genomics, 20(Suppl 1), https://doi.org/10.1186/s12863-019-0725-0
Journal Article Type | Article |
---|---|
Acceptance Date | Mar 12, 2019 |
Publication Date | Mar 18, 2019 |
Deposit Date | Mar 14, 2019 |
Publicly Available Date | Mar 14, 2019 |
Journal | BMC Genomics |
Electronic ISSN | 1471-2164 |
Publisher | BioMed Central |
Peer Reviewed | Peer Reviewed |
Volume | 20 |
Issue | Suppl 1 |
DOI | https://doi.org/10.1186/s12863-019-0725-0 |
Public URL | https://rvc-repository.worktribe.com/output/1383136 |
Files
11978.pdf
(1 Mb)
PDF
You might also like
Dinosaurs: Comparative Cytogenomics of Their Reptile Cousins and Avian Descendants
(2022)
Journal Article
Downloadable Citations
About RVC Repository
Administrator e-mail: publicationsrepos@rvc.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2025
Advanced Search