Outputs (23)

Runx proteins regulate Foxp3 expression
Journal Article
Bruno, L., Mazzarella, L., Hoogenkamp, M., Hertweck, A., Cobb, B. S., Sauer, S., Hadjur, S., Leleu, M., Naoe, Y., Telfer, J. C., Bonifer, C., Taniuchi, L., Fisher, A. G., & Merkenschlager, M. (in press). Runx proteins regulate Foxp3 expression. Journal of Experimental Medicine, 206(11), 2329-37. https://doi.org/10.1084/jem.20090226

Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds
Journal Article
Zhao, J., Lee, M. C., Momin, A., Cendan, C. M., Shepherd, S. T., Baker, M. D., Asante, C., Bee, L., Bethry, A., Perkins, J. R., Nassar, M. A., Abrahamsen, B., Dickenson, A., Cobb, B. S., Merkenschlager, M., & Wood, J. N. Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds. Journal of Neuroscience, 30(32), 10860-10871. https://doi.org/10.1523/jneurosci.1980-10.2010

An Early Developmental Role for miRNAs in the Maintenance of Extraembryonic Stem Cells in the Mouse Embryo
Journal Article
Spruce, T., Pernaute, B., Di-Gregorio, A., Cobb, B. S., Merkenschlager, M., & Manzanares, M. An Early Developmental Role for miRNAs in the Maintenance of Extraembryonic Stem Cells in the Mouse Embryo. Developmental Cell, 19(2), 207-219. https://doi.org/10.1016/j.devcel.2010.07.014

MicroRNA miR-125a controls hematopoietic stem cell number
Journal Article
Guo, S., Lu, J., Schlanger, R., Zhang, H., Wang, J. Y., Fox, M. C., Purton, L., Fleming, H. H., Cobb, B. S., Merkenschlager, M., Golub, T. R., & Scadden, D. T. MicroRNA miR-125a controls hematopoietic stem cell number. https://doi.org/10.1073/pnas.0913574107

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B cell lineage specification and pre-B cell differentiation
Journal Article
Ferreirós-Vidal, I., Carroll, T., Taylor, B., Terry, A., Liang, Z., Bruno, L., Dharmalingam, G., Khadayate, S., Cobb, B. S., Smale, S. T., Spivakov, M., Srivastava, P., Petretto, E., Fisher, A. G., & Merkenschlager, M. Genome-wide identification of Ikaros targets elucidates its contribution to mouse B cell lineage specification and pre-B cell differentiation. Blood, 121(10), 1769-82. https://doi.org/10.1182/blood-2012-08-450114

DIFFERENTIAL EXPRESSION OF THE TRANSCRIPTS ENCODING EPIDERMAL GROWTH FACTOR RECEPTOR AND ITS LIGANDS BY CD4(+) T HELPER SUBSETS IN RESPONSE TO T CELL RECEPTOR ENGAGEMENT
Presentation / Conference Contribution
Carney, K., Chan, W. Y., Singh, Y., Cobb, B. S., De Mestre, A. M., Affleck, K., & Garden, O. A. DIFFERENTIAL EXPRESSION OF THE TRANSCRIPTS ENCODING EPIDERMAL GROWTH FACTOR RECEPTOR AND ITS LIGANDS BY CD4(+) T HELPER SUBSETS IN RESPONSE TO T CELL RECEPTOR ENGAGEMENT

VALIDATION OF TWO COMMERCIAL ANTIBODIES FOR THE DETECTION OF CANINE INTRACELLULAR IL-10
Presentation / Conference Contribution
Wu, J., Carney, K., Singh, Y., Cobb, B. S., & Garden, O. A. VALIDATION OF TWO COMMERCIAL ANTIBODIES FOR THE DETECTION OF CANINE INTRACELLULAR IL-10

DOWN-REGULATION OF MIR-22 AND MIR-26A INDEPENDENTLY INDUCES INSULIN RESISTANCE IN L6 MYOTUBES
Presentation / Conference Contribution
Andersen, D. K., Cobb, B. S., & Cleasby, M. E. DOWN-REGULATION OF MIR-22 AND MIR-26A INDEPENDENTLY INDUCES INSULIN RESISTANCE IN L6 MYOTUBES

MicroRNAs control the apoptotic threshold in primed Pluripotent stem cells through regulation of BIM
Journal Article
Pernaute, B., Spruce, T., Smith, K. M., Sanchez-Nieto, J. M., Manzanares, M., Cobb, B. S., & Rodriguez, T. A. (in press). MicroRNAs control the apoptotic threshold in primed Pluripotent stem cells through regulation of BIM. https://doi.org/10.1101/gad.245621.114

Mammalian primed pluripotent stem cells have been shown to be highly susceptible to cell death stimuli due to their low apoptotic threshold, but how this threshold is regulated remains largely unknown. Here we identify microRNA (miRNA)-mediated regul... Read More about MicroRNAs control the apoptotic threshold in primed Pluripotent stem cells through regulation of BIM.

A ROLE FOR MIR-22 AND MIR-26A IN MUSCLE GLUCOSE UPTAKE AND INSULIN SENSITIVITY
Presentation / Conference Contribution
Andersen, D. K., Cobb, B. S., & Cleasby, M. E. A ROLE FOR MIR-22 AND MIR-26A IN MUSCLE GLUCOSE UPTAKE AND INSULIN SENSITIVITY