Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury (2017)
Journal Article
Carwardine, D., Prager, J., Neeves, J., Muir, E. M., Uney, J., Granger, N., & Wong, L. F. (2017). Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury. PLoS ONE, 12(12), https://doi.org/10.1371/journal.pone.0188967

Olfactory ensheathing cell (OEC) transplantation is a promising strategy for treating spinal cord injury (SCI), as has been demonstrated in experimental SCI models and naturally occurring SCI in dogs. However, the presence of chondroitin sulphate pro... Read More about Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury.

Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease (2017)
Journal Article
Stathopoulou, T., Kouki, M., Pypendop, B. H., Johnston, A., Papadimitriou, S., & Pelligand, L. (2017). Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease. Journal of Feline Medicine and Surgery, 20(8), 704-710. https://doi.org/10.1177/1098612X17727234

Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas (2017)
Journal Article
Benchekroun, G., Desquilbet, L., Herrtage, M. E., Jeffery, N. D., Rosenberg, D., & Granger, N. (2017). Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas. The Veterinary Journal, 227, 42-45. https://doi.org/10.1016/j.tvjl.2017.08.007

Pituitary macroadenomas compress the hypothalamus, which partly regulates heart rate and body temperature. The aim of this study was to investigate whether heart rate and/or body temperature could aid in clinically differentiating dogs with macroaden... Read More about Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas.

The genomic architecture of mastitis resistance in dairy sheep (2017)
Journal Article
Banos, G., Bramis, G., Bush, S. J., Clark, E. L., McCulloch, M. E. B., Smith, J., …Psifidi, A. (2017). The genomic architecture of mastitis resistance in dairy sheep. BMC Genomics, 18, 624. https://doi.org/10.1186/s12864-017-3982-1

Mastitis is the most prevalent disease in dairy sheep with major economic, hygienic and welfare implications. The disease persists in all dairy sheep production systems despite the implementation of improved management practises. Selective breeding f... Read More about The genomic architecture of mastitis resistance in dairy sheep.

Comparison of veterinary drugs and veterinary homeopathy: part 1 (2017)
Journal Article
Lees, P., Chambers, D., Pelligand, L., Toutain, P. L., Whiting, M., & Whitehead, M. L. (2017). Comparison of veterinary drugs and veterinary homeopathy: part 1. Veterinary Record, 181(7), 170-176. https://doi.org/10.1136/vr.104278

For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of v... Read More about Comparison of veterinary drugs and veterinary homeopathy: part 1.

Cohort Profile: The 'Bristol Cats Study' (BCS)-a birth cohort of kittens owned by UK households (2017)
Journal Article
Murray, J. K., Casey, R. A., Gale, E., Buffington, C. A. T., Roberts, C., Kinsman, R. H., & Gruffydd-Jones, T. J. (2017). Cohort Profile: The 'Bristol Cats Study' (BCS)-a birth cohort of kittens owned by UK households. International Journal of Epidemiology, 46(6), 1749+. https://doi.org/10.1093/ije/dyx066

Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats (2017)
Journal Article
Doodnaught, G. M., Monteiro, B. P., Benito, J., Edge, D., Beaudry, F., Pelligand, L., & Steagall, P. (2017). Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats. PLoS ONE, 12(4), w0176443. https://doi.org/10.1371/journal.pone.0176443

The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in cats.

Serum biomarkers of oxidative stress in dogs with idiopathic inflammatory bowel disease (2017)
Journal Article
Rubio, C. P., Martínez-Subiela, S., Hernández-Ruiz, J., Tvarijonaviciute, A., Cerón, J. J., & Allenspach, K. (2017). Serum biomarkers of oxidative stress in dogs with idiopathic inflammatory bowel disease. https://doi.org/10.1016/j.tvjl.2017.02.003

Owner perception of focal seizures in canine epilepsy (2017)
Journal Article
Packer, R. M. A., Lucas, R., & Volk, H. A. (2017). Owner perception of focal seizures in canine epilepsy. Veterinary Record, 180(6), 150. https://doi.org/10.1136/vr.104099

The pharmacological regulation of cellular mitophagy (2017)
Journal Article
Georgakopoulos, N. D., Wells, G., & Campanella, M. (2017). The pharmacological regulation of cellular mitophagy. Nature Chemical Biology, 13, 136-146. https://doi.org/10.1038/nchembio.2287

What is the true in vitro potency of oxytetracycline for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida? (2017)
Journal Article
Dorey, L., Hobson, S., & Lees, P. (2017). What is the true in vitro potency of oxytetracycline for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida?. Journal of Veterinary Pharmacology and Therapeutics, 40(5), 517-529. https://doi.org/10.1111/jvp.12386

The pharmacodynamics of oxytetracycline was determined for pig respiratory tract pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida. Indices of potency were determined for the following: (i) two matrices, broth and pig serum; (ii) f... Read More about What is the true in vitro potency of oxytetracycline for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida?.