Use of proteins identified through a functional genomic screen to develop a protein subunit vaccine that provides significant protection against virulent Streptococcus suis in pigs (2018)
Journal Article
Brockmeier, S. L., Loving, C. L., Nicholson, T. L., Wang, J., Peters, S. E., Weinert, L., …Tucker, A. W. (2018). Use of proteins identified through a functional genomic screen to develop a protein subunit vaccine that provides significant protection against virulent Streptococcus suis in pigs. Infection and Immunity, 86(3), e00559. https://doi.org/10.1128/IAI.00559-17

Streptococcus suis is a bacterium that is commonly carried in the respiratory tract and that is also one of the most important invasive pathogens of swine, commonly causing meningitis, arthritis, and septicemia. Due to the existence of many serotypes... Read More about Use of proteins identified through a functional genomic screen to develop a protein subunit vaccine that provides significant protection against virulent Streptococcus suis in pigs.

Phenotypic indications of FtsZ inhibition in hok/sok-induced bacterial growth changes and stress response (2018)
Journal Article
Chukwudi, C. U., & Good, L. (2018). Phenotypic indications of FtsZ inhibition in hok/sok-induced bacterial growth changes and stress response. Microbial Pathogenesis, 114, 393-401. https://doi.org/10.1016/j.micpath.2017.12.023

The hok/sok locus has been shown to enhance the growth of bacteria in adverse growth conditions such as high temperature, low starting-culture densities and antibiotic treatment. This is in addition to their well-established plasmid-stabilization eff... Read More about Phenotypic indications of FtsZ inhibition in hok/sok-induced bacterial growth changes and stress response.

A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle (2018)
Journal Article
Meyer, A., Bond, K., Van Winden, S. C. L., Green, M., & Guitian, J. (2018). A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle. Preventive Veterinary Medicine, 150, 30-37. https://doi.org/10.1016/j.prevetmed.2017.11.016

Johne’s disease is a serious wasting disease of ruminants that is of high economic importance for the dairy sector in particular. The chronic nature of the disease, the fluctuations in antibody levels and the limited ability of diagnostic tests to id... Read More about A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle.

Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya (2018)
Journal Article
Onono, J. O., Alarcon, P., Karani, M., Muinde, P., Akoko, J. M., Maud, C., …Rushton, J. (2018). Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya. Agricultural Systems, 159, 1-8. https://doi.org/10.1016/j.agsy.2017.10.001

Commercial layer and indigenous chicken farming in Nairobi and associated activities in the egg value chains are a source of livelihood for urban families. A value chain mapping framework was used to describe types of inputs and outputs from chicken... Read More about Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya.

Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells (2018)
Journal Article
Williams, R. S. B., & Bate, C. (2018). Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells. Neuropharmacology, 128, 54-62. https://doi.org/10.1016/j.neuropharm.2017.09.031

The amyloid hypothesis of Alzheimer's disease suggests that synaptic degeneration and pathology is caused by the accumulation of amyloid-β (Aβ) peptides derived from the amyloid precursor protein (APP). Subsequently, soluble Aβ oligomers cause the lo... Read More about Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells.

Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard (2017)
Journal Article
Clements, M. N., Donnelly, C. A., Fenwick, A., Kabatereine, N. B., Knowles, S. C. L., Meité, A., …Fleming, F. M. (2017). Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard. PLoS Neglected Tropical Diseases, https://doi.org/10.1371/journal.pntd.0006102

Zoonotic potential of Salmonella enterica carried by pet tortoises (2017)
Journal Article
Bruce, H. L., Barrow, P. A., & Rycroft, A. N. (2017). Zoonotic potential of Salmonella enterica carried by pet tortoises. Veterinary Record, 182(5), 141. https://doi.org/10.1136/vr.104457

The prevalence of Salmonella in chelonians is not known in the UK and it is not clear whether such Salmonella strains would be pathogenic for human beings. Some strains, such as members of the Arizonae subgroup, may be unable to cause anything more t... Read More about Zoonotic potential of Salmonella enterica carried by pet tortoises.

Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß (2017)
Journal Article
Bate, C. (2017). Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß. Journal of Experimental Neuroscience, 11, https://doi.org/10.1177/1179069517733096

Soluble amyloid-β (Aβ) oligomers, a key driver of pathogenesis in Alzheimer disease, bind to cellular prion proteins (PrPC) expressed on synaptosomes resulting in increased cholesterol concentrations, movement of cytoplasmic phospholipase A2 (cPLA2)... Read More about Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß.

Linking disease epidemiology and livestock productivity: The case of bovine respiratory disease in France (2017)
Journal Article
Delabouglise, A., James, A., Valarcher, J. F., Haggluend, S., Raboisson, D., & Rushton, J. (2017). Linking disease epidemiology and livestock productivity: The case of bovine respiratory disease in France. PLoS ONE, 12, e0189090. https://doi.org/10.1371/journal.pone.0189090

Concerns are growing over the impact of livestock farming on environment and public health. The livestock industry is faced with the double constraint of limiting its use of natural resources and antimicrobials while ensuring its economic sustainabil... Read More about Linking disease epidemiology and livestock productivity: The case of bovine respiratory disease in France.

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme (2017)
Journal Article
Gower, C. M., Gehre, F., Marques, S. R., Lamberton, P. H. L., Lwambo, N. J., & Webster, J. P. (2017). Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme. https://doi.org/10.1186/s13071-017-2533-6

We conducted combined in vitro PZQ efficacy testing with population genetic analyses of S. mansoni collected from children from two schools in 2010, five years after the introduction of a National Control Programme. Children at one school had receive... Read More about Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme.

Efficacy of a Topical Formulation Containing Emodepside and Praziquantel (Profender®, Bayer) against Nematodes in Captive Tortoises (2017)
Journal Article
Tang, P. K., Pellett, S., Blake, D. P., & Hedley, J. (2017). Efficacy of a Topical Formulation Containing Emodepside and Praziquantel (Profender®, Bayer) against Nematodes in Captive Tortoises. https://doi.org/10.5818/17-04-107.1

Gastrointestinal parasites are commonly diagnosed in captive tortoises. In response, fenbendazole has traditionally been used as an anthelmintic, either in single or repeated doses. However, fenbendazole requires oral administration and the process c... Read More about Efficacy of a Topical Formulation Containing Emodepside and Praziquantel (Profender®, Bayer) against Nematodes in Captive Tortoises.

Economics of One Health: Costs and benefits of integrated West Nile virus surveillance in Emilia-Romagna (2017)
Journal Article
Paternoster, G., Babo Martins, S., Mattivi, A., Cagarelli, R., Angelini, P., Bellini, R., …Tamba, M. (2017). Economics of One Health: Costs and benefits of integrated West Nile virus surveillance in Emilia-Romagna. PLoS ONE, 12(11), e0188156. https://doi.org/10.1371/journal.pone.0188156

Since 2013 in Emilia-Romagna, Italy, surveillance information generated in the public health and in the animal health sectors has been shared and used to guide public health interventions to mitigate the risk of West Nile virus (WNV) transmission via... Read More about Economics of One Health: Costs and benefits of integrated West Nile virus surveillance in Emilia-Romagna.

Knowledge gaps in host-parasite interaction preclude accurate assessment of meat-borne exposure to Toxoplasma gondii (2017)
Journal Article
Crotta, M., Limon, G., Blake, D. P., & Guitian, J. (2017). Knowledge gaps in host-parasite interaction preclude accurate assessment of meat-borne exposure to Toxoplasma gondii. International Journal of Food Microbiology, https://doi.org/10.1016/j.ijfoodmicro.2016.12.010

14-3-3s Protein Expression in Canine Renal Cell Carcinomas (2017)
Journal Article
Suárez-Bonnet, A., Lara-García, A., Stoll, A. L., Carvalho, S., & Priestnall, S. L. (2017). 14-3-3s Protein Expression in Canine Renal Cell Carcinomas. Veterinary Pathology, 55(2), 233-240. https://doi.org/10.1177/0300985817738097

14-3-3σ is a protein expressed in many epithelial tissues associated with essential cell functions, including cell-cycle control, apoptosis, and cytoskeletal integrity. There is a paucity of knowledge of the tumorigenesis of canine renal cell carcino... Read More about 14-3-3s Protein Expression in Canine Renal Cell Carcinomas.

A Qualitative Stakeholder Analysis of Avian Influenza Policy in Bangladesh (2017)
Journal Article
Chattopadhyay, K., Fournié, G., Abul Kalam, M., Biswas, P. K., Hoque, A., & Debnath, N. C. (2017). A Qualitative Stakeholder Analysis of Avian Influenza Policy in Bangladesh. EcoHealth, https://doi.org/10.1007/s10393-017-1285-2

Avian influenza is a major animal and public health concern in Bangladesh. A decade after development and implementation of the first national avian influenza and human pandemic influenza preparedness and response plan in Bangladesh, a two-stage qual... Read More about A Qualitative Stakeholder Analysis of Avian Influenza Policy in Bangladesh.

A newly described strain of Eimeria arloingi (strain A) belongs to the phylogenetic group of ruminant-infecting pathogenic species, which replicate in host endothelial cells in vivo (2017)
Journal Article
Silva, L. M. R., Chávez-Maya, F., Macdonald, S., Pegg, E., Blake, D. P., Taubert, A., & Hermosilla, C. (2017). A newly described strain of Eimeria arloingi (strain A) belongs to the phylogenetic group of ruminant-infecting pathogenic species, which replicate in host endothelial cells in vivo. Veterinary Parasitology, 248, 28-32. https://doi.org/10.1016/j.vetpar.2017.10.014

Coccidiosis caused by Eimeria species is an important disease worldwide, particularly in ruminants and poultry. Eimeria infection can result in significant economic losses due to costs associated with treatment and slower growth rates, or even with m... Read More about A newly described strain of Eimeria arloingi (strain A) belongs to the phylogenetic group of ruminant-infecting pathogenic species, which replicate in host endothelial cells in vivo.

Herd-level prevalence of selected endemic infectious diseases of dairy cows in Great Britain (2017)
Journal Article
Velasova, M., Damaso, A., Chengat Prakashbabu, B., Gibbons, J., Wheelhouse, N., Longbottom, D., …Guitian, J. (2017). Herd-level prevalence of selected endemic infectious diseases of dairy cows in Great Britain. Journal of Dairy Science, 100(11), 9215-9233. https://doi.org/10.3168/jds.2016-11863

To implement appropriate and effective disease control programs at the national level, up-to-date and unbiased information on disease frequency is needed. The aim of this study was to estimate the prevalence of selected endemic infectious diseases in... Read More about Herd-level prevalence of selected endemic infectious diseases of dairy cows in Great Britain.

Recombinant anticoccidial vaccines - a cup half full? (2017)
Journal Article
Blake, D. P., Pastor-Fernández, I., Nolan, M. J., & Tomley, F. M. (2017). Recombinant anticoccidial vaccines - a cup half full?. Infection, Genetics and Evolution, 55, 358-365. https://doi.org/10.1016/j.meegid.2017.10.009

Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The occurrence of coccidiosis is currently controlled through a combination of good husbandry, chemoprophylaxis and/or live parasite vaccination; however, scalable... Read More about Recombinant anticoccidial vaccines - a cup half full?.

Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing (2017)
Journal Article
Halder, J. B., Benton, J., Julé, A. M., Guérin, P. J., Olliaro, P. L., Basáñez, M., & Walker, M. (2017). Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing. PLoS Neglected Tropical Diseases, 11(10), e0006053. https://doi.org/10.1371/journal.pntd.0006053

Preventive chemotherapy and transmission control (PCT) by mass drug administration is the cornerstone of the World Health Organization (WHO)’s policy to control soil-transmitted helminthiases (STHs) caused by Ascaris lumbricoides (roundworm), Trichur... Read More about Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing.

Using mixed methods to assess food security and coping strategies: a case study among smallholders in the Andean region (2017)
Journal Article
Limon, G., Fournié, G., Lewis, E. G., Dominguez-Salas, P., Leyton-Michovich, D., Gonzales-Gustavson, E. A., …Guitian, J. (2017). Using mixed methods to assess food security and coping strategies: a case study among smallholders in the Andean region. Food Security, 9(5), 1019-1040. https://doi.org/10.1007/s12571-017-0713-z

International organizations and national governments in resource-scarce settings regularly support programs for the control of animal diseases with the aim of improving smallholder food security. However, the impact of such disease control programs o... Read More about Using mixed methods to assess food security and coping strategies: a case study among smallholders in the Andean region.