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An examination of two different approaches for the study of femoral neck fracture: towards a more relevant rodent model (2021)
Journal Article
Monzem, S., Gohin, S., Yagüe Ballester, R., Lopes de Souza, R., Meeson, R., & Anthony Pitsillides, A. (2021). An examination of two different approaches for the study of femoral neck fracture: towards a more relevant rodent model. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, https://doi.org/10.1177/09544119211053057

Femoral neck fractures are a massive personal and health programme burden. Methods to study femoral neck strength, across its combined trabecular and cortical components are therefore essential. Rodent ovariectomy-induced osteoporosis models are comm... Read More about An examination of two different approaches for the study of femoral neck fracture: towards a more relevant rodent model.

Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone (2021)
Journal Article
Monzem, S., Javaheri, B., de Souza, R. L., & Pitsillides, A. A. (2021). Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone. Bone Reports, 101116. https://doi.org/10.1016/j.bonr.2021.101116

Disuse osteoporosis occurs after extended periods of bed rest or nerve damage leading to increased risk of fracture. It remains to be established, however, whether the trajectory of bone loss is equivalent in bone's cortical and trabecular compartmen... Read More about Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone.

The plate-to-rod transition in trabecular bone loss is elusive (2021)
Journal Article
Felder, A. A., Monzem, S., De Souza, R., Javaheri, B., Mills, D., Boyde, A., & Doube, M. (2021). The plate-to-rod transition in trabecular bone loss is elusive. Royal Society Open Science, 8(6), 201401. https://doi.org/10.1098/rsos.201401

Changes in trabecular micro-architecture are key to our understanding of osteoporosis. Previous work focusing on structure model index (SMI) measurements have concluded that disease progression entails a shift from plates to rods in trabecular bone,... Read More about The plate-to-rod transition in trabecular bone loss is elusive.