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Outputs (423)

Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits (2021)
Journal Article
Kendall, S. L., Faulkner, V., Cox, A. A., Goh, S., van Bohemen, A., Gibson, A. J., Liebster, O., Wren, B. W., & Willcocks, S. (in press). Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits. Frontiers in Microbiology, 11, https://doi.org/10.3389/fmicb.2020.619427

A greater understanding of the genes involved in antibiotic resistance in Mycobacterium tuberculosis (Mtb) is necessary for the design of improved therapies. Clustered regularly interspaced short palindromic repeat interference (CRISPRi) has been pre... Read More about Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits.

A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves (2021)
Journal Article
Johnson, K. F., Chancellor, N., & Wathes, D. C. (in press). A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves. Animals, https://doi.org/10.3390/xxxxx

Simple Summary: Most dairy heifer calves are removed from their dam and reared on milk from birth until weaning at around nine weeks of age. During this period they are susceptible to diseases which reduce their welfare and later performance in the d... Read More about A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves.

Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America (2020)
Journal Article
Haider, N., Yavlinsky, A., Simons, D., Osman, A. Y., Ntoumi, F., Zumla, A., & Kock, R. A. (2020). Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America. Epidemiology and Infection, 148, https://doi.org/10.1017/S0950268820000424

Novel Coronavirus (2019-nCoV [SARS-COV-2]) was detected in humans during the last week of December 2019 at Wuhan city in China, and caused 24 554 cases in 27 countries and territories as of 5 February 2020. The objective of this study was to estimate... Read More about Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America.

Evaluation of potential risk of transmission of avian influenza A viruses at live bird markets in response to unusual crow die-offs in Bangladesh (2020)
Journal Article
Rahman, M., Mangtani, P., Uyeki, T. M., Cardwell, J. M., Torremorell, M., Islam, A., Samad, M. A., Muraduzzaman, A. K. M., Giasuddin, M., Sarkar, S., Alamgir, A. S. M., Salimuzzaman, M., & Flora, M. S. (2020). Evaluation of potential risk of transmission of avian influenza A viruses at live bird markets in response to unusual crow die-offs in Bangladesh. Influenza and Other Respiratory Viruses, https://doi.org/10.1111/irv.12716

In response to unusual crow die‐offs from avian influenza A(H5N1) virus infection during January‐February 2017 in Dhaka, Bangladesh, a One Health team assessed potential infection risks in live bird markets (LBMs). Evidence of aerosolized avian influ... Read More about Evaluation of potential risk of transmission of avian influenza A viruses at live bird markets in response to unusual crow die-offs in Bangladesh.

Outbreak of Peste des Petits Ruminants Virus among Criticially Endangered Mongolian Saiga and Other Wild Ungulates, Mongolia, 2016-2017 (2020)
Journal Article
Pruvot, M., Fine, A. E., Hollinger, C., Strindberg, S., Damdinjav, B., Buuveibaatar, B., Chimeddorj, B., Bayandonoi, G., Khishgee, B., Sandag, B., Narmandakh, J., Jargalsaikham, T., Bataa, B., McAloose, D., Shatar, M., Basan, G., Mahapatra, M., Selvaraj, M., Parida, S., Njeumi, F., …Shiilegdamba, E. (2020). Outbreak of Peste des Petits Ruminants Virus among Criticially Endangered Mongolian Saiga and Other Wild Ungulates, Mongolia, 2016-2017. https://doi.org/10.3201/eid2601.181998

The 2016–2017 introduction of peste des petits ruminants virus (PPRV) into livestock in Mongolia was followed by mass mortality of the critically endangered Mongolian saiga antelope and other rare wild ungulates. To assess the nature and population e... Read More about Outbreak of Peste des Petits Ruminants Virus among Criticially Endangered Mongolian Saiga and Other Wild Ungulates, Mongolia, 2016-2017.

Schistosomiasis — Assessing Progress toward the 2020 and 2025 Global Goals (2019)
Journal Article
Deol, A. K., Fleming, F. M., Calvo-Urbano, B., Walker, M., Bucumi, V., Gnandou, I., Tukahebwa, E. M., Jemu, S., Mwingira, U. J., Alkohlani, A., Traoré, M., Ruberanziza, E., Touré, S., Basáñez, M.-G., French, M. D., & Webster, J. P. (2019). Schistosomiasis — Assessing Progress toward the 2020 and 2025 Global Goals. New England Journal of Medicine, 381, 2519-2528. https://doi.org/10.1056/NEJMoa1812165

Modelling exposure heterogeneity and density dependence in onchocerciasis using a novel individual-based transmission model, EPIONCHO-IBM: implications for elimination and data needs (2019)
Journal Article
Hamley, J. I. D., Milton, P., Walker, M., & Basáñez, M.-G. (2019). Modelling exposure heterogeneity and density dependence in onchocerciasis using a novel individual-based transmission model, EPIONCHO-IBM: implications for elimination and data needs. PLoS Neglected Tropical Diseases, 13(12), https://doi.org/10.1371/journal.pntd.0007557

Exploring the Risk Posed by Animals with An Inconclusive Reaction to the Bovine Tuberculosis Skin Test in England and Wales (2019)
Journal Article
May, E., Prosser, A., Downs, S. H., & Brunton, L. A. (2019). Exploring the Risk Posed by Animals with An Inconclusive Reaction to the Bovine Tuberculosis Skin Test in England and Wales. Veterinary Sciences, 6(4), 97. https://doi.org/10.3390/vetsci6040097

The single intradermal comparative cervical tuberculin (SICCT) test is the primary test for ante-mortem diagnosis of bovine tuberculosis (TB) in England and Wales. When an animal is first classified as an inconclusive reactor (IR) using this test, it... Read More about Exploring the Risk Posed by Animals with An Inconclusive Reaction to the Bovine Tuberculosis Skin Test in England and Wales.

Life cycle stages, specific organelles and invasion mechanisms of Eimeria species (2019)
Journal Article
Burrell, A., Tomley, F. M., Vaughan, S., & Marugan-Hernandez, V. (2019). Life cycle stages, specific organelles and invasion mechanisms of Eimeria species. Parasitology, https://doi.org/10.1017/S0031182019001562

Apicomplexans, including species of Eimeria, pose a real threat to the health and wellbeing of animals and humans. Eimeria parasites do not infect humans but cause an important economic impact on livestock, in particular on the poultry industry. Desp... Read More about Life cycle stages, specific organelles and invasion mechanisms of Eimeria species.

Assessment on the adoption of recommended standards, novel approaches and best practices for animal health surveillance by decision makers in Europe (2019)
Journal Article
Haesler, B., Garza, M., Bisdorff, B., Leger, A., Tavornpanich, S., Peyre, M., Lindberg, A., Van Schaik, G., Alban, L., & Staerk, K. D. (2019). Assessment on the adoption of recommended standards, novel approaches and best practices for animal health surveillance by decision makers in Europe. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2019.00375

Animal health surveillance is an important tool for disease mitigation and helps to promote animal health and welfare, protect human health, support efficient animal production, and enable trade. This study aimed to assess adoption of recommended sta... Read More about Assessment on the adoption of recommended standards, novel approaches and best practices for animal health surveillance by decision makers in Europe.

Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission (2019)
Journal Article
Wood, C. L., Sokolow, S. H., Jones, I. J., Chamberlin, A. J., Lafferty, K. D., Kuris, A. M., Jocque, M., Hopkins, S., Adams, G., Buck, J. C., Lund, A. J., Garcia-vedreene, A. E., Fiorenza, E., Rohr, J. R., Allan, F., Webster, B., Rabone, M., Webster, J. P., Bandagny, L., Ndione, R., …De Leo, G. A. (2019). Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission. Proceedings of the National Academy of Sciences, 116(46), 23182-23191. https://doi.org/10.1073/pnas.1903698116

Recently, the World Health Organization recognized that efforts to interrupt schistosomiasis transmission through mass drug administration have been ineffective in some regions; one of their new recommended strategies for global schistosomiasis contr... Read More about Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission.

CD23 is a glycan-binding receptor in some mammalian species (2019)
Journal Article
Jégouzo, S. A. F., Feinberg, H., Morrison, A., Holder, A., May, A., Huang, Z., Jiang, L., Lasanajak, Y., Smith, D. F., Werling, D., Drickamer, K., Weis, W. I., & Taylor, M. E. (2019). CD23 is a glycan-binding receptor in some mammalian species. Journal of Biological Chemistry, https://doi.org/10.1074/jbc.RA119.010572

CD23, the low affinity IgE receptor found on B lymphocytes and other cells, contains a C-terminal lectin-like domain that resembles C-type carbohydrate-recognition domains (CRDs) found in many glycan-binding receptors. In most mammalian species, the... Read More about CD23 is a glycan-binding receptor in some mammalian species.

How should we store avian faecal samples for microbiota analyses? Comparing efficacy and cost-effectiveness (2019)
Journal Article
Vargas-Pellicer, P., Watrobska, C., Knowles, S. C. L., Schroeder, J., & Banks-Leite, C. (2019). How should we store avian faecal samples for microbiota analyses? Comparing efficacy and cost-effectiveness. Journal of Microbiological Methods, 165, https://doi.org/10.1016/j.mimet.2019.105689

Analyses of bacterial DNA in faecal samples are becoming ever more common, yet we still do not know much about bird microbiomes. These challenges partly lie in the unique chemical nature of their faeces, and in the choice of sample storage method, wh... Read More about How should we store avian faecal samples for microbiota analyses? Comparing efficacy and cost-effectiveness.

Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows (2019)
Journal Article
Tombacz, K., Peters, L. M., Chang, Y. M., Steele, M., Werling, D., & Gibson, A. J. (2019). Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows. Journal of Dairy Science, 102(10), 9389-9395. https://doi.org/10.3168/jds.2019-16563

In periparturient dairy cows, immune suppression, resulting in decreased neutrophil numbers and function, leads to increased susceptibility to postpartum conditions such as mastitis, retained placenta, and metritis. Administration of polyethylene gly... Read More about Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows.

Identifying hotspots for antibiotic resistance emergence and selection, and elucidating pathways to human exposure: Application of a systems-thinking approach to aquaculture systems (2019)
Journal Article
Brunton, L. A., Desbois, A. P., Garza, M., Wieland, B., Mohan, C. V., Haesler, B., Tam, C. C., Le, P. N. T., Phuong, N. T., Van, P. T., Nguyen-Viet, H., El Tholth, M., Pham, D. K., Duc, P. P., Linh, N. T., Rich, K. M., Mateus, A. L. P., Hoque, M. A., Ahad, A., Khan, M. N. A., …Guitian, J. (2019). Identifying hotspots for antibiotic resistance emergence and selection, and elucidating pathways to human exposure: Application of a systems-thinking approach to aquaculture systems. Science of the Total Environment, 687, 1344-1356. https://doi.org/10.1016/j.scitotenv.2019.06.134

Aquaculture systems are highly complex, dynamic and interconnected systems influenced by environmental, biological, cultural, socio-economic and human behavioural factors. Intensification of aquaculture production is likely to drive indiscriminate us... Read More about Identifying hotspots for antibiotic resistance emergence and selection, and elucidating pathways to human exposure: Application of a systems-thinking approach to aquaculture systems.

Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus (2019)
Journal Article
Dimitrov, K. M., Abolnik, C., Afonso, C. L., Albina, E., Bahl, J., Berg, M., Briand, F.-X., Brown, I. H., Choi, K.-S., Chvala, I., Diel, D. G., Durr, P. A., Ferreira, H. L., Fusaro, A., Gil, P., Goujgoulova, G. V., Grund, C., Hicks, J. T., Joannis, T. M., Torchetti, M. K., …Wong, F. Y. K. (2019). Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus. https://doi.org/10.1016/j.meegid.2019.103917

Mass Die-Off of Saiga Antelopes, Kazakhstan, 2015 (2019)
Journal Article
Fereidouni, S., Freimanis, G. L., Orynbayev, M., Ribeca, P., Flannery, J., King, D. P., Zuther, S., Beer, M., Höper, D., Kydyrmanov, A., Karamendin, K., & Kock, R. A. (2019). Mass Die-Off of Saiga Antelopes, Kazakhstan, 2015. https://doi.org/10.3201/eid2506.180990

In 2015, a mass die-off of ≈200,000 saiga antelope in central Kazakhstan was caused by hemorrhagic septicemia attributable to the bacterium Pasteurella multocida serotype B. Previous analyses have indicated that environmental triggers associated with... Read More about Mass Die-Off of Saiga Antelopes, Kazakhstan, 2015.

Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence (2019)
Journal Article
García-Sánchez, M., Jiménez-Pelayo, L., Horcajo, P., Regidor-Cerrillo, J., Ólafsson, E. B., Bhandage, A. K., Barragan, A., Werling, D., Ortega-Mora, L. M., & Collantes-Fernández, E. (2019). Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence. Frontiers in Immunology, 10(915), https://doi.org/10.3389/fimmu.2019.00915

Neospora caninum, a protozoan parasite closely related to Toxoplasma gondii, represents one of the main causes of abortion in cattle. Macrophages (MØs) are mediators of the innate immune response against infection and likely one of the first cells en... Read More about Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence.