Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas

Benchekroun, G; Desquilbet, L; Herrtage, M E; Jeffery, N D; Rosenberg, D; Granger, N

Abstract

Pituitary macroadenomas compress the hypothalamus, which partly regulates heart rate and body temperature. The aim of this study was to investigate whether heart rate and/or body temperature could aid in clinically differentiating dogs with macroadenomas from dogs with microadenomas (i.e. small non-compressive pituitary mass). Two groups of dogs diagnosed with pituitary-dependent hyperadrenocorticism (i.e. Cushing’s disease) were included. Heart rate and body temperature were collected on initial presentation before any procedure. Dogs with macroadenoma had a significantly lower heart rate and body temperature (P < 0.01) compared to dogs with microadenoma. We suggest that the combined cut-off values of 84 beats per minutes and 38.3 °C in dogs with Cushing’s disease, especially with vague neurological signs (nine of 12 dogs = 75%), might help to suspect the presence of a macroadenoma.

Citation

Benchekroun, G., Desquilbet, L., Herrtage, M. E., Jeffery, N. D., Rosenberg, D., & Granger, N. (2017). Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas. The Veterinary Journal, 227, 42-45. https://doi.org/10.1016/j.tvjl.2017.08.007

• Journal Article Type: Other
• Acceptance Date: Aug 23, 2017
• Publication Date: Sep 6, 2017
• Deposit Date: Sep 1, 2017
• Publicly Available Date: Sep 1, 2018
• Journal: VETERINARY JOURNAL
• Print ISSN: 1090-0233
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 227
• Pages: 42-45
• DOI: https://doi.org/10.1016/j.tvjl.2017.08.007
• Public URL: https://rvc-repository.worktribe.com/output/1390620