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All Outputs (506)

Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects (2021)
Journal Article
Tam, W. L., Freitas Mendes, L., Chen, X., Lesage, R., Van Hoven, I., Leysen, E., …Luyten, F. P. (2021). Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects. Stem Cell Research and Therapy, 12(1), https://doi.org/10.1186/s13287-021-02580-7

Background Bones have a remarkable capacity to heal upon fracture. Yet, in large defects or compromised conditions healing processes become impaired, resulting in delayed or non-union. Current therapeutic approaches often utilize autologous or allog... Read More about Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects.

Financial impact of sheeppox and goatpox and estimated profitability of vaccination for subsistence farmers in selected northern states of Nigeria (2021)
Journal Article
Rawlins, M., Limon, G., Adedeji, A., Ijoma, S., Atai, R., Adole, J., …Alarcon, P. (2022). Financial impact of sheeppox and goatpox and estimated profitability of vaccination for subsistence farmers in selected northern states of Nigeria. Preventative Veterinary Medicine, 198, https://doi.org/10.1016/j.prevetmed.2021.105503

Sheeppox and goatpox (SGP) are important transboundary diseases, endemic in Nigeria, causing severe clinical manifestations, impacting production, and resulting in economic losses. Vaccination is an effective control measure against SGP in endemic co... Read More about Financial impact of sheeppox and goatpox and estimated profitability of vaccination for subsistence farmers in selected northern states of Nigeria.

Challenges and solutions for diabetes early career researchers in the COVID-19 recovery – perspectives of the Diabetes UK Innovators in Diabetes (2021)
Journal Article
Gage, M. (in press). Challenges and solutions for diabetes early career researchers in the COVID-19 recovery – perspectives of the Diabetes UK Innovators in Diabetes. Diabetic Medicine, https://doi.org/10.1111/dme.14698

The COVID-19 pandemic has put diabetes at the forefront of conversation. The prevalence of type 2 diabetes in the UK is high1 and has links to adverse COVID-19 outcomes2. Research investigating the links between these two public health issues are mov... Read More about Challenges and solutions for diabetes early career researchers in the COVID-19 recovery – perspectives of the Diabetes UK Innovators in Diabetes.

The critical dynamic role of the tail in bipedal dinosaur locomotion (2021)
Journal Article
Bishop, P., Falisse, A., De Groote, F., & Hutchinson, J. (2021). The critical dynamic role of the tail in bipedal dinosaur locomotion. Science Advances, https://doi.org/10.1126/sciadv.abi7348

Locomotion has influenced the ecology, evolution, and extinction of species throughout history, yet studying locomotion in the fossil record is challenging. Computational biomechanics can provide novel insight by mechanistically relating observed ana... Read More about The critical dynamic role of the tail in bipedal dinosaur locomotion.

Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom (2021)
Journal Article
Glanemann, B., Tayler, S., Sparrow, R., Skelly, B., Swann, J., & Hall, H. (2021). Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom. PLoS ONE, https://doi.org/10.1371/journal.pone.0257700

Objectives: To determine whether veterinarians in PCPs and BCCs approach treatment of dogs with IMHA similarly, and whether practitioners with more experience treat similarly to those with less experience. We hypothesised those in PCPs would show mo... Read More about Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom.

S1P in the development of atherosclerosis: roles of haemodynamic wall shear stress and endothelial permeability (2021)
Journal Article
Warboys, C. M., & Weinberg, P. D. (2021). S1P in the development of atherosclerosis: roles of haemodynamic wall shear stress and endothelial permeability. Tissue Barriers, https://doi.org/10.1080/21688370.2021.1959243

Atherosclerosis is characterised by focal accumulations of lipid within the arterial wall, thought to arise from effects of haemodynamic wall shear stress (WSS) on endothelial permeability. Identifying pathways that mediate effects of shear on permea... Read More about S1P in the development of atherosclerosis: roles of haemodynamic wall shear stress and endothelial permeability.

Epidemiology of bovine brucellosis in Hisar, India: identification of risk factors and assessment of knowledge, attitudes, and practices among livestock owners (2021)
Journal Article
Saidu, A. S., Mahajan, N. K., Musallam, I. I., Holt, H. R., & Guitian, J. (2021). Epidemiology of bovine brucellosis in Hisar, India: identification of risk factors and assessment of knowledge, attitudes, and practices among livestock owners. Tropical Animal Health and Production, 53(5), https://doi.org/10.1007/s11250-021-02884-z

Antimicrobial Resistance Patterns and Risk Factors Associated with Salmonella spp. Isolates from Poultry Farms in the East Coast of Peninsular Malaysia: A Cross-Sectional Study (2021)
Journal Article
Osman, A. Y., Elmi, S. A., Simons, D., Elton, L., Haider, N., Khan, M. A., …Kock, R. (in press). Antimicrobial Resistance Patterns and Risk Factors Associated with Salmonella spp. Isolates from Poultry Farms in the East Coast of Peninsular Malaysia: A Cross-Sectional Study. Pathogens, 10(9), 1160. https://doi.org/10.3390/pathogens10091160

The burden of antimicrobial use in agricultural settings is one of the greatest challenges facing global health and food security in the modern era. Malaysian poultry operations are a relevant but understudied component of epidemiology of antimicro... Read More about Antimicrobial Resistance Patterns and Risk Factors Associated with Salmonella spp. Isolates from Poultry Farms in the East Coast of Peninsular Malaysia: A Cross-Sectional Study.

Surveillance of equine strangles in the United Kingdom between 2015 and 2019 based on laboratory detection of Streptococcus equi (2021)
Journal Article
Mcglennon, A., Waller, A., Verheyen, K., Slater, J., Grewar, J., & Newton, R. (in press). Surveillance of equine strangles in the United Kingdom between 2015 and 2019 based on laboratory detection of Streptococcus equi. Veterinary Record, https://doi.org/10.1002/vetr.948

Background: Previously national surveillance data for monitoring strangles (Streptococcus equi infection) in UK horses was limited. Improved awareness and knowledge of positive diagnoses would permit the optimisation of biosecurity protocols, decreas... Read More about Surveillance of equine strangles in the United Kingdom between 2015 and 2019 based on laboratory detection of Streptococcus equi.

CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4 (2021)
Journal Article
Marr, N., Meeson, R., Kelly, E., Fang, Y., Peffers, M., Pitsillides, A., …Thorpe, C. (2021). CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4. International Journal of Molecular Sciences, https://doi.org/10.3390/ijms22189729

The interfascicular matrix (IFM) binds tendon fascicles and contains a population of morphologically distinct cells; however the role of IFM-localised cell populations in tendon repair remains to be determined. The basement membrane protein laminin-α... Read More about CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4.

N-acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: the role of L-cysteine and hydrogen sulphide (2021)
Journal Article
Orriss, I., Bourne, L. E., Patel, J. J., Davies, B. K., Neven, E., Verhulst, A., …Orriss, I. R. (in press). N-acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: the role of L-cysteine and hydrogen sulphide. Journal of Cellular Physiology, https://doi.org/10.1002/jcp.30605

Arterial medial calcification (AMC) is the deposition of calcium phosphate in the arteries. AMC is widely thought to share similarities with physiological bone formation; however, emerging evidence suggests several key differences between these proce... Read More about N-acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: the role of L-cysteine and hydrogen sulphide.

Ear infections in dogs [Infographic] (2021)
Other
O'Neill, D., Volk, A., Soares, T., Church, D., Brodbelt, D., & Pegram, C. (2021). Ear infections in dogs [Infographic]. [Infographic]

The Emergence and Zoonotic Transmission of H10Nx Avian Influenza Virus Infections (2021)
Journal Article
Everest, H., Billington, E., Daines, R., Burman, A., & Iqbal, M. (2021). The Emergence and Zoonotic Transmission of H10Nx Avian Influenza Virus Infections. mBio, 12(5), https://doi.org/10.1128/mBio.01785-21

Avian influenza viruses pose a continuous threat to both poultry and human health, with significant economic impact. The ability of viruses to reassort and jump the species barrier into mammalian hosts generates a constant pandemic threat. H10Nx avia... Read More about The Emergence and Zoonotic Transmission of H10Nx Avian Influenza Virus Infections.

Cross sectional study to identify prevalence of and factors associated with laminitis in UK donkeys (2021)
Journal Article
Menzies‐Gow, N., Wakeel, F., Little, H., Buil, J., & Rickards, K. (in press). Cross sectional study to identify prevalence of and factors associated with laminitis in UK donkeys. Journal of Equine Veterinary Science, https://doi.org/10.1111/evj.13505

Background Laminitis causes lameness in donkeys, but its prevalence and factors associated with disease remain uncertain. Objectives To determine the prevalence of and identify factors associated with laminitis in donkeys. Study design Retro... Read More about Cross sectional study to identify prevalence of and factors associated with laminitis in UK donkeys.