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Outputs (423)

Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner (2017)
Journal Article
Schroeder, H., McCarthy, D., Szestak, T., Cook, D. A., Taylor, M., Craig, A. G., Lawson, C., & Lawrence, R. A. (2017). Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner. PLoS Neglected Tropical Diseases, 11(5), e0005592. https://doi.org/10.1371/journal.pntd.0005592

Brugia malayi causes the human tropical disease, lymphatic filariasis. Microfilariae (Mf) of this nematode live in the bloodstream and are ingested by a feeding mosquito vector. Interestingly, in a remarkable co-evolutionary adaptation, Mf appearance... Read More about Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.

Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics (2017)
Journal Article
Peacock, T. P., Benton, D. J., James, J., Sadeyen, J. R., Chang, P. X., Sealy, J. E., Bryant, J. E., Martin, S. R., Shelton, H., Barclay, W. S., & Iqbal, M. (2017). Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics. Journal of Virology, 91(14), UNSP e00218. https://doi.org/10.1128/JVI.00218-17

H9N2 avian influenza viruses are enzootic in poultry across Asia and North Africa, where they pose a threat to human health as both zoonotic agents and potential pandemic candidates. Poultry vaccination against H9N2 viruses has been employed in many... Read More about Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics.

Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis (2017)
Journal Article
Buzdugan, S. N., Vergne, T., Grosbois, V., Delahay, R. J., & Drewe, J. A. (2017). Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis. https://doi.org/10.1038/s41598-017-00806-4

Effective control of many diseases requires the accurate detection of infected individuals. Confidently ascertaining whether an individual is infected can be challenging when diagnostic tests are imperfect and when some individuals go for long period... Read More about Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis.

Malaria over-diagnosis in Cameroon: diagnostic accuracy of Fluorescence and Staining Technologies (FAST) Malaria Stain and LED microscopy versus Giemsa and bright field microscopy validated by polymerase chain reaction (2017)
Journal Article
Parsel, S. M., Gustafson, S. A., Friedlander, E., Shnyra, A. A., Adegbulu, A. J., Liu, Y., Parrish, N. M., Jamal, S. A., Lofthus, E., Ayuk, L., Awasom, C., Henry, C. J., & McArthur, C. P. (2017). Malaria over-diagnosis in Cameroon: diagnostic accuracy of Fluorescence and Staining Technologies (FAST) Malaria Stain and LED microscopy versus Giemsa and bright field microscopy validated by polymerase chain reaction. Infectious Diseases of Poverty, 6, 32. https://doi.org/10.1186/s40249-017-0251-0

Isolation and Potential for Transmission of Mycobacterium bovis at Human–livestock–wildlife Interface of the Serengeti Ecosystem, Northern Tanzania (2017)
Journal Article
Katale, B. Z., Mbugi, E. V., Siame, K. K., Keyyu, J. D., Kendall, S., Kazwala, R. R., Dockrell, H. M., Fyumagwa, R., Michel, A. L., Rweyemamu, M., Streicher, E. M., Warren, R. M., Van Helden, P., & Matee, M. I. (2017). Isolation and Potential for Transmission of Mycobacterium bovis at Human–livestock–wildlife Interface of the Serengeti Ecosystem, Northern Tanzania. Transboundary and Emerging Diseases, 64(3), 815-825. https://doi.org/10.1111/tbed.12445

Towards an integrated food safety surveillance system: a simulation study to explore the potential of combining genomic and epidemiological metadata (2017)
Journal Article
Hill, A. A., Crotta, M., Wall, B., Good, L., O'Brien, S. J., & Guitian, J. (2017). Towards an integrated food safety surveillance system: a simulation study to explore the potential of combining genomic and epidemiological metadata. Royal Society Open Science, 4, https://doi.org/10.1098/rsos.160721

Foodborne infection is a result of exposure to complex, dynamic food systems. The efficiency of foodborne infection is driven by ongoing shifts in genetic machinery. Next-generation sequencing technologies can provide high-fidelity data about the gen... Read More about Towards an integrated food safety surveillance system: a simulation study to explore the potential of combining genomic and epidemiological metadata.

The Lancet Countdown: tracking progress on health and climate change (2017)
Journal Article
Watts, N., Adger, W. N., Ayeb-Karlsson, S., Bzi, Y., Byass, P., Campbell-Lendrum, D., Colbourne, T., Cox, P., Davies, M., Depledge, M., Depoux, A., Dominguez-Salas, P., Drummond, P., Ekins, P., Flahaoult, A., Grace, D., Graham, H., Haines, A., Hamilton, I., Johnson, A., …Costello, A. (2017). The Lancet Countdown: tracking progress on health and climate change. https://doi.org/10.1016/S0140-6736%2816%2932124-9

Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era (2017)
Journal Article
Webster, J. P., Borlase, A. M., & Rudge, J. W. (2017). Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era. Philosophical Transactions of the Royal Society B: Biological Sciences, 372(1719), https://doi.org/10.1098/rstb.2016.0091

Multi-host infectious agents challenge our abilities to understand, predict and manage disease dynamics. Within this, many infectious agents are also able to use, simultaneously or sequentially, multiple modes of transmission. Furthermore, the relati... Read More about Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era.

Surveillance strategies for Classical Swine Fever in wild boar – a comprehensive evaluation study to ensure powerful surveillance (2017)
Journal Article
Schulz, K., Peyre, M., Staubach, C., Schauer, B., Schulz, J., Calba, C., Haesler, B., & Conraths, F. J. (2017). Surveillance strategies for Classical Swine Fever in wild boar – a comprehensive evaluation study to ensure powerful surveillance. https://doi.org/10.1038/srep43871

Surveillance of Classical Swine Fever (CSF) should not only focus on livestock, but must also include wild boar. To prevent disease transmission into commercial pig herds, it is therefore vital to have knowledge about the disease status in wild boar.... Read More about Surveillance strategies for Classical Swine Fever in wild boar – a comprehensive evaluation study to ensure powerful surveillance.

Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae (2017)
Journal Article
Bossé, J. T., Li, Y., Rogers, J., Fernandez Crespo, R., Li, Y., Chaudhuri, R. R., Holden, M. T. G., Maskell, D. J., Tucker, A. W., Wren, B. W., Rycroft, A. N., & Langford, P. R. (2017). Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae. Frontiers in Microbiology, 8(311), https://doi.org/10.3389/fmicb.2017.00311

The aim of this study was to evaluate the correlation between antimicrobial resistance (AMR) profiles of 96 clinical isolates of Actinobacillus pleuropneumoniae, an important porcine respiratory pathogen, and the identification of AMR genes in whole... Read More about Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae.