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Loading-related Regulation of Transcription Factor EGR2/Krox-20 in Bone Cells Is ERK1/2 Protein-mediated and Prostaglandin, Wnt Signaling Pathway-, and Insulin-like Growth Factor-I Axis-dependent
Journal Article
Zaman, G., Sunters, A., Galea, G. L., Javaheri, B., Saxon, L. K., Moustafa, A., Armstrong, V. J., Price, J. S., & Lanyon, L. E. Loading-related Regulation of Transcription Factor EGR2/Krox-20 in Bone Cells Is ERK1/2 Protein-mediated and Prostaglandin, Wnt Signaling Pathway-, and Insulin-like Growth Factor-I Axis-dependent. Journal of Biological Chemistry, 287(6), 3946-3962. https://doi.org/10.1074/jbc.M111.252742

Loading-related regulation of the transcription factor EGR2/Krox-20 in bone cells is ERK 1/2 mediated and prostaglandin Wnt and IGF-I axis dependent
Journal Article
Zaman, G., Sunters, A., Galea, G. L., Javaheri, B., Saxon, L. K., Moustafa, A., Armstrong, V. J., Price, J. S., & Lanyon, L. E. Loading-related regulation of the transcription factor EGR2/Krox-20 in bone cells is ERK 1/2 mediated and prostaglandin Wnt and IGF-I axis dependent. Journal of Biological Chemistry, 287(6), 3946-3962. https://doi.org/10.1074/jbc.M111.252742

PPAR alpha-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status
Journal Article
Caton, P. W., Holness, M. J., Bishop-Bailey, D., & Sugden, M. C. (in press). PPAR alpha-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status. Biochemical Journal, 437(3), 521-530. https://doi.org/10.1042/BJ20110702

LXR (liver X receptor) and PPARα (peroxisome-proliferator-activated receptor α) are nuclear receptors that control the expression of genes involved in glucose and lipid homoeostasis. Using wild-type and PPARα-null mice fed on an LXR-agonist-supplemen... Read More about PPAR alpha-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.