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All Outputs (10)

Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs (2025)
Journal Article
Béguin, J., Mahfoudhi, S., Uzel, M., Rostang, A., Ibish, C., Ferran, A., Pelligand, L., Hulin, A., & Kohlhauer, M. (in press). Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs. BMC Veterinary Research, https://doi.org/10.1186/s12917-024-04404-1

Carboplatin is a human chemotherapeutic agent which is frequently used in dogs for the management of solid tumors. In human patient, its dosage is adjusted carefully, based on the creatinine clearance computation. In dogs however, the pharmacokinetic... Read More about Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs.

Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens (2025)
Journal Article
Mead, A., Hughes, A., Azzariti, S., Toutain, P.-L., & Pelligand, L. (2025). Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13500

This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae, and Pasteurella multocida. In vitro time-kill assays and... Read More about Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens.

Beagles kept as companion animals in the UK – demography, disorders and mortality (2025)
Journal Article
O'Neill, D., Schiksnis, M. R., Brodbelt, D. C., Church, D. B., Goldberg, S., & Engdahl, K. S. (2025). Beagles kept as companion animals in the UK – demography, disorders and mortality. Companion Animal Health and Genetics, 12(1), https://doi.org/10.1186/s40575-024-00140-9

Background Beagles are a popular companion animal dog breed and are generally stated to be a healthy breed.
This VetCompass study aimed to report the demography, common disorders and mortality of Beagles under primary
veterinary care in the UK. Ano... Read More about Beagles kept as companion animals in the UK – demography, disorders and mortality.

A new future for dog breeding (2025)
Journal Article
Proschowsky, H., Arendt, M., Bonnett, B., Bruun, C., Czycholl, I., Fredholm, M., O'Neill, D., Serpell, J., & Sandoe, P. (2025). A new future for dog breeding. Animal Welfare Journal, 34, https://doi.org/10.1017/awf.2024.66

The modern idea of purebred dogs has come under increasing critical scrutiny over recent decades. In light of this critical focus and other developments in society, some new trends in how companion dogs are bred and acquired have emerged. This means... Read More about A new future for dog breeding.

Early-life enrichment in American mink (Neogale vison): Effects of juvenile physical enrichment on behaviour, temperament, and long-term stereotypic behaviour (2025)
Journal Article
Clark, G., Díez-León, M., & Meagher, R. (2025). Early-life enrichment in American mink (Neogale vison): Effects of juvenile physical enrichment on behaviour, temperament, and long-term stereotypic behaviour. Animal Welfare Journal, 34, https://doi.org/10.1017/awf.2024.72

A single manipulable enrichment is often introduced to the pens of farmed American mink (Neogale vison) to combat stereotypic behaviour and behaviours or temperaments associated with poor welfare (e.g. inactivity, fear, and aggression). This enrichme... Read More about Early-life enrichment in American mink (Neogale vison): Effects of juvenile physical enrichment on behaviour, temperament, and long-term stereotypic behaviour.

Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses (2025)
Journal Article
Palomino Lago, E., Ross, A., McClellan, A., & Guest, D. (2025). Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses. Animal Genetics, https://doi.org/10.1111/age.13504

Bone fractures are a significant problem in Thoroughbred racehorses. The risk of fracture is influenced by both genetic and environmental factors. To determine the biological processes that are affected in genetically susceptible horses, we utilised... Read More about Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses.

Can biosecurity on farms reduce bovine tuberculosis risks in cattle in England? A review of observational and literature‐based evidence (2025)
Journal Article
Voller, C., Perrin, L. D., Gibbens, J. C., Donnelly, C. A., Delahay, R. J., Heasman, L., Vial, F., Prosser, A., Heard, J., Robertson, A., Brunton, L., Enticott, G., & Downs, S. H. (2025). Can biosecurity on farms reduce bovine tuberculosis risks in cattle in England? A review of observational and literature‐based evidence. Veterinary Record, 196(1), https://doi.org/10.1002/vetr.4912

Background
Bovine tuberculosis (TB) is a burden to cattle farming in Great Britain. Poor biosecurity has been identified as contributing to the epidemic.

Methods
We conducted a systematic review of epidemiological studies published in the scient... Read More about Can biosecurity on farms reduce bovine tuberculosis risks in cattle in England? A review of observational and literature‐based evidence.