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A study of tuberculosis in road traffic-killed badgers on the edge of the British bovine TB epidemic area (2018)
Journal Article
Sandoval Barron, E., Swift, B. M. C., Chantrey, J., Christley, R., Gardner, R., Jewell, C., …Bennett, M. (2018). A study of tuberculosis in road traffic-killed badgers on the edge of the British bovine TB epidemic area. https://doi.org/10.1038/s41598-018-35652-5

The role of badgers in the geographic expansion of the bovine tuberculosis (bTB) epidemic in England is unknown: indeed there have been few published studies of bTB in badgers outside of the Southwest of England where the infection is now endemic in... Read More about A study of tuberculosis in road traffic-killed badgers on the edge of the British bovine TB epidemic area.

Comparison of 2016–17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe (2018)
Journal Article
Alarcon, P., Brouwer, A., Vekatesh, D., Duncan, D., Dovas, C. I., Georgiades, G., …Brown, I. H. (2018). Comparison of 2016–17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe. https://doi.org/10.3201/eid2412.171860

We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016–17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016–17 epizootic was the... Read More about Comparison of 2016–17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe.

Dissecting the Genomic Architecture of Resistance to Eimeria maxima Parasitism in the Chicken (2018)
Journal Article
Boulton, K., Nolan, M. J., Wu, Z., Riggio, V., Matika, O., Harman, K., …Psifidi, A. (2018). Dissecting the Genomic Architecture of Resistance to Eimeria maxima Parasitism in the Chicken. Frontiers in Genetics, 9, https://doi.org/10.3389/fgene.2018.00528

Coccidiosis in poultry, caused by protozoan parasites of the genus Eimeria, is an intestinal disease with substantial economic impact. With the use of anticoccidial drugs under public and political pressure, and the comparatively higher cost of live-... Read More about Dissecting the Genomic Architecture of Resistance to Eimeria maxima Parasitism in the Chicken.

Decreased nematode clearance & anti-phosphorylcholine specific IgM responses in mannose-binding lectin deficient mice (2018)
Journal Article
Ahmed, R., Cadman, E. T., Snapper, C. M., & Lawrence, R. A. (2018). Decreased nematode clearance & anti-phosphorylcholine specific IgM responses in mannose-binding lectin deficient mice. https://doi.org/10.1111/imcb.12219

Brugia malayi is a nematode that causes human lymphatic filariasis. Previously, we showed that mannose binding lectin (MBL) ‐A is necessary for clearance of B. malayi microfilariae in mice and presence of MBL‐A is linked with maximal levels of parasi... Read More about Decreased nematode clearance & anti-phosphorylcholine specific IgM responses in mannose-binding lectin deficient mice.

Draft genome assembly of the poultry red mite, Dermanyssus gallinae (2018)
Journal Article
Burgess, S. T. G., Bartley, K., Nunn, F., Wright, H. W., Hughes, M., Gemmell, M., …Nisbet, A. J. (2018). Draft genome assembly of the poultry red mite, Dermanyssus gallinae. Microbiology Resource Announcements, 7(18), https://doi.org/10.1128/MRA.01221-18

The poultry red mite, Dermanyssus gallinae, is a major worldwide concern in the egg-laying industry. Here, we report the first draft genome assembly and gene prediction of Dermanyssus gallinae, based on combined PacBio and MinION long-read de novo se... Read More about Draft genome assembly of the poultry red mite, Dermanyssus gallinae.

Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators (2018)
Journal Article
Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, H. M., Franzyk, H., & Guardabassi, L. (2018). Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators. International Journal of Antimicrobial Agents, 53(6), 868-872. https://doi.org/10.1016/j.ijantimicag.2018.10.025

Gram-negative bacterial pathogens are intrinsically resistant to several antibiotics that are not able to penetrate the cell envelope barrier. The aim of this study was to identify peptides that at low concentrations induce susceptibility to these an... Read More about Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators.

Genetic diversity and population structure of Angiostrongylus vasorum parasites within and between local urban foxes (Vulpes Vulpes) (2018)
Journal Article
Blanch-Lazaro, B., Mitton, Z., Tudor, C., Hindle, J., Martineau, H., Fox, M. T., & Blake, D. P. (2018). Genetic diversity and population structure of Angiostrongylus vasorum parasites within and between local urban foxes (Vulpes Vulpes). Veterinary Parasitology, 262, 42-46. https://doi.org/10.1016/j.vetpar.2018.09.008

Angiostrongylus vasorum is a nematode parasite of the pulmonary arteries and heart that infects domestic and wild canids. Dogs (Canis familiaris) and red foxes (Vulpes vulpes) are the most commonly affected definitive hosts. Recent studies suggest th... Read More about Genetic diversity and population structure of Angiostrongylus vasorum parasites within and between local urban foxes (Vulpes Vulpes).

Exploring the fate of cattle herds with inconclusive reactors to the tuberculin skin test (2018)
Journal Article
Brunton, L. A., Prosser, A., Downs, S. H., & Pfeiffer, D. U. (2018). Exploring the fate of cattle herds with inconclusive reactors to the tuberculin skin test. Frontiers in Veterinary Science, 5(228), https://doi.org/10.3389/fvets.2018.00228

Bovine tuberculosis (TB) is an important animal health issue in many parts of the world. In England and Wales, the primary test to detect infected animals is the single intradermal comparative cervical tuberculin test, which compares immunological re... Read More about Exploring the fate of cattle herds with inconclusive reactors to the tuberculin skin test.

Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5 (2018)
Journal Article
Tombacz, K., Burgess, G., Holder, A. L., Werners, A., & Werling, D. (2018). Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5. Innate Immunity, https://doi.org/10.1177/1753425918798450

Toxoplasma gondii is responsible for one of the most prevalent infections in people. T. gondii profilin (TgPr) is a protein integral to parasite movement and cellular invasion. Murine TLR has been described to bind TgPr. Furthermore, more recently, h... Read More about Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5.

Mapping Nairobi's dairy food system: An essential analysis for policy, industry and research (2018)
Journal Article
Kiambi, S., Alarcon, P., Rushton, J., Murungi, M. K., Muinde, P., Akoko, J., …Fèvre, E. M. (2018). Mapping Nairobi's dairy food system: An essential analysis for policy, industry and research. Agricultural Systems, 167, 47-60. https://doi.org/10.1016/j.agsy.2018.08.007

Demand for dairy products in sub-Saharan Africa, is expected to triple by 2050, while limited increase in supply is predicted. This poses significant food security risk to low income households. Understanding how the dairy food system operates is ess... Read More about Mapping Nairobi's dairy food system: An essential analysis for policy, industry and research.

The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease (2018)
Journal Article
Souza, C. K., Rajão, D. S., Sandbulte, M. R., Lopes, S., Lewis, N. S., Loving, C. L., …Vincent, A. L. (2018). The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease. Vaccine, 36(41), 6103-6110. https://doi.org/10.1016/j.vaccine.2018.08.072

Influenza A virus (IAV) causes a disease burden in the swine industry in the US and is a challenge to prevent due to substantial genetic and antigenic diversity of IAV that circulate in pig populations. Whole inactivated virus (WIV) vaccines formulat... Read More about The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease.

A culture-independent method for studying transfer of IncI1 plasmids from wild-type Escherichia coli in complex microbial communities (2018)
Journal Article
Anjum, M., Madsen, J. S., Espinosa-Gongora, C., Jana, B., Wiese, M., Nielsen, D. S., …Guardabassi, L. (2018). A culture-independent method for studying transfer of IncI1 plasmids from wild-type Escherichia coli in complex microbial communities. Journal of Microbiological Methods, 152, 18-26. https://doi.org/10.1016/j.mimet.2018.07.009

IncI1 plasmids play a central role in the transfer of antimicrobial resistance genes among Enterobacteriaceae in animals and humans. Knowledge on the dynamics of IncI1 plasmid transfer is limited, mainly due to lack of culture-independent methods tha... Read More about A culture-independent method for studying transfer of IncI1 plasmids from wild-type Escherichia coli in complex microbial communities.

Cutaneous Botryomycosis in Two Pet Rabbits (2018)
Journal Article
Hedley, J., Stapleton, N., Muir, C., Priestnall, S. L., & Smith, K. (2018). Cutaneous Botryomycosis in Two Pet Rabbits. Journal of Exotic Pet Medicine, 28, 143-147. https://doi.org/10.1053/j.jepm.2018.01.005

A 5-year-old male neutered rabbit was presented for assessment of multiple abscesses, which had appeared suddenly over the ventrum, perineum and hindlimbs over the previous few days. Thirteen abscesses were surgically excised. Culture revealed Pseudo... Read More about Cutaneous Botryomycosis in Two Pet Rabbits.

Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae) (2018)
Journal Article
Catalano, S., Bâ, K., Diouf, N., Léger, E., Verocai, G., & Webster, J. P. (2018). Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae). Parasitology, 146(3), 299-304. https://doi.org/10.1017/S0031182018001427

Hydatigera (Cestoda: Taeniidae) is a recently resurrected genus including species seldom investigated in sub-Saharan Africa. We surveyed wild small mammal populations in the areas of Richard Toll and Lake Guiers, Senegal, with the objective to evalua... Read More about Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae).

Spatio-temporal and risk factor analysis of alleles related to Scrapie resistance in sheep in Great Britain before, during and after a national breeding program (2018)
Journal Article
Alarcon, P., Marco-Jimenez, F., Arnold, M., Wolf, A., Rajanayagam, B., Stevens, K., & Adkin, A. (2018). Spatio-temporal and risk factor analysis of alleles related to Scrapie resistance in sheep in Great Britain before, during and after a national breeding program. Preventive Veterinary Medicine, 159, 12-21. https://doi.org/10.1016/j.prevetmed.2018.08.008

Certain genotypes of sheep have been identified to increase their susceptibility (the VRQ allele) or resistance (the ARR allele) to classical scrapie. This study’s aim was to assess the spatio-temporal pattern of the ARR and VRQ alleles in GB and to... Read More about Spatio-temporal and risk factor analysis of alleles related to Scrapie resistance in sheep in Great Britain before, during and after a national breeding program.

Anthropogenic environmental drivers of antimicrobial resistance in wildlife (2018)
Journal Article
Swift, B. M. C., Bennett, M., Waller, K., Dodd, C., Murray, A., Gomes, R. L., …Arnold, K. E. (2018). Anthropogenic environmental drivers of antimicrobial resistance in wildlife. Science of the Total Environment, 649, 12-20. https://doi.org/10.1016/j.scitotenv.2018.08.180

The isolation of antimicrobial resistant bacteria (ARB) from wildlife living adjacent to humans has led to the suggestion that such antimicrobial resistance (AMR) is anthropogenically driven by exposure to antimicrobials and ARB. However, ARB have al... Read More about Anthropogenic environmental drivers of antimicrobial resistance in wildlife.

Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions (2018)
Journal Article
Hoelzer, K., Bielke, L., Blake, D. P., Cox, E., Cutting, S. M., Devriendt, B., …Van Immerseel, F. (2018). Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions. BMC Veterinary Research, 49(70), https://doi.org/10.1186/s13567-018-0561-7

Vaccines and other alternative products are central to the future success of animal agriculture because they can help minimize the need for antibiotics by preventing and controlling infectious diseases in animal populations. To assess scientific adva... Read More about Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions.