Skip to main content

Research Repository

Advanced Search

Outputs (423)

ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae (2016)
Journal Article
Bossé, J. T., Li, Y., Fernandez Crespo, R., Chaudhuri, R. R., Rogers, J., Holden, M. T., Maskell, D. J., Tucker, A. W., Wren, B. W., Rycroft, A. N., Langford, P. R., & BRaDP1T Consortium. (2016). ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae. Frontiers in Microbiology, 7, https://doi.org/10.3389/fmicb.2016.00810

Biomarkers of browning of white adipose tissue and their regulation during exercise- and diet-induced weight loss (2016)
Journal Article
Nakhuda, A., Josse, A. R., Gburcik, V., Crossland, H., Raymond, F., Metairon, S., Good, L., Atherton, P. J., Phillips, S. M., & Timmons, J. A. (2016). Biomarkers of browning of white adipose tissue and their regulation during exercise- and diet-induced weight loss. American Journal of Clinical Nutrition, 104(3), 557-565. https://doi.org/10.3945/ajcn.116.132563

Detection of Rare Antimicrobial Resistance Profiles by Active and Passive Surveillance Approaches (2016)
Journal Article
Mather, A., Reeve, R., Mellor, D. J., Matthews, L., Reid-Smith, R. J., Dutil, L., Haydon, D. T., & Reid, S. W. J. (2016). Detection of Rare Antimicrobial Resistance Profiles by Active and Passive Surveillance Approaches. PLoS ONE, 11(7), e0158515. https://doi.org/10.1371/journal.pone.0158515

Antimicrobial resistance (AMR) surveillance systems are generally not specifically designed to detect emerging resistances and usually focus primarily on resistance to individual drugs. Evaluating the diversity of resistance, using ecological metrics... Read More about Detection of Rare Antimicrobial Resistance Profiles by Active and Passive Surveillance Approaches.

The impact of albendazole treatment on the incidence of viral- and bacterial-induced diarrhea in school children in southern Vietnam: study protocol for a randomized controlled trial (2016)
Journal Article
Leung, J. M., Hong, C. T. T., Trung, N. H. D., Thi, H. N., Minh, C. N. N., Thi, T. V., Hong, D. T., Man, D. N. H., Knowles, S. C. L., Wolbers, M., Hoang, N. L. T., Thwaites, G., Graham, A. L., & Baker, S. (2016). The impact of albendazole treatment on the incidence of viral- and bacterial-induced diarrhea in school children in southern Vietnam: study protocol for a randomized controlled trial. Trials, 17(279), https://doi.org/10.1186/s13063-016-1406-1

Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries (2016)
Journal Article
Mbugi, E. V., Katale, B. Z., Streicher, E. M., Keyyu, J. D., Kendall, S. L., Dockrell, H. M., Michel, A. L., Rweyemamu, M. M., Warren, R. M., Matee, M. I., van Helden, P. D., Couvin, D., & Rastogi, N. (2016). Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries. PLoS ONE, 11(5), https://doi.org/10.1371/journal.pone.0154571

The global antigenic diversity of swine influenza A viruses (2016)
Journal Article
Lewis, N. S., Russell, C. A., Langat, P., Anderson, T. K., Berger, K., Bielejec, F., Burke, D. F., Dudas, G., Fonville, J. M., Fouchier, R. A., Kellam, P., Koel, B. F., Lemey, P., Nguyen, T., Nuansrichy, B., Peiris, J. M., Saito, T., Simon, G., Skepner, E., Takemae, N., …Vincent, A. L. (2016). The global antigenic diversity of swine influenza A viruses. eLife, 5, e12217. https://doi.org/10.7554/eLife.12217

wine influenza presents a substantial disease burden for pig populations worldwide and poses a potential pandemic threat to humans. There is considerable diversity in both H1 and H3 influenza viruses circulating in swine due to the frequent introduct... Read More about The global antigenic diversity of swine influenza A viruses.

The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis (2016)
Journal Article
Ho, N. A. T., Dawes, S. S., Crowe, A. M., Casabon, I., Gao, C., Kendall, S. L., Baker, E. N., Eltis, L. D., & Lott, J. S. (2016). The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. Journal of Biological Chemistry, 291(14), 7256-7266. https://doi.org/10.1074/jbc.M115.707760

Cholesterol can be a major carbon source for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma. KstR is a highly conserved TetR family transcriptional repressor tha... Read More about The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.

One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases (2016)
Journal Article
Webster, J. P., Gower, C. M., Knowles, S. C. L., & Fenton, A. (2016). One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases. Evolutionary Applications, 9(2), 313-333. https://doi.org/10.1111/eva.12341

Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most... Read More about One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases.

Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae (2016)
Journal Article
Bossé, J. T., Chaudhuri, R. R., Li, Y., Leanse, L. G., Fernandez Crespo, R., Coupland, P., Holden, M. T., Bazzoli, D. M., Maskell, D. J., Tucker, A. W., Wren, B. W., Rycroft, A. N., & Langford, P. R. (2016). Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae. Genome Announcements, 4(i), e01667-15. https://doi.org/10.1128/genomeA.01667-15

We report here the complete annotated genome sequence of a clinical serovar 8 isolate Actinobacillus pleuropneumoniae MIDG2331. Unlike the serovar 8 reference strain 405, MIDG2331 is amenable to genetic manipulation via natural transformation as well... Read More about Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae.

Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming (2016)
Journal Article
Easton, A. V., Oliveira, R. G., O'Connell, E. M., Kepha, S., Mwandawiro, C. S., Njenga, S. M., Kihara, J. H., Mwatele, C., Odiere, M. R., Brooker, S. J., Webster, J. P., Anderson, R. M., & Nutman, T. B. (2016). Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming. https://doi.org/10.1186/s13071-016-1314-y